Search Results - "Romas, Nicholas A."

Circulating tumor cells as Trojan Horse for understanding, preventing, and treating cancer: a critical appraisal by Mentis, Alexios-Fotios A., Grivas, Petros D., Dardiotis, Efthimios, Romas, Nicholas A., Papavassiliou, Athanasios G.

“…Circulating tumor cells (CTCs) are regarded as harbingers of metastases. Their ability to predict response to therapy, relapse, and resistance to treatment has…”
Get full text

PIWI family proteins as prognostic markers in cancer: a systematic review and meta-analysis by Mentis, Alexios-Fotios A., Dardiotis, Efthimios, Romas, Nicholas A., Papavassiliou, Athanasios G.

“…Background P-element-induced-wimpy-testis-(PIWI)-like proteins are implicated in germ cells’ regulation and detected in numerous cancer types. In this…”
Get full text

Interactions of sex hormone-binding globulin with target cells by Rosner, William, Hryb, Daniel J., Kahn, Scott M., Nakhla, Atif M., Romas, Nicholas A.

“…Sex hormone-binding globulin (SHBG) was initially described as a plasma protein synthesized in, and secreted by, the liver. It was discovered by its ability to…”
Get full text

Sex Hormone-binding Globulin in the Human Prostate Is Locally Synthesized and May Act as an Autocrine/Paracrine Effector by Hryb, Daniel J., Nakhla, Atif M., Kahn, Scott M., St. George, Jonathan, Levy, Nomi C., Romas, Nicholas A., Rosner, William

“…Sex hormone-binding globulin (SHBG) is a plasma protein synthesized and secreted by the liver. Its initial description stemmed from its ability to bind…”
Get full text

Phase I/II prospective trial of cancer-specific imaging using ultrasound spectrum analysis tissue-type imaging to guide dose-painting prostate brachytherapy by Ennis, Ronald D, Quinn, S. Aidan, Trichter, Frieda, Ryemon, Shannon, Jain, Anudh, Saigal, Kunal, Chandrashekhar, Sarayu, Romas, Nicholas A, Feleppa, Ernest J

“…Abstract Purpose To assess the technical feasibility, toxicity, dosimetry, and preliminary efficacy of dose-painting brachytherapy guided by ultrasound…”
Get full text

Sex hormone-binding globulin influences gene expression of LNCaP and MCF-7 cells in response to androgen and estrogen treatment by Kahn, Scott M, Li, Yu-Hua, Hryb, Daniel J, Nakhla, Atif M, Romas, Nicholas A, Cheong, Janice, Rosner, William

“…Sex hormone-binding globulin (SHBG), a plasma protein that binds androgens and estrogens, also participates in the initial steps of a membrane-based steroid…”
Get more information

Long-term 6-year experience with finasteride in patients with benign prostatic hyperplasia by Lowe, Franklin C, McConnell, John D, Hudson, Perry B, Romas, Nicholas A, Boake, Rex, Lieber, Michael, Elhilali, Mostafa, Geller, Jack, Imperto-McGinely, Juliane, Andriole, Gerald L, Bruskewitz, Reginald C, Walsh, Patrick C, Bartsch, Georg, Nacey, John N, Shah, Sukrut, Pappas, Frances, Ko, Amy, Cook, Thomas, Stoner, Elizabeth, Waldstreicher, Joanne

“…To summarize the 6-year clinical trial data with finasteride. Benign prostatic hyperplasia is a chronic and progressive disease and therefore assessment of…”
Get full text

Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane by Rosner, William, Hryb, Daniel J, Khan, M.Saeed, Nakhla, Atif M, Romas, Nicholas A

“…Sex hormone-binding globulin is a plasma glycoprotein that binds certain estrogens and androgens with high affinity. Over the past several years it has been…”
Get full text

Human sex hormone-binding globulin gene expression- multiple promoters and complex alternative splicing by Nakhla, Atif M, Hryb, Daniel J, Rosner, William, Romas, Nicholas A, Xiang, Zhaoying, Kahn, Scott M

“…Human sex hormone-binding globulin (SHBG) regulates free sex steroid concentrations in plasma and modulates rapid, membrane based steroid signaling. SHBG is…”
Get full text

Long-term treatment with finasteride in men with symptomatic benign prostatic hyperplasia: 10-year follow-up by Lam, John S, Romas, Nicholas A, Lowe, Franklin C

“…To evaluate the safety and efficacy of finasteride 5 mg during a 10-year period in men with enlarged prostates from a single center who participated in the…”
Get full text

Estradiol Activates the Prostate Androgen Receptor and Prostate-specific Antigen Secretion through the Intermediacy of Sex Hormone-binding Globulin by Nakhla, Atif M., Romas, Nicholas A., Rosner, William

“…These experiments were designed to examine the relationship between the effects of steroid hormones mediated by classic intracellular steroid hormone receptors…”
Get full text

Androgen and estrogen signaling at the cell membrane via G-proteins and cyclic adenosine monophosphate by Rosnera, William, Hryb, Daniel J., Khan, M.Saeed, Nakhla, Atif M., Romas, Nicholas A.

“…Androgens and estrogens are well-known to initiate their actions by binding to specific intracellular receptors. The steroid–receptor interaction, the…”
Get full text

Efficacy of finasteride is maintained in patients with benign prostatic hyperplasia treated for 5 years by Hudson, Perry B., Boake, Rex, Trachtenberg, John, Romas, Nicholas A., Rosenblatt, Sidney, Narayan, Perinchery, Geller, Jack, Lieber, Michael M., Elhilali, Mostafa, Norman, Richard, Patterson, Lynn, Perreault, Jean-Paul, Malek, Gholam H., Bruskewitz, Reginald C., Roy, Johnny B., Ko, Amy, Jacobsen, Carol A., Stoner, Elizabeth

“…Objectives. The purpose of this open-label study extension was to assess the long-term safety and efficacy of finasteride in the treatment of men with benign…”
Get full text

The control of the interaction of sex hormone-binding globulin with its receptor by steroid hormones by HRYB, D. J, SAEED KHAN, M, ROMAS, N. A, ROSNER, W

“…Sex hormone-binding globulins (SHBG) is a plasma glycoprotein that binds certain steroids. It, in turn, binds to a specific receptor on cell membranes. This…”
Get full text

Androgens, Estrogens, and Second Messengers by Rosner, William, Hryb, Daniel J., Khan, M.Saeed, Nakhla, Atif M., Romas, Nicholas A.

Get full text

Sex hormone-binding globulin: anatomy and physiology of a new regulatory system by Rosner, W, Hryb, D J, Khan, M S, Nakhla, A M, Romas, N A

“…Sex hormone-binding globulin (SHBG) is a plasma glycoprotein that binds a number of circulating steroid hormones (testosterone, dihydrotestosterone and…”
Get more information

Specific Binding of Human Corticosteroid-Binding Globulin to Cell Membranes by Hryb, Daniel J., Khan, M. Saeed, Romas, Nicholas A., Rosner, William

“…Specific binding sites for corticosteroid-binding globulin were detected on membranes prepared from human prostates. The binding sites are typical of membrane…”
Get full text

Delineation and synthesis of the membrane receptor-binding domain of sex hormone-binding globulin by Khan, M S, Hryb, D J, Hashim, G A, Romas, N A, Rosner, W

“…Sex hormone-binding globulin (SHBG) is a plasma glycoprotein which binds certain steroids. It, in turn, binds to a specific receptor on cell membranes. This…”
Get full text

Sex Hormone‐Binding Globulin Binding to Cell Membranes and Generation of a Second Messenger by ROSNER, WILLIAM, HRYB, DANIEL J., KHAN, M. SAEED, NAKHLA, ATIF M., ROMAS, NICHOLAS A.

Get full text

Epididymal metastasis from prostatic adenocarcinoma mimicking adenomatoid tumor by Rizk, C C, Scholes, J, Chen, S K, Ward, J, Romas, N A

“…A case of epididymal metastasis from prostatic carcinoma is presented. The initial histologic findings were suggestive of adenomatoid tumor, but a diagnosis of…”
Get more information