Search Results - "Romano, Rosaria"
-
1
Artificial Stone Associated Silicosis: A Systematic Review
Published in International journal of environmental research and public health (16-02-2019)“…Silicosis is a progressive fibrotic lung disease that is caused by the inhalation of respirable crystalline silica. Due to its high silica content, artificial…”
Get full text
Journal Article -
2
Structure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharide
Published in Proceedings of the National Academy of Sciences - PNAS (24-11-2020)“…Meningococcal meningitis remains a substantial cause of mortality and morbidity worldwide. Until recently, countries in the African meningitis belt were…”
Get full text
Journal Article -
3
The Impact of Shift-Work and Night Shift-Work on Thyroid: A Systematic Review
Published in International journal of environmental research and public health (27-02-2020)“…Thyroid hormones are regulated by the pituitary thyroid stimulating hormone (TSH), whose secretion presents a circadian rhythmicity. Indeed, it is conceivable…”
Get full text
Journal Article -
4
Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway
Published in Neurobiology of disease (01-01-2019)“…Chronic pain is associated with cognitive deficits. Palmitoylethanolamide (PEA) has been shown to ameliorate pain and pain-related cognitive impairments by…”
Get full text
Journal Article -
5
Glycoconjugate vaccines against antimicrobial resistant pathogens
Published in Expert review of vaccines (31-12-2023)“…INTRODUCTIONAntimicrobial resistance (AMR) is responsible for the death of millions worldwide and stands as a major threat to our healthcare systems, which are…”
Get full text
Journal Article -
6
Persistent increase of d -aspartate in d -aspartate oxidase mutant mice induces a precocious hippocampal age-dependent synaptic plasticity and spatial memory decay
Published in Neurobiology of aging (01-11-2011)“…Abstract The atypical amino acid d -aspartate ( d -Asp) occurs at considerable amounts in the developing brain of mammals. However, during postnatal life, d…”
Get full text
Journal Article -
7
Design of a novel vaccine nanotechnology-based delivery system comprising CpGODN-protein conjugate anchored to liposomes
Published in Journal of controlled release (10-07-2020)“…Although the well-known Toll like receptor 9 (TLR9) agonist CpGODN has shown promising results as vaccine adjuvant in preclinical and clinical studies, its in…”
Get full text
Journal Article -
8
Impact of Protein Nanoparticle Shape on the Immunogenicity of Antimicrobial Glycoconjugate Vaccines
Published in International journal of molecular sciences (01-04-2024)“…Protein self-assembling nanoparticles (NPs) can be used as carriers for antigen delivery to increase vaccine immunogenicity. NPs mimic the majority of invading…”
Get full text
Journal Article -
9
A stabilized glycomimetic conjugate vaccine inducing protective antibodies against Neisseria meningitidis serogroup A
Published in Nature communications (07-09-2020)“…Neisseria meningitidis serogroup A capsular polysaccharide (MenA CPS) consists of (1 → 6)-2-acetamido-2-deoxy-α-D-mannopyranosyl phosphate repeating units, O…”
Get full text
Journal Article -
10
Combined Chemical Synthesis and Tailored Enzymatic Elongation Provide Fully Synthetic and Conjugation-Ready Neisseria meningitidis Serogroup X Vaccine Antigens
Published in ACS chemical biology (20-04-2018)“…Studies on the polymerization mode of Neisseria meningitidis serogroup X capsular polymerase CsxA recently identified a truncated construct that can be…”
Get full text
Journal Article -
11
Streptococcus agalactiae Capsule Polymer Length and Attachment Is Determined by the Proteins CpsABCD
Published in The Journal of biological chemistry (10-04-2015)“…Background: The polysaccharide capsule is a major virulence factor of Streptococcus agalactiae. Results: Mutations of the genes cpsABCD result in aberrant…”
Get full text
Journal Article -
12
An eighteen-month follow-up study on the effects of Intravitreal Dexamethasone Implant in diabetic macular edema refractory to anti-VEGF therapy
Published in International journal of ophthalmology (18-10-2016)“…AIM: To evaluate the long-term efficacy and safety of dexamethasone implants in subjects affected by diabetic macular edema(DME) resistant to anti-vascular…”
Get full text
Journal Article -
13
Involvement of the peroxisome proliferator-activated receptor (PPAR) alpha in vascular response of endocannabinoids in the bovine ophthalmic artery
Published in European journal of pharmacology (15-05-2012)“…Endocannabinoids regulate vascular tone in a variety of vascular tissues. This study aimed to investigate the role of peroxisome proliferators-activated…”
Get full text
Journal Article -
14
Effects of bevacizumab on neuronal viability of retinal ganglion cells in rats
Published in Brain research (10-10-2012)“…Abstract The aim of this study was to investigate the effects of single and repeated intravitreal injections of bevacizumab on various retinal layers focusing…”
Get full text
Journal Article -
15
A2A adenosine receptor antagonism enhances synaptic and motor effects of cocaine via CB1 cannabinoid receptor activation
Published in PloS one (08-06-2012)“…Cocaine increases the level of endogenous dopamine (DA) in the striatum by blocking the DA transporter. Endogenous DA modulates glutamatergic inputs to…”
Get full text
Journal Article -
16
Development of a glycoconjugate vaccine to prevent meningitis in Africa caused by meningococcal serogroup X
Published in Proceedings of the National Academy of Sciences - PNAS (19-11-2013)“…Neisseria meningitidis is a major cause of bacterial meningitis worldwide, especially in the African meningitis belt, and has a high associated mortality. The…”
Get full text
Journal Article -
17
Hepatitis C virus (HCV) micro-elimination in the hospital setting: The results of the HCV Caserta hospital project
Published in Journal of infection and public health (01-05-2022)“…In the present study we evaluated the efficacy of an innovative model of HCV micro-elimination in a hospital setting in an area of high HCV prevalence. Between…”
Get full text
Journal Article -
18
Publisher Correction: A stabilized glycomimetic conjugate vaccine inducing protective antibodies against Neisseria meningitidis serogroup A
Published in Nature communications (25-11-2020)“…A Correction to this paper has been published: https://doi.org/10.1038/s41467-020-20120-4…”
Get full text
Journal Article -
19
A Multidisciplinary Structural Approach to the Identification of the Haemophilus influenzae Type b Capsular Polysaccharide Protective Epitope
Published in ACS central science (22-05-2024)“…Glycoconjugate vaccines so far licensed are generally composed of a native or size-reduced capsular polysaccharide conjugated to carrier proteins. Detailed…”
Get full text
Journal Article -
20
Transglutaminase inhibition: possible therapeutic mechanisms to protect cells from death in neurological disorders
Published in AIMS molecular science (01-01-2017)“…Transglutaminases are a family of Ca2+-dependent enzymes which catalyze post-translational modifications of proteins. The main activity of these enzymes is the…”
Get full text
Journal Article