Search Results - "Romano, E L"
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Local mapping of root orientation traits by X-ray micro-CT and 3d image analysis: A study case on carrot seedlings grown in simulated vs real weightlessness
Published in Plant methods (28-09-2024)“…Root phenotyping is particularly challenging because of complexity and inaccessibility of root apparatus. Orientation is one of the most important…”
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GATA3 induces mitochondrial biogenesis in primary human CD4+ T cells during DNA damage
Published in Nature communications (07-06-2021)“…GATA3 is as a lineage-specific transcription factor that drives the differentiation of CD4 + T helper 2 (Th2) cells, but is also involved in a variety of…”
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N-SREBP2 Provides a Mechanism for Dynamic Control of Cellular Cholesterol Homeostasis
Published in Cells (Basel, Switzerland) (01-08-2024)“…Cholesterol is required to maintain the functional integrity of cellular membrane systems and signalling pathways, but its supply must be closely and…”
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AlphaFold predicted structure of the Hsp90-like domains of the neurodegeneration linked protein sacsin reveals key residues for ATPase activity
Published in Frontiers in molecular biosciences (13-01-2023)“…The ataxia-linked protein sacsin has three regions of partial homology to Hsp90's N-terminal ATP binding domain. Although a crystal structure for this…”
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Dust grain size evolution in local galaxies: a comparison between observations and simulations
Published in Monthly notices of the Royal Astronomical Society (18-08-2022)“…ABSTRACT The evolution of the dust grain size distribution has been studied in recent years with great detail in cosmological hydrodynamical simulations taking…”
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Iron Overload Augments the Development of Atherosclerotic Lesions in Rabbits
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-1995)“…Iron, a major oxidant in vivo, could be involved in atherosclerosis through the induction of the formation of oxidized LDL, a major atherogenic factor. This…”
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Altered organization of the intermediate filament cytoskeleton and relocalization of proteostasis modulators in cells lacking the ataxia protein sacsin
Published in Human molecular genetics (15-08-2017)“…Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) is caused by mutations in the gene SACS, encoding the 520 kDa protein sacsin. Although…”
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A reduction in Drp1-mediated fission compromises mitochondrial health in autosomal recessive spastic ataxia of Charlevoix Saguenay
Published in Human molecular genetics (01-08-2016)“…The neurodegenerative disease autosomal recessive spastic ataxia of Charlevoix Saguenay (ARSACS) is caused by loss of function of sacsin, a modular protein…”
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CCG•CGG interruptions in high‐penetrance SCA8 families increase RAN translation and protein toxicity
Published in EMBO molecular medicine (08-11-2021)“…Spinocerebellar ataxia type 8 (SCA8), a dominantly inherited neurodegenerative disorder caused by a CTG•CAG expansion, is unusual because most individuals that…”
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Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization
Published in Cell reports (Cambridge) (01-11-2022)“…Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is a childhood-onset cerebellar ataxia caused by mutations in SACS, which encodes the…”
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The effect of cysteine-containing peptides released during meat digestion on iron absorption in humans
Published in The American journal of clinical nutrition (01-01-1986)“…In order to investigate the constituents responsible for the enhancing effect of meat on intestinal iron absorption in humans, two different types of peptic…”
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Increased lipopolysaccharide‐induced tumour necrosis factor levels and death in hypercholesterolaemic rabbits
Published in Clinical and experimental immunology (01-08-1995)“…SUMMARY Nutritional‐induced hypercholesterolaemia in New Zealand rabbits causes increased susceptibility to experimental infections. Rabbits fed cholesterol…”
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Oncometabolite induced primary cilia loss in pheochromocytoma
Published in Endocrine-related cancer (01-01-2019)“…Primary cilia are sensory organelles involved in regulation of cellular signaling. Cilia loss is frequently observed in tumors; yet, the responsible mechanisms…”
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A modified colorimetric method for the measurement of phagocytosis and antibody-dependent cell cytotoxicity using 2,7-diaminofluorene
Published in Journal of immunological methods (06-07-1992)“…A sensitive and rapid colorimetric method for the in vitro determination of phagocytic activity and antibody-dependent cell-mediated cytotoxicity (ADCC) is…”
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Effects of Ajoene on Lymphocyte and Macrophage Membrane-Dependent Functions
Published in Immunopharmacology and immunotoxicology (01-01-1997)“…Abstract Ajoene, (E,Z) -4,5,9-trithiadeca-1,6,11-triene 9 oxide, is a compound originally isolated from ethanolic extracts of garlic that impairs platelet…”
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ABO-haemolytic disease of the newborn (ABO-HDN): factors influencing its severity and incidence in Venezuela
Published in Journal of tropical pediatrics (1980) (01-02-1995)“…The objective of this study was to determine the incidence of the Haemolytic Disease of the Newborn due to ABO blood group incompatibility (ABO-HDN) in the…”
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Enzyme-linked immunosorbent assay for the detection of substances that carry blood group A specificity
Published in Transfusion (Philadelphia, Pa.) (01-09-1992)“…An enzyme-linked immunosorbent assay (ELISA) was developed to estimate the amount of material carrying blood group A activity in biologic samples. A soluble…”
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Evaluation of complement activity by an enzyme immunoassay
Published in International archives of allergy and immunology (01-01-1993)“…An ELISA-type assay useful for the evaluation of the complement activity in serum is described. Aggregated pooled human IgG (IgGn) prepared so as to exclude…”
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Treatment of ABO hemolytic disease with synthetic blood group trisaccharides
Published in Vox sanguinis (01-01-1994)“…Thirteen infants, 10 with A-O and 3 with B-O hemolytic disease of the newborn (ABO-HDN), were treated with synthetic A or B blood group trisaccharides (ATS,…”
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Preliminary human study of synthetic trisaccharide representing blood substance A
Published in Transplantation proceedings (01-12-1987)Get more information
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