Search Results - "Romano, Adele"

Therapeutic Potential of Targeting the Oxytocinergic System by Romano, Adele, Provensi, Gustavo

“…The nine amino acid neuropeptide oxytocin (OXT, Cys–Tyr–Ile–Gln–Asn–Cys–Pro–Leu–Gly–NH2) is one of the most studied hormones of the body [...]…”
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Cannabinoid Receptor 2 Signaling in Neurodegenerative Disorders: From Pathogenesis to a Promising Therapeutic Target by Cassano, Tommaso, Calcagnini, Silvio, Pace, Lorenzo, De Marco, Federico, Romano, Adele, Gaetani, Silvana

“…As a consequence of an increasingly aging population, the number of people affected by neurodegenerative disorders, such as Alzheimer's disease, Parkinson's…”
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Targeting the Oxytocinergic System: A Possible Pharmacological Strategy for the Treatment of Inflammation Occurring in Different Chronic Diseases by Friuli, Marzia, Eramo, Barbara, Valenza, Marta, Scuderi, Caterina, Provensi, Gustavo, Romano, Adele

“…Unresolved inflammation represents a central feature of different human pathologies including neuropsychiatric, cardiovascular, and metabolic diseases. The…”
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Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review by Di Giacomo, Silvia, Percaccio, Ester, Gullì, Marco, Romano, Adele, Vitalone, Annabella, Mazzanti, Gabriela, Gaetani, Silvana, Di Sotto, Antonella

“…Alzheimer's disease (AD) is a progressive degenerative disorder of the central nervous system, characterized by neuroinflammation, neurotransmitter deficits,…”
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The role of endocannabinoid signaling in the molecular mechanisms of neurodegeneration in Alzheimer's disease by Bedse, Gaurav, Romano, Adele, Lavecchia, Angelo M, Cassano, Tommaso, Gaetani, Silvana

“…Alzheimer's disease (AD) is the most common form of progressive neurodegenerative disease characterized by cognitive impairment and mental disorders. The…”
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Oxytocin and Fear Memory Extinction: Possible Implications for the Therapy of Fear Disorders? by Baldi, Elisabetta, Costa, Alessia, Rani, Barbara, Passani, Maria Beatrice, Blandina, Patrizio, Romano, Adele, Provensi, Gustavo

“…Several psychiatric conditions such as phobias, generalized anxiety, and post-traumatic stress disorder (PTSD) are characterized by pathological fear and…”
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The role of autophagy in Parkinson's disease: a gender difference overview by Cucinotta, Laura, Mannino, Deborah, Filippone, Alessia, Romano, Adele, Esposito, Emanuela, Paterniti, Irene

“…Recent studies have demonstrated dysregulation of the autophagy pathway in patients with Parkinson's disease (PD) and in animal models of PD, highlighting its…”
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Autophagy and inflammation an intricate affair in the management of obesity and metabolic disorders: evidence for novel pharmacological strategies? by Friuli, Marzia, Sepe, Christian, Panza, Elisabetta, Travelli, Cristina, Paterniti, Irene, Romano, Adele

“…Unhealthy lifestyle habits including a sedentary life, the lack of physical activity, and wrong dietary habits are the major ones responsible for the constant…”
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Satiety factor oleoylethanolamide recruits the brain histaminergic system to inhibit food intake by Provensi, Gustavo, Coccurello, Roberto, Umehara, Hayato, Munari, Leonardo, Giacovazzo, Giacomo, Galeotti, Nicoletta, Nosi, Daniele, Gaetani, Silvana, Romano, Adele, Moles, Anna, Blandina, Patrizio, Passani, Maria Beatrice

“…Key factors driving eating behavior are hunger and satiety, which are controlled by a complex interplay of central neurotransmitter systems and peripheral…”
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From Autism to Eating Disorders and More: The Role of Oxytocin in Neuropsychiatric Disorders by Romano, Adele, Tempesta, Bianca, Micioni Di Bonaventura, Maria Vittoria, Gaetani, Silvana

“…Oxytocin (oxy) is a pituitary neuropeptide hormone synthesized from the paraventricular and supraoptic nuclei within the hypothalamus. Like other…”
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Oleoylethanolamide decreases frustration stress-induced binge-like eating in female rats: a novel potential treatment for binge eating disorder by Romano, Adele, Micioni Di Bonaventura, Maria Vittoria, Gallelli, Cristina Anna, Koczwara, Justyna Barbara, Smeets, Dorien, Giusepponi, Maria Elena, De Ceglia, Marialuisa, Friuli, Marzia, Micioni Di Bonaventura, Emanuela, Scuderi, Caterina, Vitalone, Annabella, Tramutola, Antonella, Altieri, Fabio, Lutz, Thomas A, Giudetti, Anna Maria, Cassano, Tommaso, Cifani, Carlo, Gaetani, Silvana

“…Binge eating disorder (BED) is the most frequent eating disorder, for which current pharmacotherapies show poor response rates and safety concerns, thus…”
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PDIA3 Expression Is Altered in the Limbic Brain Regions of Triple-Transgenic Mouse Model of Alzheimer's Disease by Cassano, Tommaso, Giamogante, Flavia, Calcagnini, Silvio, Romano, Adele, Lavecchia, Angelo Michele, Inglese, Francesca, Paglia, Giuliano, Bukke, Vidyasagar Naik, Romano, Antonino Davide, Friuli, Marzia, Altieri, Fabio, Gaetani, Silvana

“…In the present study, we used a mouse model of Alzheimer's disease (AD) (3×Tg-AD mice) to longitudinally analyse the expression level of PDIA3, a protein…”
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Pharmacological Treatment of Depression in Alzheimer’s Disease: A Challenging Task by Cassano, Tommaso, Calcagnini, Silvio, Carbone, Antonio, Bukke, Vidyasagar Naik, Orkisz, Stanislaw, Villani, Rosanna, Romano, Adele, Avolio, Carlo, Gaetani, Silvana

“…Besides the memory impairment, Alzheimer’s disease (AD) is often complicated by neuropsychiatric symptoms also known as behavioral and psychological symptoms…”
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Alterations of Clock Gene RNA Expression in Brain Regions of a Triple Transgenic Model of Alzheimer's Disease by Bellanti, Francesco, Iannelli, Giuseppina, Blonda, Maria, Tamborra, Rosanna, Villani, Rosanna, Romano, Adele, Calcagnini, Silvio, Mazzoccoli, Gianluigi, Vinciguerra, Manlio, Gaetani, Silvana, Giudetti, Anna Maria, Vendemiale, Gianluigi, Cassano, Tommaso, Serviddio, Gaetano

“…A disruption to circadian rhythmicity and the sleep/wake cycle constitutes a major feature of Alzheimer's disease (AD). The maintenance of circadian…”
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The Role of Brain Cholesterol and its Oxidized Products in Alzheimer's Disease by Giudetti, Anna Maria, Romano, Adele, Lavecchia, Angelo Michele, Gaetani, Silvana

“…The human brain is the most cholesterol-rich organ harboring 25% of the total cholesterol pool of the whole body. Cholesterol present in the central nervous…”
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Underlying Susceptibility to Eating Disorders and Drug Abuse: Genetic and Pharmacological Aspects of Dopamine D4 Receptors by Botticelli, Luca, Micioni Di Bonaventura, Emanuela, Del Bello, Fabio, Giorgioni, Gianfabio, Piergentili, Alessandro, Romano, Adele, Quaglia, Wilma, Cifani, Carlo, Micioni Di Bonaventura, Maria Vittoria

“…The dopamine D4 receptor (DRD4) has a predominant expression in the prefrontal cortex (PFC), brain area strictly involved in the modulation of reward processes…”
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Glutamatergic alterations and mitochondrial impairment in a murine model of Alzheimer disease by Cassano, Tommaso, Serviddio, Gaetano, Gaetani, Silvana, Romano, Adele, Dipasquale, Pasqua, Cianci, Silvia, Bellanti, Francesco, Laconca, Leonardo, Romano, Antonino Davide, Padalino, Iolanda, LaFerla, Frank M, Nicoletti, Ferdinando, Cuomo, Vincenzo, Vendemiale, Gianluigi

“…Abstract Deficits in glutamate neurotransmission and mitochondrial functions were detected in the frontal cortex (FC) and hippopcampus (HIPP) of aged…”
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Modulation of the Oxidative Stress and Lipid Peroxidation by Endocannabinoids and Their Lipid Analogues by Gallelli, Cristina Anna, Calcagnini, Silvio, Romano, Adele, Koczwara, Justyna Barbara, de Ceglia, Marialuisa, Dante, Donatella, Villani, Rosanna, Giudetti, Anna Maria, Cassano, Tommaso, Gaetani, Silvana

“…Growing evidence supports the pivotal role played by oxidative stress in tissue injury development, thus resulting in several pathologies including…”
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Amygdalar neurotransmission alterations in the BTBR mice model of idiopathic autism by Bove, Maria, Palmieri, Maria Adelaide, Santoro, Martina, Agosti, Lisa Pia, Gaetani, Silvana, Romano, Adele, Dimonte, Stefania, Costantino, Giuseppe, Sikora, Vladyslav, Tucci, Paolo, Schiavone, Stefania, Morgese, Maria Grazia, Trabace, Luigia

“…Autism Spectrum Disorders (ASD) are principally diagnosed by three core behavioural symptoms, such as stereotyped repertoire, communication impairments and…”
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Chronic Oleoylethanolamide Treatment Decreases Hepatic Triacylglycerol Level in Rat Liver by a PPARγ/SREBP-Mediated Suppression of Fatty Acid and Triacylglycerol Synthesis by Romano, Adele, Friuli, Marzia, Del Coco, Laura, Longo, Serena, Vergara, Daniele, Del Boccio, Piero, Valentinuzzi, Silvia, Cicalini, Ilaria, Fanizzi, Francesco P, Gaetani, Silvana, Giudetti, Anna M

“…Oleoylethanolamide (OEA) is a naturally occurring bioactive lipid belonging to the family of N-acylethanolamides. A variety of beneficial effects have been…”
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