Search Results - "Romaniuk, Aleksandra"
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Biologically synthesized of Au/Pt/ZnO nanoparticles using Arctium lappa extract and cytotoxic activity against leukemia
Published in Biomedical microdevices (01-12-2020)“…The main objective of this work was to assess the cytotoxic activity of Au/Pt/ZnO nanoparticles synthesized using Arctium lappa extract against leukemia. The…”
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Telomerase Inhibitor TMPyP4 Alters Adhesion and Migration of Breast-Cancer Cells MCF7 and MDA-MB-231
Published in International journal of molecular sciences (30-05-2019)“…Human telomeres were one of the first discovered and characterized sequences forming quadruplex structures. Association of these structures with oncogenic and…”
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Facile synthesis of Au/ZnO/Ag nanoparticles using Glechoma hederacea L. extract, and their activity against leukemia
Published in Biomedical microdevices (01-03-2021)“…Metal combinations have been attracting the attention of scientists for some time. They usually exhibit new characteristics that are different from the ones…”
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4
Impact of PKCε downregulation on autophagy in glioblastoma cells
Published in BMC cancer (13-02-2018)“…Several efforts have been focused on identification of pathways involved in malignancy, progression, and response to treatment in Glioblastoma (GB)…”
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Anti-Leukemia Activity of Au/CuO/ZnO Nanoparticles Synthesized used Verbena officinalis Extract
Published in Journal of inorganic and organometallic polymers and materials (2021)“…As biological synthesis has become an alternative to chemical and physical methods for synthesizing nanoparticles, this work describes the synthesis of…”
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Cytotoxic Effect of Phenylethanoid Glycosides Isolated from Plantago lanceolata L
Published in Life (Basel, Switzerland) (16-02-2023)“…The aim of the study is to investigate whether the bioactive compounds isolated from inflorescences, namely, phenylethanoid glucosides, acteoside,…”
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LEP (−2548G>A LEP) and LEPR (223Gln>Arg, 109Lys>Arg) polymorphisms as breast cancer risk factors in the Polish female population
Published in Molecular biology reports (01-04-2021)“…On a global scale, breast cancer is the most common type of cancer in women, and it is still a growing problem. Therefore, new prognostic or diagnostic markers…”
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hTERT Downregulation Attenuates Resistance to DOX, Impairs FAK-Mediated Adhesion, and Leads to Autophagy Induction in Breast Cancer Cells
Published in Cells (Basel, Switzerland) (10-04-2021)“…Telomerase is known to contribute to telomere maintenance and to provide cancer cell immortality. However, numerous reports are showing that the function of…”
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Synergistic antitumor effect of liposomal-based formulations of olaparib and topotecan in primary epithelial ovarian cancer cells
Published in Cancer cell international (12-08-2024)“…Olaparib is a PARP inhibitor inducing synthetic lethality in tumors with deficient homologous recombination (HRD) caused by BRCA1/2 mutations. The FDA has…”
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Evaluation of biological synthesized platinum nanoparticles using Ononidis radix extract on the cell lung carcinoma A549
Published in Biomedical microdevices (01-09-2019)“…Due to the search for new methods for synthesizing nanomaterials, this work proposes the biological synthesis of platinum nanoparticles using Ononidis radix…”
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Telomerase modulation in therapeutic approach
Published in Current pharmaceutical design (01-01-2014)“…Telomerase is a specialized enzymatic complex responsible for the synthesis of telomeric repeats 5'-TTAGGG-3' localized at the ends of eukaryotic chromosomes…”
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Cytotoxic effects of kinetin riboside and its selected analogues on cancer cell lines
Published in Bioorganic & medicinal chemistry letters (01-03-2024)“…[Display omitted] •Seven analogues of kinetin riboside (KR) were synthesized.•KR and its analogues were examined for cytotoxicity against five cancer cell…”
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Proapoptotic and proautophagic activity of 20-hydroxyecdysone in breast cancer cells in vitro
Published in Chemico-biological interactions (01-06-2021)“…The present study was designed to identify the biological activity of three ecdysones, i.e., 20-hydroxyecdysone (20-HE), ajugasterone C, and polypodine B…”
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Breast Cancer Stem Cells and Tumor Heterogeneity: Characteristics and Therapeutic Strategies
Published in Cancers (07-07-2024)“…Breast cancer is one of the most frequently detected malignancies worldwide. It is responsible for more than 15% of all death cases caused by cancer in women…”
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Rosmarinic acid 4′-O-β-glucoside – A compound with prospective medicinal and cosmetological applications - its isolation from callus and root cultures of Eryngium species and biological activity
Published in Industrial crops and products (01-03-2023)“…The goal of the studies was to check if biomass from in vitro cultures of certain Eryngium species could be a source of rosmarinic acid glucoside, which is…”
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16
Resilience, anxiety, depression, and life satisfaction in women suffering from endometriosis: a mediation model
Published in Psychology, health & medicine (21-10-2023)“…The main goal of this cross-sectional study was to assess the relationship between resilience and life satisfaction in women suffering from endometriosis and…”
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Telomerase and drug resistance in cancer
Published in Cellular and molecular life sciences : CMLS (01-11-2017)“…It is well known that a decreased expression or inhibited activity of telomerase in cancer cells is accompanied by an increased sensitivity to some drugs…”
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Mucoadhesive Chitosan Delivery System with Chelidonii Herba Lyophilized Extract as a Promising Strategy for Vaginitis Treatment
Published in Journal of clinical medicine (22-04-2020)“…(also known as celandine) contains pharmacologically active compounds such as isoquinoline alkaloids (e.g., chelidonine, sanguinarine), flavonoids, saponins,…”
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Zapotin (5,6,2′,6′-tetramethoxyflavone) Modulates the Crosstalk Between Autophagy and Apoptosis Pathways in Cancer Cells with Overexpressed Constitutively Active PKCϵ
Published in Nutrition and cancer (17-02-2016)“…Autophagy is important in the regulation of survival and death signaling pathways in cancer. PKCϵ revealed high transforming potential and the ability to…”
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The non-canonical functions of telomerase: to turn off or not to turn off
Published in Molecular biology reports (01-02-2019)“…Telomerase is perceived as an immortality enzyme that enables passing the Hayflick limit. Its main function is telomere restoration but only in a limited group…”
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