Search Results - "Romania, P."
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Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy
Published in Cell death and differentiation (01-05-2012)“…Cancer stem cell (SC) chemoresistance may be responsible for the poor clinical outcome of non-small-cell lung cancer (NSCLC) patients. In order to identify the…”
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The Vici syndrome protein EPG5 regulates intracellular nucleic acid trafficking linking autophagy to innate and adaptive immunity
Published in Autophagy (02-01-2018)“…Vici syndrome is a human inherited multi-system disorder caused by recessive mutations in EPG5, encoding the EPG5 protein that mediates the fusion of…”
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miRNA let-7c promotes granulocytic differentiation in acute myeloid leukemia
Published in Oncogene (01-08-2013)“…MicroRNAs (miRNAs), small non-coding RNAs that regulate gene expression post-transcriptionally, are involved in many complex cellular processes. Several miRNAs…”
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Identification of a Genetic Variation in ERAP1 Aminopeptidase that Prevents Human Cytomegalovirus miR-UL112-5p-Mediated Immunoevasion
Published in Cell reports (Cambridge) (25-07-2017)“…Herein, we demonstrate that HCMV miR-UL112-5p targets ERAP1, thereby inhibiting the processing and presentation of the HCMV pp65495-503 peptide to specific…”
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Overexpression of Ets-1 in human hematopoietic progenitor cells blocks erythroid and promotes megakaryocytic differentiation
Published in Cell death and differentiation (01-07-2006)“…Ets-1 is a widely expressed transcription factor implicated in development, tumorigenesis and hematopoiesis. We analyzed Ets-1 gene expression during human…”
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Transcriptional silencing of the ETS1 oncogene contributes to human granulocytic differentiation
Published in Haematologica (Roma) (01-10-2010)“…Ets-1 is a widely expressed transcription factor implicated in several biological processes including hematopoiesis, where it contributes to the regulation of…”
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Endoplasmic reticulum aminopeptidase 1 function and its pathogenic role in regulating innate and adaptive immunity in cancer and major histocompatibility complex class I-associated autoimmune diseases
Published in Tissue antigens (01-08-2014)“…Major histocompatibility complex (MHC) class I molecules present antigenic peptides on the cell surface to alert natural killer (NK) cells and CD8+ T cells for…”
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Abstract P4-01-19: Liquid biopsy and re-biopsy: Tracking mutational trajectories in HER2+ breast cancer patients undergoing T-DM1 treatment
Published in Cancer research (Chicago, Ill.) (15-02-2019)“…Abstract Background: The antibody-drug conjugate Trastuzumab emtansine (T-DM1, Kadcyla®) is standard of care in HER2+ breast cancer patients on clinical…”
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MicroRNA 223-dependent expression of LMO2 regulates normal erythropoiesis
Published in Haematologica (Roma) (01-04-2009)“…1 Department of Hematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome 2 IRCCS MultiMedica, Milan, Italy Correspondence: Nadia Felli,…”
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Epigenetic deregulation of microRNAs in rhabdomyosarcoma and neuroblastoma and translational perspectives
Published in International journal of molecular sciences (05-12-2012)“…Gene expression control mediated by microRNAs and epigenetic remodeling of chromatin are interconnected processes often involved in feedback regulatory loops,…”
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Bound single-particle states and scattering of nucleons on spherical nuclei with a global optical model
Published in Physical review. C, Nuclear physics (01-10-2007)“…We present a global spherical optical model for nucleons with incident energies up to 200 MeV containing dispersive terms and a local energy approximation…”
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