Search Results - "Romana Mauro, Francesca"

ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression by GUARINI, Anna, MARINELLI, Marilisa, NANNI, Mauro, DEL GIUDICE, Ilaria, ROMANA MAURO, Francesca, TORRENTE, Isabella, FOA, Robin, TAVOLARO, Simona, BELLACCHIO, Emanuele, MAGLIOZZI, Monia, CHIARETTI, Sabina, DE PROPRIS, Maria Stefania, PERAGINE, Nadia, SANTANGELO, Simona, PAOLONI, Francesca

“…The genetic characterization of chronic lymphocytic leukemia cells correlates with the behavior, progression and response to treatment of the disease. Our aim…”
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White blood cell count at diagnosis and immunoglobulin variable region gene mutations are independent predictors of treatment-free survival in young patients with stage A chronic lymphocytic leukemia by DEL GIUDICE, Ilaria, ROMANA MAURO, Francesca, ARMIENTO, Daniele, PAOLONI, Francesca, GUARINI, Anna, FOA, Robin, STEFANIA DE PROPRIS, Maria, SANTANGELO, Simona, MARINELLI, Marilisa, PERAGINE, Nadia, DI MAIO, Valeria, NANNI, Mauro, BARZOTTI, Rita, MANCINI, Francesca

“…A comprehensive panel of clinical-biological parameters was prospectively evaluated at presentation in 112 patients with chronic lymphocytic leukemia (<65…”
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The complex karyotype landscape in chronic lymphocytic leukemia allows the refinement of the risk of Richter syndrome transformation by Visentin, Andrea, Bonaldi, Laura, Rigolin, Gian Matteo, Mauro, Francesca Romana, Martines, Annalisa, Frezzato, Federica, Pravato, Stefano, Gargarella, Leila Romano, Bardi, Maria Antonella, Cavallari, Maurizio, Volta, Eleonora, Cavazzini, Francesco, Nanni, Mauro, Facco, Monica, Piazza, Francesco, Guarini, Anna, Foà, Robin, Semenzato, Gianpietro, Cuneo, Antonio, Trentin, Livio

“…Complex karyotype (CK) at chronic lymphocytic leukemia (CLL) diagnosis is a negative biomarker of adverse outcome. Since the impact of CK and its subtypes,…”
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HIF-1α is over-expressed in leukemic cells from TP53 -disrupted patients and is a promising therapeutic target in chronic lymphocytic leukemia by Griggio, Valentina, Vitale, Candida, Todaro, Maria, Riganti, Chiara, Kopecka, Joanna, Salvetti, Chiara, Bomben, Riccardo, Bo, Michele Dal, Magliulo, Daniela, Rossi, Davide, Pozzato, Gabriele, Bonello, Lisa, Marchetti, Monia, Omedè, Paola, Kodipad, Ahad Ahmed, Laurenti, Luca, Del Poeta, Giovanni, Mauro, Francesca Romana, Bernardi, Rosa, Zenz, Thorsten, Gattei, Valter, Gaidano, Gianluca, Foà, Robin, Massaia, Massimo, Boccadoro, Mario, Coscia, Marta

“…In chronic lymphocytic leukemia (CLL), the hypoxia-inducible factor 1 (HIF-1) regulates the response of tumor cells to hypoxia and their protective…”
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Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia by Fulci, Valerio, Chiaretti, Sabina, Goldoni, Marina, Azzalin, Gianluca, Carucci, Nicoletta, Tavolaro, Simona, Castellano, Leandro, Magrelli, Armando, Citarella, Franca, Messina, Monica, Maggio, Roberta, Peragine, Nadia, Santangelo, Simona, Mauro, Francesca Romana, Landgraf, Pablo, Tuschl, Thomas, Weir, David B., Chien, Minchen, Russo, James J., Ju, Jingyue, Sheridan, Robert, Sander, Chris, Zavolan, Mihaela, Guarini, Anna, Foà, Robin, Macino, Giuseppe

“…MicroRNAs (miRNAs) are a novel class of small noncoding RNAs that modulate the expression of genes at the posttranscriptional level. These small molecules have…”
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Risk of hepatitis B virus reactivation in chronic lymphocytic leukemia patients receiving ibrutinib with or without antiviral prophylaxis. A retrospective multicentric GIMEMA study by Innocenti, Idanna, Reda, Gianluigi, Visentin, Andrea, Coscia, Marta, Motta, Marina, Murru, Roberta, Moia, Riccardo, Gentile, Massimo, Pennese, Elsa, Quaglia, Francesca Maria, Albano, Francesco, Cassin, Ramona, Deodato, Marina, Ielo, Claudia, Frustaci, Anna Maria, Piciocchi, Alfonso, Rughini, Arianna, Arena, Valentina, Di Sevo, Daniela, Tomasso, Annamaria, Autore, Francesco, Del Poeta, Giovanni, Scarfò, Lydia, Mauro, Francesca Romana, Tedeschi, Alessandra, Trentin, Livio, Pompili, Maurizio, Foà, Robin, Ghia, Paolo, Cuneo, Antonio, Laurenti, Luca

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Use of BTK inhibitors with focus on ibrutinib in mantle cell lymphoma: An expert panel opinion statement by Zinzani, Pier Luigi, Martelli, Maurizio, Ferrero, S., Gentile, Massimo, Laurenti, Luca, Romana Mauro, Francesca, Sportoletti, Paolo, Tedeschi, Alessandra, Varettoni, M., Visco, Carlo

“…The introduction of Bruton's tyrosine kinase (BTK) inhibitors transformed the management of patients with mantle cell lymphoma (MCL). Ibrutinib, the…”
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Treatment with ibrutinib does not induce a TP53 clonal evolution in chronic lymphocytic leukemia by Cafforio, Luciana, Raponi, Sara, Cappelli, Luca Vincenzo, Ilari, Caterina, Soscia, Roberta, De Propris, Maria Stefania, Mariglia, Paola, Rigolin, Gian Matteo, Bardi, Antonella, Peragine, Nadia, Piciocchi, Alfonso, Arena, Valentina, Mauro, Francesca Romana, Cuneo, Antonio, Guarini, Anna, Foa, Robin, Del Giudice, Ilaria

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Modulated expression of adhesion, migration and activation molecules may predict the degree of response in chronic lymphocytic leukemia patients treated with ibrutinib plus rituximab by Peragine, Nadia, De Propris, Maria Stefania, Intoppa, Stefania, Milani, Maria Laura, Mariglia, Paola, Mauro, Francesca Romana, Raponi, Sara, Soddu, Stefano, Cuneo, Antonio, Rigolin, Gian Matteo, Del Giudice, Ilaria, Foà, Robin, Guarini, Anna

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Efficacy of bendamustine and rituximab as first salvage treatment in chronic lymphocytic leukemia and indirect comparison with ibrutinib: a GIMEMA, ERIC and UK CLL FORUM study by Cuneo, Antonio, Follows, George, Rigolin, Gian Matteo, Piciocchi, Alfonso, Tedeschi, Alessandra, Trentin, Livio, Perez, Angeles Medina, Coscia, Marta, Laurenti, Luca, Musuraca, Gerardo, Farina, Lucia, Delgado, Alfredo Rivas, Orlandi, Ester Maria, Galieni, Piero, Mauro, Francesca Romana, Visco, Carlo, Amendola, Angela, Billio, Atto, Marasca, Roberto, Chiarenza, Annalisa, Meneghini, Vittorio, Ilariucci, Fiorella, Marchetti, Monia, Molica, Stefano, Re, Francesca, Gaidano, Gianluca, Gonzalez, Marcos, Forconi, Francesco, Ciolli, Stefania, Cortelezzi, Agostino, Montillo, Marco, Smolej, Lukas, Schuh, Anna, Eyre, Toby A, Kennedy, Ben, Bowles, Kris M, Vignetti, Marco, de la Serna, Javier, Moreno, Carol, Foà, Robin, Ghia, Paolo

“…We performed an observational study on the efficacy of ben-damustine and rituximab (BR) as first salvage regimen in chronic lymphocytic leukemia (CLL). In an…”
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A Retrospective Study on the Efficacy of Subcutaneous Immunoglobulin as Compared to Intravenous Formulation in Patients with Chronic Lymphocytic Leukemia and Secondary Antibody Deficiency by Visentin, Andrea, Molinari, Maria Chiara, Pravato, Stefano, Cellini, Alessandro, Angotzi, Francesco, Cavaretta, Chiara Adele, Ruocco, Valeria, Imbergamo, Silvia, Piazza, Francesco, Proietti, Giulia, Mauro, Francesca Romana, Trentin, Livio

“…Secondary antibody deficiency (SAD) is a common complication in chronic lymphocytic leukemia (CLL) which favors the development of life-threatening infections…”
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TH2/TH1 Shift Under Ibrutinib Treatment in Chronic Lymphocytic Leukemia by Puzzolo, Maria Cristina, Del Giudice, Ilaria, Peragine, Nadia, Mariglia, Paola, De Propris, Maria Stefania, Cappelli, Luca Vincenzo, Trentin, Livio, Reda, Gianluigi, Cuneo, Antonio, Molica, Stefano, Piciocchi, Alfonso, Arena, Valentina, Mauro, Francesca Romana, Guarini, Anna, Foà, Robin

“…Ibrutinib may revert the T-helper (Th)2 polarization observed in chronic lymphocytic leukemia (CLL) by targeting the IL-2-inducible kinase, that shows a…”
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Obinutuzumab plus chlorambucil versus ibrutinib in previously untreated chronic lymphocytic leukemia patients without TP53 disruptions: A real-life CLL campus study by Visentin, Andrea, Mauro, Francesca Romana, Catania, Gioachino, Fresa, Alberto, Vitale, Candida, Sanna, Alessandro, Mattiello, Veronica, Cibien, Francesca, Sportoletti, Paolo, Gentile, Massimo, Rigolin, Gian Matteo, Quaglia, Francesca Maria, Murru, Roberta, Gozzetti, Alessandro, Molica, Stefano, Marchetti, Monia, Pravato, Stefano, Angotzi, Francesco, Cellini, Alessandro, Scarfò, Lydia, Reda, Gianluigi, Coscia, Marta, Laurenti, Luca, Ghia, Paolo, Foà, Robin, Cuneo, Antonio, Trentin, Livio

“…One of the main issues in the treatment of patients with chronic lymphocytic leukemia (CLL) deals with the choice between continuous or fixed-duration therapy…”
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BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells by Guarini, Anna, Chiaretti, Sabina, Tavolaro, Simona, Maggio, Roberta, Peragine, Nadia, Citarella, Franca, Ricciardi, Maria Rosaria, Santangelo, Simona, Marinelli, Marilisa, De Propris, Maria Stefania, Messina, Monica, Mauro, Francesca Romana, Del Giudice, Ilaria, Foà, Robert

“…Chronic lymphocytic leukemia (CLL) patients exhibit a variable clinical course. To investigate the association between clinicobiologic features and…”
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What Are the Attributes Prioritized in the Choice of Therapy in Chronic Lymphocytic Leukemia? A Patient‐physician Cross‐matching Analysis of a Discrete Choice Experiment by Laurenti, Luca, Gaidano, Gianluca, Mauro, Francesca Romana, Molica, Stefano, Pasqualetti, Patrizio, Scarfò, Lydia, Ghia, Paolo

“…Several treatment options are available for chronic lymphocytic leukemia (CLL) and, for this reason, treatment choice can result challenging after introducing…”
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Lymphocyte Doubling Time As A Key Prognostic Factor To Predict Time To First Treatment In Early-Stage Chronic Lymphocytic Leukemia by Morabito, Fortunato, Tripepi, Giovanni, Moia, Riccardo, Recchia, Anna Grazia, Boggione, Paola, Mauro, Francesca Romana, Bossio, Sabrina, D’Arrigo, Graziella, Martino, Enrica Antonia, Vigna, Ernesto, Storino, Francesca, Fronza, Gilberto, Di Raimondo, Francesco, Rossi, Davide, Condoluci, Adalgisa, Colombo, Monica, Fais, Franco, Fabris, Sonia, Foa, Robin, Cutrona, Giovanna, Gentile, Massimo, Montserrat, Emili, Gaidano, Gianluca, Ferrarini, Manlio, Neri, Antonino

“…The prognostic role of lymphocyte doubling time (LDT) in chronic lymphocytic leukemia (CLL) was recognized more than three decades ago when the neoplastic…”
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Chlorambucil plus rituximab as front-line therapy for elderly and/or unfit chronic lymphocytic leukemia patients: correlation with biologically-based risk stratification by Laurenti, Luca, Innocenti, Idanna, Autore, Francesco, Ciolli, Stefania, Mauro, Francesca Romana, Mannina, Donato, Del Poeta, Giovanni, D'Arena, Giovanni, Massaia, Massimo, Coscia, Marta, Molica, Stefano, Pozzato, Gabriele, Efremov, Dimitar G, Vannata, Barbara, Marasca, Roberto, Galieni, Pietro, Cuneo, Antonio, Orlando, Sonia, Piciocchi, Alfonso, Boncompagni, Riccardo, Vincelli, Donatella, Liberati, Anna Marina, Russo, Filomena, Foá, Robin

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Spontaneous regression of chronic lymphocytic leukemia: clinical and biologic features of 9 cases by Del Giudice, Ilaria, Chiaretti, Sabina, Tavolaro, Simona, De Propris, Maria Stefania, Maggio, Roberta, Mancini, Francesca, Peragine, Nadia, Santangelo, Simona, Marinelli, Marilisa, Mauro, Francesca Romana, Guarini, Anna, Foà, Robin

“…In chronic lymphocytic leukemia (CLL), spontaneous regressions are an exceptional phenomenon, whose biologic features are unknown. We describe 9 CLL patients…”
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Front-Line Therapy for Elderly Chronic Lymphocytic Leukemia Patients: Bendamustine Plus Rituximab or Chlorambucil Plus Rituximab? Real-Life Retrospective Multicenter Study in the Lazio Region by Autore, Francesco, Innocenti, Idanna, Corrente, Francesco, Del Principe, Maria Ilaria, Rosati, Serena, Falcucci, Paolo, Fresa, Alberto, Conte, Esmeralda, Limongiello, Maria Assunta, Renzi, Daniela, De Padua, Laura, Andriani, Alessandro, Pisani, Francesco, Cimino, Giuseppe, Tafuri, Agostino, Montanaro, Marco, Mauro, Francesca Romana, Del Poeta, Giovanni, Laurenti, Luca

“…Previous studies investigated the efficacy and the safety of bendamustine (B) vs. chlorambucil (Chl) associated with rituximab (R) in fludarabine-ineligible…”
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The coexistence of chronic lymphocytic leukemia and myeloproliperative neoplasms: A retrospective multicentric GIMEMA experience by Laurenti, Luca, Tarnani, Michela, Nichele, Ilaria, Ciolli, Stefania, Cortelezzi, Agostino, Forconi, Francesco, Rossi, Davide, Mauro, Francesca Romana, D'Arena, Giovanni, Del Poeta, Giovanni, Montanaro, Marco, Morabito, Fortunato, Musolino, Caterina, Callea, Vincenzo, Falchi, Lorenzo, Tedeschi, Alessandra, Ambrosetti, Achille, Gaidano, Gianluca, Leone, Giuseppe, Foà, Robin

“…Although the coexistence of chronic lymphocytic leukemia (CLL) and myeloproliferative neoplasms (MPN) has been sporadically reported in the literature, no…”
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