Search Results - "Romakh, L. P."

Effect of Inducers and Inhibitors of the Keap1/Nrf2/ARE System on the Viability and Functional Activity of Model Neuronal-Like and Glial Cells by Menshchikova, E. B., Chechushkov, A. V., Kozhin, P. M., Romakh, L. P., Serykh, A. E., Khrapova, M. V., Petrova, E. S., Kandalintseva, N. V.

“…On mouse neuroblastoma (Neuro-2a) and human glioblastoma (U-87 MG) cell lines, we studied the effect of inducers and inhibitors of redox-sensitive signaling…”
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Protective Effect of a New Monophenolic Antioxidant TS-13 in a Mouse Model of Parkinson’s Disease by Menshchikova, E. B., Khrapova, M. V., Kozhin, P. M., Chechushkov, A. V., Serykh, A. E., Romakh, L. P., Kandalintseva, N. V.

“…The development of means of the prevention and treatment of age-related neurodegenerative diseases, as well as geroprotectors, among other things, is based on…”
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Synthetic antioxidant TS-13 reduces doxorubicin cardiotoxicity by Menshchikova, E. B., Knyazev, R. A., Trifonova, N. V., Deeva, N. A., Kolpakov, A. R., Lidia P. Romakh, L. P., Kandalintseva, N. V.

“…The antitumor antibiotic doxorubicin, a representative of a large group of anthriacyclines, is widely and quite effectively used to treat patients with…”
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Synthetic Antioxidant TS-13 Reduces the Cardiotoxicity of Doxorubicin by Menshchikova, E. B., Knyazev, R. A., Trifonova, N. V., Deeva, N. A., Kolpakov, A. R., Romakh, L. P., Kandalintseva, N. V.

“…The antitumor antibiotic doxorubicin, a member of a large group of anthracyclines, is widely and quite effectively used to treat patients with malignant…”
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Keap1/Nrf2/ARE System Inducers Do Not Increase the Resistance of the Heart to Prolonged Ischemia/Reperfusion by Kozhin, P. M., Sementsov, A. S., Khrapov, S. E., Khrapova, M. V., Romakh, L. P., Kandalintseva, N. V., Menshchikova, E. B.

“…Oxidative stress acts as an important mechanism of myocardial damage during ischemia/reperfusion. To consider the possibility of restoring the redox balance…”
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The Toxicity of a New Monophenolic Synthetic Inducer of Keap1/Nrf2/ARE Redox-Sensitive Signaling System In Vitro and In Vivo by Khrapova, M. V., Khrapov, S. E., Chechushkov, A. V., Kozhin, P. M., Romakh, L. P., Serykh, A. E., Kholshin, S. V., Kandalintseva, N. V., Menshchikova, E. B.

“…Development of “indirect antioxidants” capable of activating redox-sensitive signaling systems, primarily the Keap1/Nrf2/ARE system, is a promising area of…”
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The Keap1/Nrf2/ARE system activators do not increase cardiac resistance to long-term ischemia/reperfusion by Kozhin, P. M., Sementsov, A. S., Khrapov, S. E., Khrapova, M. V., Romakh, L. P., Kandalintseva, N. V., Menshchikova, E. B.

“…Oxidative stress is an important mechanism of myocardial damage during ischemia/reperfusion. To investigate the possibility of restoring the redox balance…”
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Toxicity of new monophenolic synthetic activator of Keap1/Nrf2/ARE redox-sensitive signaling system in vitro and in vivo by Khrapova, M. V., Khrapov, S. E., Chechushkov, A. V., Kozhin, P. M., Romakh, L. P., Serykh, A. E., Kholshin, S. V., Kandalintseva, N. V., Menshchikova, E. B.

“…One of the promising areas of modern pharmacology is the development of «indirect antioxidants» capable of activating redox-sensitive signaling systems,…”
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Increased expression of autophagy and Nrf2-dependent signaling pathway genes by new monophenolic antioxidants depends on their structure by Khrapov, S. E., Kozhin, P. M., Khrapova, M. V., Serykh, A. E., Romakh, L. P., Pavlov, V. S., Chechushkov, A. V., Kholshin, S. V., Zenkov, N. K., Menshchikova, E. B.

“…Under certain conditions, both activators and inhibitors of Nrf2-dependent signaling and autophagy can serve as potential agents for the prevention, treatment,…”
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Effect of new water-soluble phenolic antioxidants on the activity of Nrf2-driven enzymes, glutathione system, and Nrf2 translocation into the nucleus by E. B. Menshchikova, N. K. Zenkov, P. M. Kozhin, A. V. Chechushkov, V. S. Pavlov, L. P. Romakh, M. V. Khrapova, A. E. Serykh, O. B. Gritsyk, N. V. Kandalintseva

“…Understanding the role of reactive oxygen and nitrogen species in eustress (redox balance) and distress (oxidative stress) development poses new challenges for…”
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Study of Antiviral Efficiency of Oxidized Dextrans In Vitro and In Vivo by Kurskaya, O. G., Murashkina, T. A., Alekseev, A. Yu, Sharshov, K. A., Romakh, L. P., Derko, A. A., Troitskii, A. V., Bystrova, T. N., Shkurupy, V. A., Shestopalov, A. M.

“…Antiviral efficiency of oxidized dextrans (OD) with different molecular weights and oxidation degree (OD40min, OD70min, OD40max, and OD70 max) was studied in…”
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