Search Results - "Romagné, F."

Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models by Lhospice, F, Brégeon, D, Belmant, C, Dennler, P, Chiotellis, A, Fischer, E, Gauthier, L, Boëdec, A, Rispaud, H, Savard-Chambard, S, Represa, A, Schneider, N, Paturel, C, Sapet, M, Delcambre, C, Ingoure, S, Viaud, N, Bonnafous, C, Schibli, R, Romagné, F

“…Antibody–drug conjugates (ADCs) have demonstrated clinical benefits that have led to the recent FDA approval of KADCYLA and ADCETRIS. Most ADCs that are…”
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Frequency and Phenotyping of Human Immunodeficiency Virus (HIV)–Specific CD8+ T Cells in HIV-Infected Children, Using Major Histocompatibility Complex Class I Peptide Tetramers by Scott-Algara, Daniel, Buseyne, Florence, Blanche, Stephane, Rouzioux, Christine, Jouanne, C., Romagné, F., Rivière, Yves

“…HLA-A*02 tetramers complexed to human immunodeficiency virus (HIV) Gag SLYNTVATL and HIV Pol ILKEPVHGV peptides were used to characterize HLA class…”
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Relationships between natural T cells, atopy, IgE levels, and IL‐4 production by Magnan, A., Mély, L., Prato, S., Vervloet, D., Romagné, F., Camilla, C., Necker, A., Casano, B., Montero‐Jullian, F., Malissen, B., Bongrand, P., Fert, V.

“…Background: Th2 cells govern allergic disorders. Mechanisms leading to the Th2 commitment are dominated by the requirement of IL‐4. A potential source of this…”
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Recognition of Peptide-MHC Class I Complexes by Activating Killer Immunoglobulin-Like Receptors by Stewart, C. Andrew, Laugier-Anfossi, Fanny, Vély, Frédéric, Saulquin, Xavier, Riedmuller, Jenifer, Tisserant, Agnès, Gauthier, Laurent, Romagné, François, Ferracci, Géraldine, Arosa, Fernando A., Moretta, Alessandro, Sun, Peter D., Ugolini, Sophie, Vivier, Eric, Cresswell, Peter

“…Inhibitory receptors for MHC class I molecules increase the threshold of lymphocyte activation. Natural Killer (NK) cells express a large number of such…”
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Natural Killer Cell Acceptance of H-2 Mismatch Bone Marrow Grafts in Transgenic Mice Expressing HLA-Cw3 Specific Killer Cell Inhibitory Receptor (CD158b) by Cambiaggi, Anna, Verthuy, Christophe, Naquet, Philippe, Romagne, Francois, Ferrier, Pierre, Biassoni, Roberto, Moretta, Alessandro, Moretta, Lorenzo, Vivier, Eric

“…Natural killer (NK) cells express killer cell inhibitory receptors (KIRs) for major histocompatibility complex class I molecules. Engagement of these surface…”
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Chemical synthesis and biological activity of bromohydrin pyrophosphate, a potent stimulator of human gamma delta T cells by Espinosa, E, Belmant, C, Pont, F, Luciani, B, Poupot, R, Romagné, F, Brailly, H, Bonneville, M, Fournié, J J

“…Small phosphorylated metabolites from mycobacteria stimulate human gammadelta T lymphocytes. Although such phosphoantigens could prove useful in the…”
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Frequent Contribution of T Cell Clonotypes with Public TCR Features to the Chronic Response Against a Dominant EBV-Derived Epitope: Application to Direct Detection of Their Molecular Imprint on the Human Peripheral T Cell Repertoire by Lim, Annick, Trautmann, Lydie, Peyrat, Marie-Alix, Couedel, Chrystelle, Davodeau, Francois, Romagne, Francois, Kourilsky, Philippe, Bonneville, Marc

“…In an attempt to provide a global picture of the TCR repertoire diversity of a chronic T cell response against a common Ag, we performed an extensive TCR…”
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Immunoassay for functional human soluble interleukin-6 receptor in plasma based on ligand/receptor interactions by Montero-Julian, F A, Liautard, J, Flavetta, S, Romagné, F, Gaillard, J P, Brochier, J, Klein, B, Brailly, H

“…Soluble forms of most cytokine receptors, able to bind effectively to their respective ligands, have now been described. A soluble interleukin-6-binding…”
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Regulation of Inhibitory and Activating Killer-Cell Ig-Like Receptor Expression Occurs in T Cells After Termination of TCR Rearrangements by Vely, Frederic, Peyrat, Marie-Alix, Couedel, Christelle, Morcet, Jean-Francois, Halary, Franck, Davodeau, Francois, Romagne, Francois, Scotet, Emmanuel, Saulquin, Xavier, Houssaint, Elisabeth, Schleinitz, Nicolas, Moretta, Alessandro, Vivier, Eric, Bonneville, Marc

“…A small fraction of T cells expresses killer-cell Ig-like receptors (KIR), a family of MHC class I-specific receptors that can modulate TCR-dependent…”
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Characterization of CMVpp65-specific CD8+ T lymphocytes using MHC tetramers in kidney transplant patients and healthy participants by ENGSTRAND, M, TOURNAY, C, PEYRAT, M. A, ERIKSSON, B.-M, WADSTRÖM, J, WIRGART, B. Z, ROMAGNE, F, BONNEVILLE, M, TÖTTERMAN, T. H, KORSGREN, O

“…Cytomegalovirus (CMV) is a ubiquitous herpesvirus that infects 50-90% of individuals in different populations. After primary infection, the virus persists…”
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Current and future drugs targeting one class of innate immunity receptors: the Toll-like receptors by Romagne, Francois

“…Innate immunity receptors are germline-encoded receptors that can sense molecular signatures of pathogens and cancer cells. Recent advances in immunology…”
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Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes by Tan, L C, Mowat, A G, Fazou, C, Rostron, T, Roskell, H, Dunbar, P R, Tournay, C, Romagné, F, Peyrat, M A, Houssaint, E, Bonneville, M, Rickinson, A B, McMichael, A J, Callan, M F

“…Epstein-Barr virus (EBV) is transmitted orally, replicates in the oropharynx and establishes life-long latency in human B lymphocytes. T-cell responses to…”
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270 (PB258): Molecular and pharmacological profiling of a prostate cancer PDX panel and in vitro cellular counterparts to identify resistance mechanisms and new therapeutic options by Indersie, E., Sinayen, L., Bigot, L., Gorse, A., Tavernier, M., Ven, E. Le, Friboulet, L., Farace, F., Morgado, E., Pouyet, L., Loriot, Y., Romagne, F., Deas, O.

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Dual T cell receptor beta chain expression on human T lymphocytes by Davodeau, F, Peyrat, M A, Romagné, F, Necker, A, Hallet, M M, Vié, H, Bonneville, M

“…Allelic exclusion of lymphocyte antigen receptor chains has been hypothesized as a mechanism developed by the immune system to ensure efficient lymphocyte…”
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Effects of anti-NKG2A antibody administration on leukemia and normal hematopoietic cells by Ruggeri, Loredana, Urbani, Elena, André, Pascale, Mancusi, Antonella, Tosti, Antonella, Topini, Fabiana, Bléry, Mathieu, Animobono, Lucia, Romagné, François, Wagtmann, Nicolai, Velardi, Andrea

“…Natural killer cells are key cells of the innate immune system. Natural killer cell receptor repertoires are diversified by a stochastic expression of…”
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Alterations of T cell repertoire after bone marrow transplantation: characterization of over-represented subsets by Gaschet, J, Denis, C, Milpied, N, Hallet, M M, Romagné, F, Necker, A, Vivien, R, David-Ameline, J, Davodeau, F, Bonneville, M

“…We recently demonstrated that frequencies of T cell receptor-V (TcR-V)-specific subsets are frequently altered after both allogeneic and autologous BMT. The…”
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Human NK Cell Education by Inhibitory Receptors for MHC Class I by Anfossi, Nicolas, André, Pascale, Guia, Sophie, Falk, Christine S., Roetynck, Sophie, Stewart, C. Andrew, Breso, Violette, Frassati, Coralie, Reviron, Denis, Middleton, Derek, Romagné, François, Ugolini, Sophie, Vivier, Eric

“…Natural killer (NK) cells recognize the absence of self MHC class I as a way to discriminate normal cells from cells in distress. In humans, this “missing…”
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Stimulation of human T cells by streptococcal "superantigen" erythrogenic toxins (scarlet fever toxins) by Braun, MA, Gerlach, D, Hartwig, UF, Ozegowski, JH, Romagne, F, Carrel, S, Kohler, W, Fleischer, B

“…The pyrogenic (erythrogenic) exotoxins A and C (SPEA and SPEC) of Streptococcus pyogenes belong to the family of mitogenic toxins of which the staphylococcal…”
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A versatile method to produce antibodies to human T cell receptor V beta segments: frequency determination of human V beta 2+ T cells that react with toxic-shock syndrome toxin-1 by Romagné, F, Besnardeau, L, Malissen, B

“…Human V beta (hV beta) regions have been expressed in the context of mouse T cell receptor (TcR)-CD3 complexes, and subsequently used to raise hV beta-specific…”
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Repertoire analysis of human peripheral blood lymphocytes using a human V delta 3 region-specific monoclonal antibody. Characterization of dual T cell receptor (TCR) delta-chain expressors and alpha beta T cells expressing V delta 3J alpha C alpha-encoded TCR chains by Peyrat, MA, Davodeau, F, Houde, I, Romagne, F, Necker, A, Leget, C, Cervoni, JP, Cerf- Bensussan, N, Vie, H, Bonneville, M

“…V delta 3 usage and combinatorial expression of V gamma and V delta regions was studied on peripheral T cells with a novel V delta 3-specific mAb (p11.10b),…”
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