Search Results - "Roméo, Paul‐Henri"

Progenitors from the central nervous system drive neurogenesis in cancer by Mauffrey, Philippe, Tchitchek, Nicolas, Barroca, Vilma, Bemelmans, Alexis-Pierre, Firlej, Virginie, Allory, Yves, Roméo, Paul-Henri, Magnon, Claire

“…Autonomic nerve fibres in the tumour microenvironment regulate cancer initiation and dissemination, but how nerves emerge in tumours is currently unknown. Here…”
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Metabolomics for rheumatic diseases: has the time come? by Semerano, Luca, Roméo, Paul-Henri, Boissier, Marie-Christophe

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Red blood cell metabolomics identify ergothioneine as a key metabolite in DMARD-naïve rheumatoid arthritis and response to methotrexate by Sigaux, Johanna, Junot, Christophe, Boissier, Marie-Christophe, Petit, Mylène, Breckler, Magali, Castelli, Florence, Fenaille, François, Roméo, Paul-Henri, Semerano, Luca

“…Using a new red blood cell (RBC) metabolite extraction protocol, we performed a metabolomic analysis on RBCs in rheumatoid arthritis (RA) patients treated or…”
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Prion protein deficiency impairs hematopoietic stem cell determination and sensitizes myeloid progenitors to irradiation by Siberchicot, Capucine, Gault, Nathalie, Déchamps, Nathalie, Barroca, Vilma, Aguzzi, Adriano, Roméo, Paul-Henri, Radicella, J Pablo, Bravard, Anne, Bernardino-Sgherri, Jacqueline

“…Highly conserved among species and expressed in various types of cells, numerous roles have been attributed to the cellular prion protein (PrPC). In…”
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In vivo cellular imaging pinpoints the role of reactive oxygen species in the early steps of adult hematopoietic reconstitution by Lewandowski, Daniel, Barroca, Vilma, Ducongé, Frédéric, Bayer, Jan, Van Nhieu, Jeanne Tran, Pestourie, Carine, Fouchet, Pierre, Tavitian, Bertrand, Roméo, Paul-Henri

“…Few techniques are available to characterize in vivo the early cellular dynamics of long-term reconstitution of hematopoiesis after transplantation of…”
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KLF4 inhibition promotes the expansion of keratinocyte precursors from adult human skin and of embryonic-stem-cell-derived keratinocytes by Fortunel, Nicolas O., Chadli, Loubna, Coutier, Julien, Lemaître, Gilles, Auvré, Frédéric, Domingues, Sophie, Bouissou-Cadio, Emmanuelle, Vaigot, Pierre, Cavallero, Sophie, Deleuze, Jean-François, Roméo, Paul-Henri, Martin, Michèle T.

“…Expanded autologous skin keratinocytes are currently used in cutaneous cell therapy, and embryonic-stem-cell-derived keratinocytes could become a complementary…”
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Dendritic Cells Can Turn CD4+ T Lymphocytes into Vascular Endothelial Growth Factor-Carrying Cells by Intercellular Neuropilin-1 Transfer by Bourbie-Vaudaine, Sarah, Blanchard, Nicolas, Hivroz, Claire, Romeo, Paul-Henri

“…Neuropilin-1 (NRP1) is a transmembrane protein expressed on neuronal and endothelial cells where it plays a crucial role in guiding axons and regulating…”
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Neuropilin 1 and CD25 co-regulation during early murine thymic differentiation by Corbel, Catherine, Lemarchandel, Valérie, Thomas-Vaslin, Veronique, Pelus, Anne-Sophie, Agboton, Colette, Roméo, Paul-Henri

“…Neuropilin 1 (NP1) is a receptor for both semaphorin and vascular endothelial growth factor expressed by subpopulations of neuronal and endothelial cells. In…”
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MLL-ENL leukemia burden initiated in femoral diaphysis and preceded by mature B-cell depletion by Jaracz-Ros, A., Lewandowski, D., Barroca, V., Lavau, C., Romeo, P.-H.

“…Molecular and cellular events that resulted in leukemia development are well characterized but initial engraftment and proliferation of leukemic cells in bone…”
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SCL/TAL1 expression level regulates human hematopoietic stem cell self-renewal and engraftment by Reynaud, Damien, Ravet, Emmanuel, Titeux, Monique, Mazurier, Frédéric, Rénia, Laurent, Dubart-Kupperschmitt, Anne, Roméo, Paul-Henri, Pflumio, Françoise

“…The fate of hematopoietic stem cells (HSCs) is regulated through a combinatorial action of proteins that determine their self-renewal and/or their commitment…”
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Ultra-high-dose-rate FLASH and Conventional-Dose-Rate Irradiation Differentially Affect Human Acute Lymphoblastic Leukemia and Normal Hematopoiesis by Chabi, Sara, To, Thi Hong Van, Leavitt, Ron, Poglio, Sandrine, Jorge, Patrik Gonçalves, Jaccard, Maud, Petersson, Kristoffer, Petit, Benoit, Roméo, Paul-Henri, Pflumio, Françoise, Vozenin, Marie-Catherine, Uzan, Benjamin

“…Ultra-high-dose-rate FLASH radiation therapy has been shown to minimize side effects of irradiation in various organs while keeping antitumor efficacy. This…”
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Characterization of DNA-binding-dependent and -independent functions of SCL/TAL1 during human erythropoiesis by Ravet, Emmanuel, Reynaud, Damien, Titeux, Monique, Izac, Brigitte, Fichelson, Serge, Roméo, Paul-Henri, Dubart-Kupperschmitt, Anne, Pflumio, Françoise

“…The transcription factor TAL1 has major functions during embryonic hematopoiesis and in adult erythropoiesis and megakaryocytopoiesis. These functions rely on…”
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NRF2 Activation Impairs Quiescence and Bone Marrow Reconstitution Capacity of Hematopoietic Stem Cells by Murakami, Shohei, Suzuki, Takuma, Harigae, Hideo, Romeo, Paul-Henri, Yamamoto, Masayuki, Motohashi, Hozumi

“…Tissue stem cells are maintained in quiescence under physiological conditions but proliferate and differentiate to replenish mature cells under stressed…”
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In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis by Matos-Rodrigues, Gabriel, Barroca, Vilma, Muhammad, Ali-Akbar, Dardillac, Elodie, Allouch, Awatef, Koundrioukoff, Stephane, Lewandowski, Daniel, Despras, Emmanuelle, Guirouilh-Barbat, Josée, Frappart, Lucien, Kannouche, Patricia, Dupaigne, Pauline, Le Cam, Eric, Perfettini, Jean-Luc, Romeo, Paul-Henri, Debatisse, Michelle, Jasin, Maria, Livera, Gabriel, Martini, Emmanuelle, Lopez, Bernard S

“…Homologous recombination (HR) is a prominent DNA repair pathway maintaining genome integrity. Mutations in many HR genes lead to cancer predisposition…”
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A genetic variant controls interferon-β gene expression in human myeloid cells by preventing C/EBP-β binding on a conserved enhancer by Assouvie, Anaïs, Rotival, Maxime, Hamroune, Juliette, Busso, Didier, Romeo, Paul-Henri, Quintana-Murci, Lluis, Rousselet, Germain

“…Interferon β (IFN-β) is a cytokine that induces a global antiviral proteome, and regulates the adaptive immune response to infections and tumors. Its effects…”
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Keap1‐Nrf2 system regulates cell fate determination of hematopoietic stem cells by Murakami, Shohei, Shimizu, Ritsuko, Romeo, Paul‐Henri, Yamamoto, Masayuki, Motohashi, Hozumi

“…Nrf2 is a major transcriptional activator of cytoprotective genes against oxidative/electrophilic stress, and Keap1 negatively regulates Nrf2. Emerging works…”
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The MAL Gene Is Expressed in Primary Mediastinal Large B-Cell Lymphoma by Copie-Bergman, Christiane, Gaulard, Philippe, Maouche-Chrétien, Leı¨la, Brière, Josette, Haioun, Corinne, Alonso, Miguel A., Roméo, Paul-Henri, Leroy, Karen

“…Primary mediastinal large B-cell lymphoma (PMBL) appears to be a distinct clinicopathologic entity among diffuse large B-cell lymphomas (DLBLs). To find…”
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Tumor resistance to radiotherapy is triggered by an ATM/TAK1-dependent-increased expression of the cellular prion protein by Bernardino-Sgherri, Jacqueline, Siberchicot, Capucine, Auvré, Frédéric, Busso, Didier, Brocas, Clémentine, El Masri, Ghazi, Lioutsko, Anna, Ferri, Federica, Radicella, J. Pablo, Romeo, Paul-Henri, Bravard, Anne

“…In solid cancers, high expression of the cellular prion protein (PrPC) is associated with stemness, invasiveness, and resistance to chemotherapy, but the role…”
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Molecular identity of hematopoietic precursor cells emerging in the human embryo by LABASTIE, M.-C, CORTES, F, ROMEO, P.-H, DULAC, C, PEAULT, B

“…It is now accepted from studies in animal models that hematopoietic stem cells emerge in the para-aortic mesoderm-derived aorta-gonad-mesonephros region of the…”
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Low-Dose Irradiation Promotes Persistent Oxidative Stress and Decreases Self-Renewal in Hematopoietic Stem Cells by Rodrigues-Moreira, Sarah, Moreno, Stéphanie G., Ghinatti, Giulia, Lewandowski, Daniel, Hoffschir, Françoise, Ferri, Federica, Gallouet, Anne-Sophie, Gay, Denise, Motohashi, Hozumi, Yamamoto, Masayuki, Joiner, Michael C., Gault, Nathalie, Romeo, Paul-Henri

“…Despite numerous observations linking protracted exposure to low-dose (LD) radiation and leukemia occurrence, the effects of LD irradiation on hematopoietic…”
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