Search Results - "Román, Ángel‐Carlos"

ZFP207 sustains pluripotency by coordinating OCT4 stability, alternative splicing and RNA export by Malla, Sandhya, Prasad Bhattarai, Devi, Groza, Paula, Melguizo‐Sanchis, Dario, Atanasoai, Ionut, Martinez‐Gamero, Carlos, Román, Ángel‐Carlos, Zhu, Dandan, Lee, Dung‐Fang, Kutter, Claudia, Aguilo, Francesca

“…The pluripotent state is not solely governed by the action of the core transcription factors OCT4, SOX2, and NANOG, but also by a series of co‐transcriptional…”
Get full text

Immunomodulatory effects of inactivated Ligilactobacillus salivarius CECT 9609 on respiratory epithelial cells by Bravo, María, Diaz-Chamorro, Selene, Garrido-Jiménez, Sergio, Blanco, Javier, Simón, Irene, García, Waldo, Montero, María José, Gonçalves, Pilar, Martínez, Carlos, Cumplido-Laso, Guadalupe, Benítez, Dixan Agustín, Mulero-Navarro, Sonia, Centeno, Francisco, Román, Ángel Carlos, Fernández-Llario, Pedro, Cerrato, Rosario, Carvajal-González, José María

“…Abstract The microbiota in humans and animals play crucial roles in defense against pathogens and offer a promising natural source for immunomodulatory…”
Get full text

In Silico Research of New Therapeutics Rotenoids Derivatives against Leishmania amazonensis Infection by Vicente-Barrueco, Adrián, Román, Ángel Carlos, Ruiz-Téllez, Trinidad, Centeno, Francisco

“…Yearly, 1,500,000 cases of leishmaniasis are diagnosed, causing thousands of deaths. To advance in its therapy, we present an interdisciplinary protocol that…”
Get full text

Next generation sequencing technologies to address aberrant mRNA translation in cancer by Román, Ángel-Carlos, Benítez, Dixan A, Díaz-Pizarro, Alba, Del Valle-Del Pino, Nuria, Olivera-Gómez, Marcos, Cumplido-Laso, Guadalupe, Carvajal-González, Jose M, Mulero-Navarro, Sonia

“…In this review, we explore the transformative impact of next generation sequencing technologies in the realm of translatomics (the study of how translational…”
Get full text

METTL3 regulates breast cancer-associated alternative splicing switches by Achour, Cyrinne, Bhattarai, Devi Prasad, Groza, Paula, Román, Ángel-Carlos, Aguilo, Francesca

“…Alternative splicing (AS) enables differential inclusion of exons from a given transcript, thereby contributing to the transcriptome and proteome diversity…”
Get full text

Title: p38δ Regulates IL6 Expression Modulating ERK Phosphorylation in Preadipocytes by Díaz-Chamorro, Selene, Garrido-Jiménez, Sergio, Barrera-López, Juan Francisco, Mateos-Quirós, Clara María, Cumplido-Laso, Guadalupe, Lorenzo, María Jesús, Román, Ángel Carlos, Bernardo, Edgar, Sabio, Guadalupe, Carvajal-González, José María, Centeno, Francisco

“…IL6 is an essential cytokine in metabolism regulation and for intercommunication among different organs and tissues. IL6 produced by different tissues has…”
Get full text

Aryl hydrocarbon receptor controls skin homeostasis, regeneration, and hair follicle cycling by adjusting epidermal stem cell function by Rico‐Leo, Eva María, Lorenzo‐Martín, Luis Francisco, Román, Ángel Carlos, Bustelo, Xosé Ramón, Merino, Jaime María, Fernández‐Salguero, Pedro María

“…Skin integrity requires constant maintenance of a quiescent, yet responsive, population of stem cells. While interfollicular epidermal progenitors control…”
Get full text

Distribution of planar cell polarity proteins in the developing avian retina by Álvarez-Hernán, Guadalupe, Garrido-Jiménez, Sergio, Román, Ángel Carlos, Carvajal-González, José María, Francisco-Morcillo, Javier

“…Planar cell polarity (PCP) is evolutionary conserved and play a critical role in proper tissue development and function. During central nervous system…”
Get full text

Metabarcoding analysis reveals a differential bacterial community profile associated with ‘Torta del Casar’ and ‘Queso de la Serena’ PDO cheeses by Merchán, Almudena V., Ruiz-Moyano, Santiago, Benito, María José, Vázquez Hernández, María, Cabañas, Catalina M., Román, Ángel Carlos

“…A detailed understanding of the microbial ecology of artisanal cheeses is a crucial factor for implementation practices that can help to update their quality…”
Get full text

RNA-Seq Analysis to Measure the Expression of SINE Retroelements by Román, Ángel Carlos, Morales-Hernández, Antonio, Fernández-Salguero, Pedro M

“…The intrinsic features of retroelements, like their repetitive nature and disseminated presence in their host genomes, demand the use of advanced methodologies…”
Get more information

Wg and Wnt4 provide long-range directional input to planar cell polarity orientation in Drosophila by Wu, Jun, Roman, Angel-Carlos, Carvajal-Gonzalez, Jose Maria, Mlodzik, Marek

“…Planar cell polarity (PCP) is cellular polarity within the plane of an epithelial tissue or organ. PCP is established through interactions of the core Frizzled…”
Get full text

Rosmarinus officinalis reduces the ochratoxin A production by Aspergillus westerdijkiae in a dry-cured fermented sausage-based medium by Álvarez, Micaela, Andrade, María J., Delgado, Josué, Núñez, Félix, Román, Ángel-Carlos, Rodrigues, Paula

“…Aspergillus westerdijkiae is an ochratoxin A (OTA) producer mould in dry-cured meat products. To prevent the presence of ochratoxigenic moulds in dry-cured…”
Get full text

Positioning of centrioles is a conserved readout of Frizzled planar cell polarity signalling by Carvajal-Gonzalez, Jose Maria, Roman, Angel-Carlos, Mlodzik, Marek

“…Planar cell polarity (PCP) signalling is a well-conserved developmental pathway regulating cellular orientation during development. An evolutionarily conserved…”
Get full text

Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch by López-Arribillaga, Erika, Rodilla, Verónica, Pellegrinet, Luca, Guiu, Jordi, Iglesias, Mar, Roman, Angel Carlos, Gutarra, Susana, González, Susana, Muñoz-Cánoves, Pura, Fernández-Salguero, Pedro, Radtke, Freddy, Bigas, Anna, Espinosa, Lluís

“…Genetic data indicate that abrogation of Notch-Rbpj or Wnt-β-catenin pathways results in the loss of the intestinal stem cells (ISCs). However, whether the…”
Get full text

Histone H4 acetylation regulates behavioral inter-individual variability in zebrafish by Román, Angel-Carlos, Vicente-Page, Julián, Pérez-Escudero, Alfonso, Carvajal-González, Jose M, Fernández-Salguero, Pedro M, de Polavieja, Gonzalo G

“…Animals can show very different behaviors even in isogenic populations, but the underlying mechanisms to generate this variability remain elusive. We use the…”
Get full text

Variations in Fruit Ploidy Level and Cell Size between Small- and Large-Fruited Olive Cultivars during Fruit Ontogeny by Camarero, Maria C, Briegas, Beatriz, Corbacho, Jorge, Labrador, Juana, Román, Ángel-Carlos, Verde, Antía, Gallardo, Mercedes, Gomez-Jimenez, Maria C

“…Olive ( L.) is one of the major oil fruit tree crops worldwide. However, the mechanisms underlying olive fruit growth remain poorly understood. Here, we…”
Get full text

Dioxin receptor and SLUG transcription factors regulate the insulator activity of B1 SINE retrotransposons via an RNA polymerase switch by Román, Angel Carlos, González-Rico, Francisco J, Moltó, Eduardo, Hernando, Henar, Neto, Ana, Vicente-Garcia, Cristina, Ballestar, Esteban, Gómez-Skarmeta, José L, Vavrova-Anderson, Jana, White, Robert J, Montoliu, Lluís, Fernández-Salguero, Pedro M

“…Complex genomes utilize insulators and boundary elements to help define spatial and temporal gene expression patterns. We report that a genome-wide B1 SINE…”
Get full text

The clathrin adaptor AP-1 complex and Arf1 regulate planar cell polarity in vivo by Carvajal-Gonzalez, Jose Maria, Balmer, Sophie, Mendoza, Meg, Dussert, Aurore, Collu, Giovanna, Roman, Angel-Carlos, Weber, Ursula, Ciruna, Brian, Mlodzik, Marek

“…A key step in generating planar cell polarity (PCP) is the formation of restricted junctional domains containing Frizzled/Dishevelled/Diego (Fz/Dsh/Dgo) or Van…”
Get full text

Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor by González-Rico, Francisco J, Vicente-García, Cristina, Fernández, Almudena, Muñoz-Santos, Diego, Montoliu, Lluís, Morales-Hernández, Antonio, Merino, Jaime M, Román, Angel-Carlos, Fernández-Salguero, Pedro M

“…Transcriptional repression of Nanog is an important hallmark of stem cell differentiation. Chromatin modifications have been linked to the epigenetic profile…”
Get full text

Diminished Expression of Fat and Dachsous PCP Proteins Impaired Centriole Planar Polarization in Drosophila by Garrido-Jimenez, Sergio, Roman, Angel-Carlos, Carvajal-Gonzalez, Jose Maria

“…Proper ciliary basal body positioning within a cell is key for cilia functioning. Centriole and basal body positioning depends on signaling pathways such as…”
Get full text