Search Results - "Rols, M.P"
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Mechanisms of cell membrane electropermeabilization: A minireview of our present (lack of ?) knowledge
Published in Biochimica et biophysica acta (05-08-2005)“…Cell electropulsation is routinely used in cell Biology for protein, RNA or DNA transfer. Its clinical applications are under development for targeted drug…”
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Imaging living cells surface and quantifying its properties at high resolution using AFM in QI™ mode
Published in Micron (Oxford, England : 1993) (01-05-2013)“…► This paper presents results obtained using the AFM quantitative imaging mode. ► We explored the surface topography, nanomechanical or adhesion properties of…”
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Drug delivery by electropulsation: Recent developments in oncology
Published in International journal of pharmaceutics (14-02-2012)“…Electro-permeabilisation allows the free access of polar compounds to the cytoplasm by a reversible alteration of the cell membrane. It is now used in clinics…”
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In Vitro Gene Transfer by Electrosonoporation
Published in Ultrasound in medicine & biology (01-10-2010)“…Abstract Among the nonviral methods for gene delivery in vitro , electroporation is simple, inexpensive and safe. To upregulate the expression level of…”
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Polymeric self-assemblies for photodynamic therapy: A critical approach
Published in Photodiagnosis and photodynamic therapy (01-03-2017)“…The work presented here suggests a new approach in the critical development of polymeric nanovectors for photodynamic therapy (PDT) against cancer. Whereas…”
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Pre-treatment of cells with pluronic L64 increases DNA transfection mediated by electrotransfer
Published in Journal of controlled release (20-01-2011)“…Gene transfer into muscle cells is a key issue in biomedical research. Indeed, it is important for the development of new therapy for many genetic disorders…”
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An experimental evaluation of the critical potential difference inducing cell membrane electropermeabilization
Published in Biophysical journal (01-07-1993)“…When applied on intact cell suspension, electric field pulses are known to induce membrane permeabilization (electropermeabilization) and fusion…”
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Electropermeabilization of mammalian cells. Quantitative analysis of the phenomenon
Published in Biophysical journal (01-11-1990)“…Transient membrane permeabilization by application of high electric field intensity pulses on cells (electropermeabilization) depends on several physical…”
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Electrochemotherapy of horses. A preliminary clinical report
Published in Bioelectrochemistry (Amsterdam, Netherlands) (2002)“…Sarcoids are skin spontaneous tumours detected in horses. It can be cured by chemotherapy by using cisplatin. A multisequence treatment must be performed…”
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Interactions of amphiphilic polyoxazolines formulated or not in lipid nanocapsules with biological systems: Evaluation from membrane models up to in vivo mice epidermis
Published in European journal of pharmaceutics and biopharmaceutics (01-11-2022)“…[Display omitted] •Amphiphilic polyoxazolines interact with membrane models, from simple lipid bilayer until their in vivo skin penetration.•Saturated lipid…”
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Direct visualization at the single-cell level of siRNA electrotransfer into cancer cells
Published in Proceedings of the National Academy of Sciences - PNAS (28-06-2011)“…The RNA interference-mediated gene silencing approach is promising for therapies based on the targeted inhibition of disease-relevant genes…”
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Gene electrotransfer: comparison between 2D cultured cells and multicellular tumor spheroid model
Published in Drug discovery today (01-12-2010)Get full text
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Electrochemotherapy guided by intraoperative fluorescence imaging for the treatment of inoperable peritoneal micro-metastases
Published in Journal of controlled release (10-07-2016)“…Surgery is often the first therapeutic indication in cancer. Patient survival essentially depends on the completeness of tumor resection. This is a major…”
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Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery
Published in Gene therapy (01-02-2005)“…Owing to their capacity to induce strong, sequence-specific, gene silencing in cells, short interfering RNAs (siRNAs) represent new potential therapeutic…”
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In vitro and in vivo electric field-mediated permeabilization, gene transfer, and expression
Published in Methods (San Diego, Calif.) (01-06-2004)“…Electropulsation is one of the non-viral methods successfully used to transfer genes into living cells in vitro as in vivo. This approach shows promise in the…”
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Electropermeabilization of cell membranes
Published in Advanced drug delivery reviews (04-01-1999)“…A position dependent modulation of the membrane potential difference is induced when an electric field is applied to a cell. When cells are submitted to short…”
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Post-pulse addition of trans-cyclohexane-1,2-diol improves electrotransfer mediated gene expression in mammalian cells
Published in Biochemistry and biophysics reports (01-09-2016)“…Electric field mediated gene transfer is facing a problem in expression yield due to the poor transfer across the nuclear envelope. Trans-cyclohexane-1,2-diol…”
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New insights in the visualization of membrane permeabilization and DNA/membrane interaction of cells submitted to electric pulses
Published in Biochimica et biophysica acta (05-08-2005)“…Electropermeabilization designates the use of electric pulses to overcome the barrier of the cell membrane. This physical method is used to transfer anticancer…”
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R96: Étude de l’électrotransfection sur modèle sphéroïde
Published in Bulletin du cancer (01-10-2010)Get full text
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Control by pulse parameters of electric field-mediated gene transfer in mammalian cells
Published in Biophysical journal (01-02-1994)“…Electric field-mediated gene transfer in mammalian cells (electrotransformation) depends on the pulsing conditions (field intensity, pulse duration, number of…”
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