Search Results - "Rolnitzky, Linda M."

Kinetin in Familial Dysautonomia Carriers: Implications for a New Therapeutic Strategy Targeting mRNA Splicing by Gold-von Simson, Gabrielle, Goldberg, Judith D, Rolnitzky, Linda M, Mull, James, Leyne, Maire, Voustianiouk, Andrei, Slaugenhaupt, Susan A, Axelrod, Felicia B

“…Familial dysautonomia (FD) is caused by an intronic splice mutation in the IκB kinase–associated protein gene ( IKBKAP ) that leads to partial skipping of exon…”
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Power law behavior of RR-interval variability in healthy middle-aged persons, patients with recent acute myocardial infarction, and patients with heart transplants by Bigger, J. T. Jr, Steinman, R. C., Rolnitzky, L. M., Fleiss, J. L., Albrecht, P., Cohen, R. J.

“…BACKGROUND. The purposes of the present study were (1) to establish normal values for the regression of log(power) on log(frequency) for, RR-interval…”
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RR variability in healthy, middle-aged persons compared with patients with chronic coronary heart disease or recent acute myocardial infarction by BIGGER, J. T, FLEISS, J. L, STEINMAN, R. C, ROLNITZKY, L. M, SCHNEIDER, W. J, STEIN, P. K

“…The purpose of this investigation was to establish normal values of RR variability for middle-aged persons and compare them with values found in patients early…”
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IKBKAP mRNA in Peripheral Blood Leukocytes: A Molecular Marker of Gene Expression and Splicing in Familial Dysautonomia by Gold-von Simson, Gabrielle, Leyne, Maire, Mull, James, Rolnitzky, Linda M, Goldberg, Judith D, Berlin, Dena, Axelrod, Felicia B, Slaugenhaupt, Susan A

“…The common familial dysautonomia (FD) mutation results in tissue specific mis-splicing with reduced amount of wild-type (WT) IκB kinase associated protein gene…”
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Frequency domain measures of heart period variability to assess risk late after myocardial infarction by Bigger, J.Thomas, Fleiss, Joseph L., Rolnitzky, Linda M., Steinman, Richard C.

“…Objectives. To determine whether spectral measures of heart period (RR) variability predict death when measured late after infarction, we studied patients in…”
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Correlations among time and frequency domain measures of heart period variability two weeks after acute myocardial infarction by Bigger, J.Thomas, Fleiss, Joseph L., Steinman, Richard C., Rolnitzky, Linda M., Kleiger, Robert E., Rottman, Jeffrey N.

“…Seven hundred fifteen participants from a multicenter natural history study of acute myocardial infarction were studied (1) to determine the correlations among…”
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Time course of recovery of heart period variability after myocardial infarction by Bigger, J.Thomas, Fleiss, Joseph L., Rolnitzky, Linda M., Steinman, Richard C., Schneider, William J.

“…Four components of the heart period power spectrum—ultra low frequency (<0.0033 Hz), very low frequency (0.0033 to <0.04 Hz), low frequency (0.04 to <0.15 Hz)…”
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Effect of atenolol and diltiazem on heart period variability in normal persons by Cook, James R., Thomas Bigger, J., Kleiger, Robert E., Fleiss, Joseph L., Steinman, Richard C., Rolnitzky, Linda M.

“…Several time and frequency domain measures of heart period variability are reduced 1 to 2 weeks after myocardial infarction, and a reduced standard deviation…”
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Components of heart rate variability measured during healing of acute myocardial infarction by Bigger, J.Thomas, Kleiger, Robert E., Fleiss, Joseph L., Rolnitzky, Linda M., Steinman, Richard C., Miller, J.Philip

“…A high degree of heart rate (HR) variability is found in persons with normal hearts, whereas low HR variability can be found in patients with severe coronary…”
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Efficient estimation of the heart period power spectrum suitable for physiologic or pharmacologic studies by Rottman, Jeffrey N., Steinman, Richard C., Albrecht, Paul, Bigger, J.Thomas, Rolnitzky, Linda M., Fleiss, Joseph L.

“…The standard deviation of the normal RR intervals (SDNN) computed over 24 hours predicts mortality after myocardial infarction. 1 The power spectrum of heart…”
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Comparison of baroreflex sensitivity and heart period variability after myocardial infarction by Bigger, J.Thomas, La Rovere, Maria Teresa, Steinman, Richard C., Fleiss, Joseph L., Rottman, Jeffrey N., Rolnitzky, Linda M., Schwartz, Peter J.

“…In animals, baroreflex sensitivity is inversely related to the likelihood of ventricular fibrillation during myocardial ischemia. After myocardial infarction…”
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Comparison of time- and frequency domain-based measures of cardiac parasympathetic activity in Holter recordings after myocardial infarction by Bigger, J.Thomas, Albrecht, Paul, Steinman, Richard C., Rolnitzky, Linda M., Fleiss, Joseph L., Cohen, Richard J.

“…The standard deviation of normal RR intervals predicts mortality after acute myocardial infarction independently of left ventricular function and ventricular…”
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Effects of digoxin and enalapril on heart period variability and response to head-up tilt in normal subjects by Kaufman, Elizabeth S., Bosner, Matthew S., Bigger, J.Thomas, Stein, Phyllis K., Kleiger, Robert E., Rolnitzky, Linda M., Steinman, Richard C., Fleiss, Joseph L.

“…To test the effects of digitalis and angiotensinconverting enzyme inhibition on the RR interval variability in an electrocardiogram, 20 normal subjects were…”
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Predicting mortality after myocardial infarction from the response of RR variability to antiarrhythmic drug therapy by Bigger, J.Thomas, Rolnitzky, Linda M., Steinman, Richard C., Fleiss, Joseph L.

“…Objectives. This study was designed to test the hypothesis that antiarrhythmic drugs that decrease RR variability will predict all-cause mortality during…”
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Prevalence, characteristics and significance of ventricular tachycardia detected by 24-hour continuous electrocardiographic recordings in the late hospital phase of acute myocardial infarction by Bigger, J.Thomas, Fleiss, Joseph L., Rolnitzky, Linda M.

“…A 24-hour continuous electrocardiographic recording was made 11 ± 3 days after acute myocardial infarction (AMI) in 820 of the 867 participants in the…”
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Vagal modulation of RR intervals during head-up tilt and the infusion of isoproterenol by Bloomfield, Daniel M., Bigger, J. Thomas, Pavri, Behzad B., Han, Jennifer, Fleiss, Joseph L., Rolnitzky, Linda M., Steinman, Richard C.

“…The objective of this study was to characterize the autonomic effects of 2 interventions, head-up tilt and isoproterenol infusion, which alter autonomic…”
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Smoking cessation in adolescents: the role of nicotine dependence, stress, and coping methods by Siqueira, L M, Rolnitzky, L M, Rickert, V I

“…To compare perceived reasons for continued smoking and withdrawal symptoms between current smokers and quitters in an inner-city adolescent population. To…”
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The ability of several short-term measures of RR variability to predict mortality after myocardial infarction by BIGGER, J. T, FLEISS, J. L, ROLNITZKY, L. M, STEINMAN, R. C

“…We studied 715 patients 2 weeks after myocardial infarction to test the hypothesis that short-term power spectral measures of RR variability (calculated from 2…”
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Frequency domain measures of heart period variability and mortality after myocardial infarction by THOMAS BIGGER, J. JR, FLEISS, J. L, STEINMAN, R. C, ROLNITZKY, L. M, KLEIGER, R. E, ROTTMAN, J. N

“…We studied 715 patients 2 weeks after myocardial infarction to establish the associations between six frequency domain measures of heart period variability…”
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Diagnostic Accuracy of Cardiac Magnetic Resonance Imaging in the Evaluation of Newly Diagnosed Heart Failure With Reduced Left Ventricular Ejection Fraction by Won, Eugene, MD, Donnino, Robert, MD, Srichai, Monvadi B., MD, Sedlis, Steven P., MD, Feit, Frederick, MD, Rolnitzky, Linda, MS, Miller, Louis H., MD, Iqbal, Sohah N., MD, Axel, Leon, MD, PhD, Nguyen, Brian, BS, Slater, James, MD, Shah, Binita, MD, MS

“…The aim of this study was to determine the diagnostic value of cardiac magnetic resonance (CMR) imaging with late gadolinium enhancement (LGE), cine imaging,…”
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