Search Results - "Rolli‐Derkinderen, M."

Distinct expression of interleukin (IL)‐36α, β and γ, their antagonist IL‐36Ra and IL‐38 in psoriasis, rheumatoid arthritis and Crohn's disease by Boutet, M.‐A., Bart, G., Penhoat, M., Amiaud, J., Brulin, B., Charrier, C., Morel, F., Lecron, J.‐C., Rolli‐Derkinderen, M., Bourreille, A., Vigne, S., Gabay, C., Palmer, G., Le Goff, B., Blanchard, F.

“…Summary Interleukin (IL)‐36α, IL‐36β and IL‐36γ are expressed highly in skin and are involved in the pathogenesis of psoriasis, while the antagonists IL‐36Ra…”
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Protective role of the antidiabetic drug metformin against chronic experimental pulmonary hypertension by Agard, C, Rolli‐Derkinderen, M, Dumas‐de‐La‐Roque, E, Rio, M, Sagan, C, Savineau, JP, Loirand, G, Pacaud, P

“…Background and purpose:  Pulmonary arterial hypertension (PAH) is associated with increased contraction and proliferation of pulmonary vascular smooth muscle…”
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Glioplasticity in irritable bowel syndrome by Lilli, N. L., Quénéhervé, L., Haddara, S., Brochard, C., Aubert, P., Rolli‐Derkinderen, M., Durand, T., Naveilhan, P., Hardouin, J.‐B., De Giorgio, R., Barbara, G., Bruley des Varannes, S., Coron, E., Neunlist, M.

“…Background Growing evidence indicates a wide array of cellular remodeling in the mucosal microenvironment during irritable bowel syndrome (IBS), which possibly…”
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n–3 polyunsaturated fatty acids in the maternal diet modify the postnatal development of nervous regulation of intestinal permeability in piglets by De Quelen, F., Chevalier, J., Rolli‐Derkinderen, M., Mourot, J., Neunlist, M., Boudry, G.

“…Non‐technical summary  In this study, we demonstrated that supplementation of the maternal diet with a particular fatty acid, 18:3 n‐3, the precursor of the…”
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Characterization of human, mouse, and rat cultures of enteric glial cells and their effect on intestinal epithelial cells by Soret, R., Coquenlorge, S., Cossais, F., Meurette, G., Rolli‐Derkinderen, M., Neunlist, M.

“…Background Enteric glial cells (EGC) are major regulators of neuronal and intestinal epithelial cell (IEC) functions. Simple isolation methods of EGC,…”
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Modulation of VIPergic phenotype of enteric neurons by colonic biopsy supernatants from patients with inflammatory bowel diseases: Involvement of IL‐6 in Crohn's disease by Soufflet, F., Biraud, M., Rolli‐Derkinderen, M., Lardeux, B., Trang, C., Coron, E., Bruley des Varannes, S., Bourreille, A., Neunlist, M.

“…Background Neuroplastic changes in the enteric nervous system (ENS) observed during IBD might participate in physiopathological processes. Vasoactive…”
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Phosphate Stimulates Matrix Gla Protein Expression in Chondrocytes through the Extracellular Signal Regulated Kinase Signaling Pathway by Julien, M, Magne, D, Masson, M, Rolli-Derkinderen, M, Chassande, O, Cario-Toumaniantz, C, Cherel, Y, Weiss, P, Guicheux, J

“…Whereas increasing evidence suggests that inorganic phosphate (Pi) may act as a signaling molecule in mineralization-competent cells, its mechanisms of action…”
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RhoA Expression Is Controlled by Nitric Oxide through cGMP-dependent Protein Kinase Activation by Sauzeau, V, Rolli-Derkinderen, M, Marionneau, C, Loirand, G, Pacaud, P

“…The small G protein RhoA is a convergence point for multiple signals that regulate smooth muscle cell functions. NO plays a major role in the structure and…”
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CA-184: Maintien de la barrière intestinale : quelle contribution pour la protéine kinase activée par l'AMP (AMPK) ? by Pochard, C, Cohen, D, Neunlist, M, Leclerc, J, Foretz, M, Rolli-Derkinderen, M, Viollet, B

“…Introduction Le développement de nouvelles stratégies thérapeutiques pour prévenir et traiter l'obésité se situe au cœur d'une problématique de santé publique,…”
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p38/SAPK2-dependent gene expression in Jurkat T cells by Rolli-Derkinderen, M, Gaestel, M

“…The stress-activated protein kinase p38/SAPK2 is known to regulate the activity of transcription factors and to control expression of several genes at the…”
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D021 Sildenafil induced-revascularization of rat hindlimb involved arteriogenesis through PI3K/-Akt and eNOS activation by Menguy, C, Bocquet, A, Guihot, A.-L, Toutain, B, Rolli-derkinderen, M, Chappard, D, Pacaud, P, Loirand, G, Henrion, D, Loufrani, L

“…Hypoxia and inflammation play a major role in the revascularization following ischemia. Sildenafil inhibits phosphodiesterase-5, increases intracellular cGMP…”
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Endogenous Regulation of Visceral Pain via Production of Opioids by Colitogenic CD4+ T Cells in Mice by Boué, Jérôme, Basso, Lilian, Cenac, Nicolas, Blanpied, Catherine, Rolli–Derkinderen, Malvyne, Neunlist, Michel, Vergnolle, Nathalie, Dietrich, Gilles

“…Background & Aims A dysregulated response of CD4+ T cells against the microbiota contributes to the development of inflammatory bowel disease. Effector CD4+ T…”
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Enteric glia protect against Shigella flexneri invasion in intestinal epithelial cells: a role for S-nitrosoglutathione by Flamant, Mathurin, Aubert, Philippe, Rolli-Derkinderen, Malvyne, Bourreille, Arnaud, Neunlist, Margarida Ribeiro, Mahé, Maxime M, Meurette, Guillaume, Marteyn, Benoit, Savidge, Tor, Galmiche, Jean Paul, Sansonetti, Philippe J, Neunlist, Michel

“…Enteric glial cells (EGCs) are important regulators of intestinal epithelial barrier (IEB) functions. EGC-derived S-nitrosoglutathione (GSNO) has been shown to…”
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Modulation of VIP ergic phenotype of enteric neurons by colonic biopsy supernatants from patients with inflammatory bowel diseases: Involvement of IL ‐6 in Crohn's disease by Soufflet, F., Biraud, M., Rolli‐Derkinderen, M., Lardeux, B., Trang, C., Coron, E., Bruley des Varannes, S., Bourreille, A., Neunlist, M.

“…Abstract Background Neuroplastic changes in the enteric nervous system ( ENS ) observed during IBD might participate in physiopathological processes…”
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Trends in histamine research: new functions during immune responses and hematopoiesis by Schneider, Elke, Rolli-Derkinderen, Malvyne, Arock, Michel, Dy, Michel

“…Histamine is a bioamine with multiple physiological activities. In the immune system, it not only mediates the deleterious effects accompanying allergic…”
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DOP23 Myenteric plexitis and post-operative recurrence in Crohn’s disease: the role of enteric glial cells and ICAM-1 by Le Berre, C, Pabois, J, Durand, T, Durieu, E, Rolli-Derkinderen, M, Bossard, C, Podevin, J, Neunlist, M, Neveu, I, Naveilhan, P, Bourreille, A

“…Abstract Background Half of Crohn’s disease (CD) patients require surgery within 20 years of diagnosis, and post-operative recurrence (POR) is frequent. Among…”
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Inhibition of RhoA/Rho kinase pathway is involved in the beneficial effect of sildenafil on pulmonary hypertension by Guilluy, Christophe, Sauzeau, Vincent, Rolli‐Derkinderen, Malvyne, Guérin, Patrice, Sagan, Christine, Pacaud, Pierre, Loirand, Gervaise

“…Inhibition of the type 5 phosphodiesterase and inhibition of Rho kinase are both effective in reducing pulmonary hypertension (PH). Here we investigate whether…”
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Phosphorylation of Serine 188 Protects RhoA from Ubiquitin/Proteasome-Mediated Degradation in Vascular Smooth Muscle Cells by Rolli-Derkinderen, Malvyne, Sauzeau, Vincent, Boyer, Laurent, Lemichez, Emmanuel, Baron, Céline, Henrion, Daniel, Loirand, Gervaise, Pacaud, Pierre

“…cAMP and cyclic GMP-dependent kinases (PKA and PKG) phosphorylate the small G protein RhoA on Ser188. We have previously demonstrated that phosphorylation of…”
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Distinct expression of interleukin (IL)-36[alpha], [beta] and [gamma], their antagonist IL-36Ra and IL-38 in psoriasis, rheumatoid arthritis and Crohn's disease by Boutet, M-A, Bart, G, Penhoat, M, Amiaud, J, Brulin, B, Charrier, C, Morel, F, Lecron, J-C, Rolli-Derkinderen, M, Bourreille, A, Vigne, S, Gabay, C, Palmer, G, Le Goff, B, Blanchard, F

“…Summary Interleukin (IL)-36[alpha], IL-36[beta] and IL-36[gamma] are expressed highly in skin and are involved in the pathogenesis of psoriasis, while the…”
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Sildenafil Prevents Change in RhoA Expression Induced by Chronic Hypoxia in Rat Pulmonary Artery by Sauzeau, Vincent, Rolli-Derkinderen, Malvyne, Lehoux, Stéphanie, Loirand, Gervaise, Pacaud, Pierre

“…ABSTRACT—Exposure to chronic hypoxia (CH) induces a sustained pulmonary hypertension associated with structural and functional changes in the pulmonary…”
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