Search Results - "Rollett, Alexandra"
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Myeloperoxidase-responsive materials for infection detection based on immobilized aminomethoxyphenol
Published in Biotechnology and bioengineering (01-12-2016)“…ABSTRACT There is a strong need for simple and fast diagnostic tools for the detection of wound infection. Immune system‐derived enzymes like myeloperoxidase…”
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2
Para-Derivatized Pybox Ligands As Sensitizers in Highly Luminescent Ln(III) Complexes
Published in Inorganic chemistry (04-10-2010)“…New complexes of pyridine-bis(oxazoline) derivatized with -H, -OMe, and -Br at the para position of the pyridine ring with Eu(III) and Tb(III) have been…”
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3
Silk-elastin-like protein biomaterials for the controlled delivery of therapeutics
Published in Expert opinion on drug delivery (01-05-2015)“…Genetically engineered biomaterials are useful for controlled delivery owing to their rational design, tunable structure-function, biocompatibility,…”
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4
Thiophene-Derivatized Pybox and Its Highly Luminescent Lanthanide Ion Complexes
Published in Journal of the American Chemical Society (19-12-2007)“…A new complex of 4-thiophen-3-yl-pyridine-2,6-bis(oxazoline) with Eu(III) triflate has been isolated. This complex and its Tb(III) analogue are luminescent in…”
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5
Chitosan based substrates for wound infection detection based on increased lysozyme activity
Published in Carbohydrate polymers (20-10-2016)“…•Visual detection of wound infection at an early stage.•A degree of N-acetylation of around 50% results best hydrolysis rates by lysozyme.•Dyes of varying…”
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Structural insights into pH-responsive drug release of self-assembling human serum albumin-silk fibroin nanocapsules
Published in European journal of pharmaceutics and biopharmaceutics (01-12-2018)“…[Display omitted] Inflammation processes are associated with significant decreases in tissue or lysosomal pH from 7.4 to 4, a fact that argues for the…”
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Folic acid-functionalized human serum albumin nanocapsules for targeted drug delivery to chronically activated macrophages
Published in International journal of pharmaceutics (10-05-2012)“…Activated synovial macrophages play a key role in Rheumatoid Arthritis (RA). Recent studies have shown that folate receptor beta (FRβ) is specifically…”
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8
Cellobiohydrolases Produce Different Oligosaccharides from Chitosan
Published in Biomacromolecules (13-06-2016)“…Chito-oligosaccharides (COSs) are bioactive molecules with interesting characteristics; however, their exploitation is still restricted due to limited amounts…”
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Antimicrobial Cellobiose Dehydrogenase-Chitosan Particles
Published in ACS applied materials & interfaces (13-01-2016)“…Increasing prevalence of chronic wounds and microbial infection constitute a severe health challenge. The situation is further complicated by emerging…”
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10
Internalization of Methotrexate Conjugates by Folate Receptor‑α
Published in Biochemistry (Easton) (11-12-2018)“…The folate antagonist methotrexate is a cytotoxic drug used in the treatment of several cancer types. The entry of methotrexate into the cell is mediated by…”
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HSA nanocapsules functionalized with monoclonal antibodies for targeted drug delivery
Published in International journal of pharmaceutics (15-12-2013)“…The chronic autoimmune disorder rheumatoid arthritis (RA) affects millions of adults and children every year. Chronically activated macrophages secreting…”
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Peptide Anchor for Folate-Targeted Liposomal Delivery
Published in Biomacromolecules (14-09-2015)“…Specific folate receptors are abundantly overexpressed in chronically activated macrophages and in most cancer cells. Directed folate receptor targeting using…”
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13
Size controlled protein nanoemulsions for active targeting of folate receptor positive cells
Published in Colloids and surfaces, B, Biointerfaces (01-11-2015)“…[Display omitted] •Stable BSA nanoemulsions are produced by high pressure homogenization.•Linear correlation is found between Poloxamer 407 levels and size of…”
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14
Enzyme responsive polymers
Published in New biotechnology (01-07-2014)Get full text
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Bioresponsive systems based on polygalacturonate containing hydrogels
Published in Enzyme and microbial technology (07-04-2011)“…Polysaccharide acid (PSA) based devices (consisting of alginic acid and polygalacturonic acid) were investigated for the detection of contaminating…”
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Covalent immobilisation of protease and laccase substrates onto siloxanes
Published in Chemosphere (Oxford) (01-08-2010)“…Immobilisation of enzyme substrates is a powerful tool in the detection of enzymes in the chemosphere and the environment. A siloxane based strategy for the…”
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