P07-06. HIV-1 transmission and early evolution: whole genome analysis

Given the rapid population growth that occurs in acute infection, and the subsequent decline in this population at the time of seroconversion, we tested for deviations from neutral evolution and found that the earliest time-points were more likely to deviate from apparent neutrality.

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Bibliographic Details
Published in:	Retrovirology Vol. 6; no. S3; p. P104
Main Authors:	Herbeck, JT, Rolland, MT, Deng, WC, Collier, AC, Mullins, JI
Format:	Journal Article
Language:	English
Published:	London BioMed Central 22-10-2009 BioMed Central Ltd BMC
Subjects:	Acquired immune deficiency syndrome AIDS Genomes HIV Human immunodeficiency virus Mutation Poster Presentation Vaccines
Online Access:	Get full text
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Description
Summary:	Given the rapid population growth that occurs in acute infection, and the subsequent decline in this population at the time of seroconversion, we tested for deviations from neutral evolution and found that the earliest time-points were more likely to deviate from apparent neutrality.
ISSN:	1742-4690 1742-4690
DOI:	10.1186/1742-4690-6-S3-P104