Search Results - "Rolland, Leah"

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  1. 1
    Uricase-Deficient Larval Zebrafish with Elevated Urate Levels Demonstrate Suppressed Acute Inflammatory Response to Monosodium Urate Crystals and Prolonged Crystal Persistence

    Uricase-Deficient Larval Zebrafish with Elevated Urate Levels Demonstrate Suppressed Acute Inflammatory Response to Monosodium Urate Crystals and Prolonged Crystal Persistence by Linnerz, Tanja, Sung, Yih Jian, Rolland, Leah, Astin, Jonathan W, Dalbeth, Nicola, Hall, Christopher J

    Published in Genes (22-11-2022)
    “…Gout is caused by elevated serum urate leading to the deposition of monosodium urate (MSU) crystals that can trigger episodes of acute inflammation. Humans are…”
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    Infection-experienced HSPCs protect against infections by generating neutrophils with enhanced mitochondrial bactericidal activity

    Infection-experienced HSPCs protect against infections by generating neutrophils with enhanced mitochondrial bactericidal activity by Darroch, Hannah, Keerthisinghe, Pramuk, Sung, Yih Jian, Rolland, Leah, Prankerd-Gough, Anneke, Crosier, Philip S., Astin, Jonathan W., Hall, Christopher J.

    Published in Science advances (08-09-2023)
    “…Hematopoietic stem and progenitor cells (HSPCs) respond to infection by proliferating and generating in-demand neutrophils through a process called emergency…”
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