Search Results - "Rolink, A. G."

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5 by Busslinger, Meinrad, Nutt, Stephen L, Heavey, Barry, Rolink, Antonius G

“…The Pax5 gene encoding the B-cell-specific activator protein (BSAP) is expressed within the haematopoietic system exclusively in the B-lymphoid lineage, where…”
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Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors by Rolink, Antonius G, Nutt, Stephen L, Melchers, Fritz, Busslinger, Meinrad

“…The mechanisms controlling the commitment of haematopoietic progenitors to the B-lymphoid lineage are poorly understood. The observations that mice deficient…”
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Selection events operating at various stages in B cell development by Rolink, Antonius G, Schaniel, Christoph, Andersson, Jan, Melchers, Fritz

“…B cells have to progress through various checkpoints during their process of development. The three transcription factors E2A, EBF (early B cell factor) and…”
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Roles of IGH and L Chains and of Surrogate H and L Chains in the Development of Cells of the B Lymphocyte Lineage by Melchers, F, Haasner, D, Grawunder, U, Kalberer, C, Karasuyama, H, Winkler, T, Rolink, A G

“…Proteins expressed from productively rearranged H and L chain gene loci have been implied in the regulation of Ig gene rearrangements during B lymphopoiesis…”
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Monoclonal antibodies reactive with the mouse interleukin 5 receptor by ROLINK, A. G, MELCHERS, F, PALACIOS, R

“…The rat mAbs R52.120 and R52.625 inhibit the action of IL-5 on both IL-5-sensitive cell lines and freshly isolated splenic B lymphocytes. Neither antibody…”
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Precursor B cells from Pax-5-deficient mice--stem cells for macrophages, granulocytes, osteoclasts, dendritic cells, natural killer cells, thymocytes and T cells by Rolink, A G, Melchers, F

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The cluster of ABCD chemokines which organizes T cell-dependent B cell responses by Schaniel, C, Melchers, F, Rolink, A G

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BAFF is a survival and maturation factor for mouse B cells by Rolink, Antonius G., Tschopp, Jürg, Schneider, Pascal, Melchers, Fritz

“…Human B cell‐activating factor (BAFF) induces mouse surface IgM+ B cells of the immature type from bone marrow and of the immature types 1 and 2 from spleen,…”
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The transition from immature to mature B cells by Rolink, A G, Melchers, F, Andersson, J

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Interleukin-3 and Interleukin-7 Are Alternative Growth Factors for the Same B-Cell Precursors in the Mouse by Winkler, Thomas H., Melchers, Fritz, Rolink, Antonius G.

“…Clones and lines of precursor (pre) B cells can be established by limiting dilutions of unseparated cell suspensions of fetal liver or bone marrow on stromal…”
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Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity by Rolink, Antonius G., Andersson, Jan, Melchers, Fritz

“…The transit of immature to mature sIgM+ B cells, the life span, maturation kinetics and response to polyclonal activators have been analyzed with the help of a…”
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Human macrophage-derived chemokine (MDC) is strongly expressed following activation of both normal and malignant precursor and mature B cells by Ghia, P, Schaniel, C, Rolink, A G, Nadler, L M, Cardoso, A A

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Attractions and migrations of lymphoid cells in the organization of humoral immune responses by Schaniel, C, Rolink, A G, Melchers, F

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Precursor B cell receptor-dependent B cell proliferation and differentiation does not require the bone marrow or fetal liver environment by Rolink, A G, Winkler, T, Melchers, F, Andersson, J

“…The capacity of precursor B (pre-B) I cells from fetal liver and bone marrow to proliferate and differentiate into surface immunoglobulin-positive immature B…”
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Targeted inactivation of mouse RAD52 reduces homologous recombination but not resistance to ionizing radiation by Rijkers, T, Van Den Ouweland, J, Morolli, B, Rolink, A G, Baarends, W M, Van Sloun, P P, Lohman, P H, Pastink, A

“…The RAD52 epistasis group is required for recombinational repair of double-strand breaks (DSBs) and shows strong evolutionary conservation. In Saccharomyces…”
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Repertoire selection by pre-B-cell receptors and B-cell receptors, and genetic control of B-cell development from immature to mature B cells by Melchers, F, ten Boekel, E, Seidl, T, Kong, X C, Yamagami, T, Onishi, K, Shimizu, T, Rolink, A G, Andersson, J

“…During B-cell development the surrogate light (SL) chain is selectively expressed in progenitor and precursor B cells during the developmental stages of D(H)…”
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The Role of Chemokines in Regulating Cell Migration during Humoral Immune Responses by Melchers, Fritz, Rolink, Antonius G, Schaniel, Christoph

“…Three major types of hematopoietic cells cooperate in the recognition of antigens in humoral adaptive immune responses: T lymphocytes, B lymphocytes, and…”
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A novel CC chemokine ABCD-1, produced by dendritic cells and activated B cells, exclusively attracts activated T lymphocytes by Schaniel, C, Sallusto, F, Sideras, P, Melchers, F, Rolink, A G

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The anti‐apoptotic factor Bcl‐2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF by Tardivel, Aubry, Tinel, Antoine, Lens, Susanne, Steiner, Quynh‐Giao, Sauberli, Estelle, Wilson, Anne, Mackay, Fabienne, Rolink, Antonius G., Beermann, Friedrich, Tschopp, Jürg, Schneider, Pascal

“…The TNF family ligand B cell‐activating factor (BAFF, BLyS, TALL‐1) is an essential factor for B cell development. BAFF binds to three receptors, BAFF‐R,…”
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The molecular basis of B-cell lineage commitment by Nutt, S L, Rolink, A G, Busslinger, M

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