Search Results - "Rolim, Hercília Maria Lins"
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Palmatine antioxidant and anti-acetylcholinesterase activities: A pre-clinical assessment
Published in Cellular and Molecular Biology (25-06-2020)“…There is evidence that palmatine (PA), an alkaloid isolated from the Guatteria friesiana plant, has some important biological activities, including…”
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Andrographolide, a diterpene lactone from Andrographis paniculata and its therapeutic promises in cancer
Published in Cancer letters (28-04-2018)“…The diterpene lactone andrographolide, isolated from Andrographis paniculata, has been proven to possess several important protective biological activities,…”
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3
Occupational and life-style factors-acquired mutagenicity in agric-workers of northeastern Brazil
Published in Environmental science and pollution research international (01-06-2017)“…Pesticides are a complex mixture of chemicals used to protect crops from a number of pests and diseases. They have been considered as potential mutagenic…”
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4
Mycotoxin‐assisted mitochondrial dysfunction and cytotoxicity: Unexploited tools against proliferative disorders
Published in IUBMB life (01-11-2018)“…Mitochondria are the powerhouse of cells, which upon dysfunctions may lead to several diseases. Mycotoxins are the toxic secondary metabolites from fungi which…”
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Diterpenes as lead molecules against neglected tropical diseases
Published in Phytotherapy research (01-02-2017)“…Nowadays, neglected tropical diseases (NTDs) are reported to be present everywhere. Poor and developing areas in the world have received great attention to…”
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6
Advances in Antitumor Effects Using Liposomal Citrinin in Induced Breast Cancer Model
Published in Pharmaceutics (26-01-2024)“…The study aimed to evaluate the antitumor and toxicogenetic effects of liposomal nanoformulations containing citrinin in animal breast carcinoma induced by…”
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ADMET study and inhibition of Staphylococcus aureus efflux pumps by a synthetic p-aminochalcone
Published in Results in Chemistry (01-01-2024)“…[Display omitted] Bacterial resistance is a global health problem that needs to be solved through discovery of new therapeutic strategies. This study aimed to…”
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A comprehensive review on biological properties of citrinin
Published in Food and chemical toxicology (01-12-2017)“…Citrinin (CIT) is a mycotoxin which causes contamination in the food and is associated with different toxic effects. A web search on CIT has been conducted…”
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Involvement of the serotoninergic system in the anxiolytic action mechanism of a liposomal formulation containing nimodipine (NMD-Lipo)
Published in Pharmacology, biochemistry and behavior (01-11-2023)“…In the search for anxiolytic drugs with fewer adverse effects, calcium blockers were proposed as a benzodiazepines (BZDs) alternative. In this context, the…”
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10
Antidepressant-like activity of liposomal formulation containing nimodipine treatment in the tail suspension test, forced swim test and MAOB activity in mice
Published in Brain research (01-09-2016)“…Abstract Previous studies have shown that intracellular calcium ion dysfunction may be an etiological factor in affective illness. Nimodipine (NMD) is a Ca2+…”
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Cytotoxicity of doxorubicin-loaded Con A-liposomes
Published in Drug development research (01-05-2006)“…The present study investigated the potential of Concanavalin A lectin (Con A) conjugated to liposomes (Con A‐liposomes) for targeting doxorubicin (DOX) to…”
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12
Gastroprotective effect of α-terpineol-loaded polymethyl methacrylate particles on gastric injury model
Published in Journal of drug delivery science and technology (01-01-2022)“…Terpenes present in essential oils have been promising for studies of gastroprotective activity. A monoterpene constituent of Melaleuca quinquenervia (Cav.)…”
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13
Acute toxicity and anticonvulsant activity of liposomes containing nimodipine on pilocarpine-induced seizures in mice
Published in Neuroscience letters (12-01-2015)“…[Display omitted] •NMD-Lipo did not produce acute toxicity in mice.•NMD-Lipo has anticonvulsant activity on pilocarpine-induced seizures in mice.•NMD-Lipo…”
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14
Cardioprotector Activity of an Esteroidal Saponin: A Scientific and Technological Prospection
Published in Recent patents on biotechnology (2017)“…Cardiovascular diseases are a group of disorders of the heart and blood vessels that account for a major cause of premature death worldwide. Diosgenin saponin…”
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15
Evaluation of toxic, cytotoxic and genotoxic effects of phytol and its nanoemulsion
Published in Chemosphere (Oxford) (01-06-2017)“…Phytol (PYT) is a diterpenoid having important biological activity. However, it is a water non-soluble compound. This study aims to prepare PYT nanoemulsion…”
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16
Development and evaluation of liposomal formulation containing nimodipine on anxiolytic activity in mice
Published in Pharmacology, biochemistry and behavior (01-01-2014)“…Nimodipine has been investigated in the treatment of anxiety. Its administration, however, presents a number of limitations, particularly by low…”
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Nanoencapsulação de um peptídeo isolado de anuros: citotoxicidade in vitro em células tumorais humanas
Published in Revista de ciências farmacêuticas básica e aplicada (01-01-2014)“…A terapia antineoplásica tradicional apresenta algumas limitações que podem ser superadas através da utilização dos lipossomas. Estes nanossistemas de…”
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Diterpenes as lead molecules against neglected tropical diseases: Diterpenes Acting Against Neglected Tropical Diseases
Published in Phytotherapy research (01-02-2017)Get full text
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Nanoencapsulação de um peptídeo isolado de anuros: citotoxicidade in vitro em células tumorais humanas
Published in Revista de ciências farmacêuticas básica e aplicada (01-01-2014)“…A terapia antineoplásica tradicional apresenta algumas limitações que podem ser superadas através da utilização dos lipossomas. Estes nanossistemas de…”
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Pharmacological properties of cashew (Anacardium occidentale)
Published in African journal of biotechnology (31-08-2016)Get full text
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