Search Results - "Rolfe, Matthew D"

Lag Phase Is a Distinct Growth Phase That Prepares Bacteria for Exponential Growth and Involves Transient Metal Accumulation by Rolfe, Matthew D, Rice, Christopher J, Lucchini, Sacha, Pin, Carmen, Thompson, Arthur, Cameron, Andrew D. S, Alston, Mark, Stringer, Michael F, Betts, Roy P, Baranyi, József, Peck, Michael W, Hinton, Jay C. D

“…Lag phase represents the earliest and most poorly understood stage of the bacterial growth cycle. We developed a reproducible experimental system and conducted…”
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Staphylococcus aureus adaptation to aerobic low-redox-potential environments: implications for an intracellular lifestyle by Christmas, Benjamin A F, Rolfe, Matthew D, Rose, Matthew, Green, Jeffrey

“…Methicillin-resistant Staphylococcus aureus is a 'superbug' that is responsible for extensive death and morbidity. Chronic S. aureus infections are associated…”
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Structure of a Wbl protein and implications for NO sensing by M. tuberculosis by Kudhair, Bassam K., Hounslow, Andrea M., Rolfe, Matthew D., Crack, Jason C., Hunt, Debbie M., Buxton, Roger S., Smith, Laura J., Le Brun, Nick E., Williamson, Michael P., Green, Jeffrey

“…Mycobacterium tuberculosis causes pulmonary tuberculosis (TB) and claims ~1.8 million human lives per annum. Host nitric oxide (NO) is important in controlling…”
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Identification of new members of the Escherichia coli K-12 MG1655 SlyA regulon by Curran, Thomas D, Abacha, Fatima, Hibberd, Stephen P, Rolfe, Matthew D, Lacey, Melissa M, Green, Jeffrey

“…SlyA is a member of the MarR family of bacterial transcriptional regulators. Previously, SlyA has been shown to directly regulate only two operons in…”
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Transcript Profiling and Inference of Escherichia coli K-12 ArcA Activity across the Range of Physiologically Relevant Oxygen Concentrations by Rolfe, Matthew D., Beek, Alex Ter, Graham, Alison I., Trotter, Eleanor W., Asif, H. M. Shahzad, Sanguinetti, Guido, de Mattos, Joost Teixeira, Poole, Robert K., Green, Jeffrey

“…Oxygen availability is the major determinant of the metabolic modes adopted by Escherichia coli. Although much is known about E. coli gene expression and…”
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Reprogramming of Escherichia coli K-12 metabolism during the initial phase of transition from an anaerobic to a micro-aerobic environment by Trotter, Eleanor W, Rolfe, Matthew D, Hounslow, Andrea M, Craven, C Jeremy, Williamson, Michael P, Sanguinetti, Guido, Poole, Robert K, Green, Jeffrey

“…Many bacteria undergo transitions between environments with differing O₂ availabilities as part of their natural lifestyles and during biotechnological…”
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Agent-based modeling of oxygen-responsive transcription factors in Escherichia coli by Bai, Hao, Rolfe, Matthew D, Jia, Wenjing, Coakley, Simon, Poole, Robert K, Green, Jeffrey, Holcombe, Mike

“…In the presence of oxygen (O2) the model bacterium Escherichia coli is able to conserve energy by aerobic respiration. Two major terminal oxidases are involved…”
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Transcriptional regulation of bacterial virulence gene expression by molecular oxygen and nitric oxide by Green, Jeffrey, Rolfe, Matthew D, Smith, Laura J

“…Molecular oxygen (O 2 ) and nitric oxide (NO) are diatomic gases that play major roles in infection. The host innate immune system generates reactive oxygen…”
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Characterization of Salmonella enterica serovar Typhimurium aconitase A by Baothman, Othman A S, Rolfe, Matthew D, Green, Jeffrey

“…Aconitases (Acn) are iron-sulfur proteins that catalyse the reversible isomerization of citrate and isocitrate via the intermediate cis-aconitate in the Krebs…”
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Homeostasis of metabolites in Escherichia coli on transition from anaerobic to aerobic conditions and the transient secretion of pyruvate by Yasid, Nur Adeela, Rolfe, Matthew D., Green, Jeffrey, Williamson, Mike P.

“…We have developed a method for rapid quenching of samples taken from chemostat cultures of Escherichia coli that gives reproducible and reliable measurements…”
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The Bacterial Signal Molecule, ppGpp, Mediates the Environmental Regulation of Both the Invasion and Intracellular Virulence Gene Programs of Salmonella by Thompson, Arthur, Rolfe, Matthew D., Lucchini, Sacha, Schwerk, Peter, Hinton, Jay C.D., Tedin, Karsten

“…During infection of mammalian hosts, facultative intracellular pathogens have to adjust rapidly to different environmental conditions encountered during…”
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Identification of a New Member of the Phage Shock Protein Response in Escherichia coli, the Phage Shock Protein G (PspG)[boxs] by Lloyd, Louise J., Jones, Susan E., Jovanovic, Goran, Gyaneshwar, Prasad, Rolfe, Matthew D., Thompson, Arthur, Hinton, Jay C., Buck, Martin

“…The phage shock protein operon (pspABCDE) of Escherichia coli is strongly up-regulated in response to overexpression of the filamentous phage secretin protein…”
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Release of nitric oxide by the Escherichia coli YtfE (RIC) protein and its reduction by the hybrid cluster protein in an integrated pathway to minimize cytoplasmic nitrosative stress by Balasiny, Basema, Rolfe, Matthew D, Vine, Claire, Bradley, Charlene, Green, Jeffrey, Cole, Jeff

“…Synthesis of the Escherichia coli YtfE protein, also known as RIC, for the repair of damaged iron centres, is highly induced during anaerobic growth under…”
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Systems analysis of transcription factor activities in environments with stable and dynamic oxygen concentrations by Rolfe, Matthew D., Ocone, Andrea, Stapleton, Melanie R., Hall, Simon, Trotter, Eleanor W., Poole, Robert K., Sanguinetti, Guido, Green, Jeffrey

“…Understanding gene regulation requires knowledge of changes in transcription factor (TF) activities. Simultaneous direct measurement of numerous TF activities…”
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The Di-Iron Protein YtfE Is a Nitric Oxide-Generating Nitrite Reductase Involved in the Management of Nitrosative Stress by Crack, Jason C, Balasiny, Basema K, Bennett, Sophie P, Rolfe, Matthew D, Froes, Afonso, MacMillan, Fraser, Green, Jeffrey, Cole, Jeffrey A, Le Brun, Nick E

“…Previously characterized nitrite reductases fall into three classes: siroheme-containing enzymes (NirBD), cytochrome c hemoproteins (NrfA and NirS), and…”
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The mechanism of a formaldehyde-sensing transcriptional regulator by Denby, Katie J., Iwig, Jeffrey, Bisson, Claudine, Westwood, Jodie, Rolfe, Matthew D., Sedelnikova, Svetlana E., Higgins, Khadine, Maroney, Michael J., Baker, Patrick J., Chivers, Peter T., Green, Jeffrey

“…Most organisms are exposed to the genotoxic chemical formaldehyde, either from endogenous or environmental sources. Therefore, biology has evolved systems to…”
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Adaptation of anaerobic cultures of Escherichia coliK-12 in response to environmental trimethylamine-N-oxide by Denby, Katie J, Rolfe, Matthew D, Crick, Ellen, Sanguinetti, Guido, Poole, Robert K, Green, Jeffrey

“…Summary Systematic analyses of transcriptional and metabolic changes occurring when Escherichia coliK-12 switches from fermentative growth to anaerobic…”
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Cmr is a redox-responsive regulator of DosR that contributes to M. tuberculosis virulence by Smith, Laura J, Bochkareva, Aleksandra, Rolfe, Matthew D, Hunt, Debbie M, Kahramanoglou, Christina, Braun, Yvonne, Rodgers, Angela, Blockley, Alix, Coade, Stephen, Lougheed, Kathryn E A, Hafneh, Nor Azian, Glenn, Sarah M, Crack, Jason C, Le Brun, Nick E, Saldanha, José W, Makarov, Vadim, Nobeli, Irene, Arnvig, Kristine, Mukamolova, Galina V, Buxton, Roger S, Green, Jeffrey

“…Mycobacterium tuberculosis (MTb) is the causative agent of pulmonary tuberculosis (TB). MTb colonizes the human lung, often entering a non-replicating state…”
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Three Pseudomonas putida FNR Family Proteins with Different Sensitivities to O2 by Ibrahim, Susan A., Crack, Jason C., Rolfe, Matthew D., Acuña, José Manuel Borrero-de, Thomson, Andrew J., Le Brun, Nick E., Schobert, Max, Stapleton, Melanie R., Green, Jeffrey

“…The Escherichia coli fumarate-nitrate reduction regulator (FNR) protein is the paradigm for bacterial O2-sensing transcription factors. However, unlike E…”
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Towards a systems level understanding of the oxygen response of Escherichia coli by Bettenbrock, Katja, Bai, Hao, Ederer, Michael, Green, Jeffrey, Hellingwerf, Klaas J, Holcombe, Michael, Kunz, Samantha, Rolfe, Matthew D, Sanguinetti, Guido, Sawodny, Oliver, Sharma, Poonam, Steinsiek, Sonja, Poole, Robert K

“…Escherichia coli is a facultatively anaerobic bacterium. With glucose if no external electron acceptors are available, ATP is produced by substrate level…”
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