Search Results - "Rolf Kreienberg"

Neoadjuvant Chemotherapy and Bevacizumab for HER2-Negative Breast Cancer by von Minckwitz, Gunter, Eidtmann, Holger, Rezai, Mahdi, Fasching, Peter A, Tesch, Hans, Eggemann, Holm, Schrader, Iris, Kittel, Kornelia, Hanusch, Claus, Kreienberg, Rolf, Solbach, Christine, Gerber, Bernd, Jackisch, Christian, Kunz, Georg, Blohmer, Jens-Uwe, Huober, Jens, Hauschild, Maik, Fehm, Tanja, Müller, Berit Maria, Denkert, Carsten, Loibl, Sibylle, Nekljudova, Valentina, Untch, Michael

“…Bevacizumab added to neoadjuvant combination chemotherapy increased the rate of pathological complete response among patients with HER-2-negative early-stage…”
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Pathologic Complete Response After Neoadjuvant Chemotherapy Plus Trastuzumab Predicts Favorable Survival in Human Epidermal Growth Factor Receptor 2–Overexpressing Breast Cancer: Results From the TECHNO Trial of the AGO and GBG Study Groups by UNTCH, Michael, FASCHING, Peter A, STICKELER, Elmar, HARBECK, Nadia, HÖSS, Cornelia, KAHLERT, Steffen, BECK, Thomas, FETT, Werner, MEHTA, Keyur M, VON MINCKWITZ, Gunter, LOIBL, Sibylle, KONECNY, Gottfried E, HASMÜLLER, Stephan, LEBEAU, Annette, KREIENBERG, Rolf, CAMARA, Oumar, MÜLLER, Volkmar, DU BOIS, Andreas, KÜHN, Thorsten

“…To evaluate efficacy and safety of epirubicin and cyclophosphamide followed by paclitaxel and trastuzumab as neoadjuvant treatment in patients with human…”
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Lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-taxane-based chemotherapy (GeparQuinto, GBG 44): a randomised phase 3 trial by Untch, Michael, Prof, Loibl, Sibylle, MD, Bischoff, Joachim, MD, Eidtmann, Holger, MD, Kaufmann, Manfred, Prof, Blohmer, Jens-Uwe, Prof, Hilfrich, Jörn, Prof, Strumberg, Dirk, Prof, Fasching, Peter A, Prof, Kreienberg, Rolf, Prof, Tesch, Hans, Prof, Hanusch, Claus, MD, Gerber, Bernd, Prof, Rezai, Mahdi, MD, Jackisch, Christian, Prof, Huober, Jens, Prof, Kühn, Thorsten, Prof, Nekljudova, Valentina, PhD, von Minckwitz, Gunter, Prof

“…Summary Background We compared the efficacy and safety of the addition of lapatinib versus trastuzumab to anthracycline-taxane-based neoadjuvant chemotherapy…”
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Does chemotherapy improve survival in patients with nodal positive luminal A breast cancer? A retrospective Multicenter Study by Herr, Daniel, Wischnewsky, Manfred, Joukhadar, Ralf, Chow, Olivia, Janni, Wolfgang, Leinert, Elena, Fink, Visnja, Stüber, Tanja, Curtaz, Carolin, Kreienberg, Rolf, Blettner, Maria, Wollschläger, Daniel, Wöckel, Achim

“…In this study based on the BRENDA data, we investigated the impact of endocrine ± chemotherapy for luminal A, nodal positive breast cancer on recurrence free…”
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Effect of adjuvant radiotherapy in elderly patients with breast cancer by Stueber, Tanja Nadine, Diessner, Joachim, Bartmann, Catharina, Leinert, Elena, Janni, Wolfgang, Herr, Daniel, Kreienberg, Rolf, Woeckel, Achim, Wischnewsky, Manfred

“…Radiotherapy (RT) is of critical importance in the locoregional management of early breast cancer. Although RT is routinely used following breast conserving…”
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Phase III Trial of Sunitinib in Combination With Capecitabine Versus Capecitabine Monotherapy for the Treatment of Patients With Pretreated Metastatic Breast Cancer by CROWN, John P, DIERAS, Véronique, GREIL, Richard, COGNETTI, Francesco, FOUNTZILAS, George, BLASINSKA-MORAWIEC, Maria, LIEDTKE, Cornelia, KREIENBERG, Rolf, MILLER, Wilson H, TASSELL, Vanessa, XIN HUANG, PAOLINI, Jolanda, STAROSLAWSKA, Elzbieta, KERN, Kenneth A, ROMIEU, Gilles, YARDLEY, Denise A, BACHELOT, Thomas, DAVIDSON, Neville, WILDIERS, Hans, FASCHING, Peter A, CAPITAIN, Olivier, RAMOS, Manuel

“…Metastatic breast cancer (MBC) remains an incurable illness in the majority of cases, despite major therapeutic advances. This may be related to the ability of…”
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Intense Dose-Dense Sequential Chemotherapy With Epirubicin, Paclitaxel, and Cyclophosphamide Compared With Conventionally Scheduled Chemotherapy in High-Risk Primary Breast Cancer: Mature Results of an AGO Phase III Study by MOEBUS, Volker, JACKISCH, Christian, HARBECK, Nadia, VON MINCKWITZ, Gunter, RUNNEBAUM, Ingo B, HINKE, Axel, KREIENBERG, Rolf, KONECNY, Gottfried E, UNTCH, Michael, LUECK, Hans-Joachim, DU BOIS, Andreas, THOMSSEN, Christoph, KURBACHER, Christian, KUHN, Walther, NITZ, Ulrike, SCHNEEWEISS, Andreas, HUOBER, Jens

“…Patients with primary breast cancer who have extensive axillary lymph node involvement have a poor prognosis after conventional adjuvant therapy. We compared…”
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Does the number of removed axillary lymphnodes in high risk breast cancer patients influence the survival? by Ebner, Florian, Wöckel, Achim, Schwentner, Lukas, Blettner, Maria, Janni, Wolfgang, Kreienberg, Rolf, Wischnewsky, Manfred

“…The decision making process for axillary dissection has changed in recent years for patients with early breast cancer and positive sentinel lymph nodes (LN)…”
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German Adjuvant Intergroup Node-Positive Study: A Phase III Trial to Compare Oral Ibandronate Versus Observation in Patients With High-Risk Early Breast Cancer by von Minckwitz, Gunter, Möbus, Volker, Schneeweiss, Andreas, Huober, Jens, Thomssen, Christoph, Untch, Michael, Jackisch, Christian, Diel, Ingo J., Elling, Dirk, Conrad, Bettina, Kreienberg, Rolf, Müller, Volkmar, Lück, Hans-Joachim, Bauerfeind, Ingo, Clemens, Michael, Schmidt, Marcus, Noeding, Stefanie, Forstbauer, Helmut, Barinoff, Jana, Belau, Antje, Nekljudova, Valentina, Harbeck, Nadia, Loibl, Sibylle

“…Bisphosphonates prevent skeletal-related events in patients with metastatic breast cancer. Their effect in early breast cancer is controversial. Ibandronate is…”
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Sentinel lymph node dissection only versus complete axillary lymph node dissection in early invasive breast cancer: A systematic review and meta-analysis by Glechner, Anna, Wöckel, Achim, Gartlehner, Gerald, Thaler, Kylie, Strobelberger, Michaela, Griebler, Ursula, Kreienberg, Rolf

“…Abstract Background The Z0011-study, a landmark randomised controlled trial (RCT) challenged the benefits of complete axillary lymph node dissection (ALND)…”
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Survivors of primary breast cancer 5 years after surgery: follow-up care, long-term problems, and treatment regrets. Results of the prospective BRENDA II-study by Leinert, Elena, Kreienberg, Rolf, Wöckel, Achim, Kühn, Thorsten, Flock, Felix, Felberbaum, Ricardo, Janni, Wolfgang, Taylor, Kathy, Singer, Susanne, Schwentner, Lukas

“…Purpose This study aims to answer the questions where breast cancer patients in Germany receive follow-up care (with what types of doctors) and what are the…”
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Intensive Dose-Dense Compared With Conventionally Scheduled Preoperative Chemotherapy for High-Risk Primary Breast Cancer by UNTCH, Michael, MÖBUS, Volker, KAHLERT, Stephen, VON KOCH, Franz, PETRY, Karl Ulrich, WALLWIENER, Diethelm, KREIENBERG, Rolf, ALBERT, Ute-Susann, LÜCK, Hans-Joachim, HINKE, Axel, JÄNICKE, Fritz, KONECNY, Gottfried E, KUHN, Walther, MUCK, Bernd Rudolph, THOMSSEN, Christoph, BAUERFEIND, Ingo, HARBECK, Nadia, WERNER, Christoph, LEBEAU, Annette, SCHNEEWEISS, Andreas

“…To compare preoperative intense dose-dense (IDD) chemotherapy with conventionally scheduled preoperative chemotherapy in high-risk primary breast cancer (BC)…”
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Do Patients with Luminal A Breast Cancer Profit from Adjuvant Systemic Therapy? A Retrospective Multicenter Study by Diessner, Joachim, Wischnewsky, Manfred, Blettner, Maria, Häusler, Sebastian, Janni, Wolfgang, Kreienberg, Rolf, Stein, Roland, Stüber, Tanja, Schwentner, Lukas, Bartmann, Catharina, Wöckel, Achim

“…Luminal A breast cancers respond well to anti-hormonal therapy (HT), are associated with a generally favorable prognosis and constitute the majority of breast…”
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Links between DNA double strand break repair and breast cancer: Accumulating evidence from both familial and nonfamilial cases by Ralhan, Ranju, Kaur, Jatinder, Kreienberg, Rolf, Wiesmüller, Lisa

“…Abstract DNA double strand break (DSB) repair dysfunction increases the risk of familial and sporadic breast cancer. Advances in the understanding of genetic…”
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Outcome analysis of primary breast cancer patients who declined adjuvant chemotherapy—results from the prospective multi-center BRENDA II study by Leinert, Elena, Schwentner, Lukas, Janni, Wolfgang, Wöckel, Achim, Herbert, Saskia-L., Herr, Daniel, Kühn, Thorsten, Flock, Felix, Felberbaum, Ricardo, Kreienberg, Rolf, Fink, Visnja, Dayan, Davut, Ernst, Kristina, Singer, Susanne

“…Background This study examined 5-year overall, recurrence and distant metastasis-free survival (OS, RFS, MFS) of high- and intermediate-risk breast cancer (BC)…”
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Phase III Study of Gemcitabine Plus Docetaxel Compared With Capecitabine Plus Docetaxel for Anthracycline-Pretreated Patients With Metastatic Breast Cancer by CHAN, Stephen, ROMIEU, Gilles, MAYORDOMO, Jose Ignacio, ANTON, Antonio, HARRISON, Mark, JONES, Alison, CARRASCO, Eva, THAREAU VAURY, A, FRIMODT-MOLLER, Bente, FUMOLEAU, Pierre, HUOBER, Jens, DELOZIER, Thierry, TUBIANA-HULIN, Michele, SCHNEEWEISS, Andreas, LLUCH, Ana, LLOMBART, Antonio, DU BOIS, Andreas, KREIENBERG, Rolf

“…Patients with metastatic breast cancer who are pretreated with anthracyclines frequently receive taxane-based combinations. This phase III study compared the…”
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Human chorionic gonadotropin controls luteal vascular permeability via vascular endothelial growth factor by down-regulation of a cascade of adhesion proteins by Herr, Daniel, M.D, Fraser, Hamish M., Ph.D, Konrad, Regina, B.S, Holzheu, Iris, B.S, Kreienberg, Rolf, Ph.D, Wulff, Christine, Ph.D

“…Objective To study the functional interactions of junctional proteins acting as regulators of vascular permeability in the human corpus luteum. We investigated…”
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First-Line Trastuzumab Plus Epirubicin and Cyclophosphamide Therapy in Patients With Human Epidermal Growth Factor Receptor 2–Positive Metastatic Breast Cancer: Cardiac Safety and Efficacy Data From the Herceptin, Cyclophosphamide, and Epirubicin (HERCULES) Trial by UNTCH, Michael, MUSCHOLL, Michael, HARBECK, Nadia, JACKISCH, Christian, MÜLLER, Volkmar, PAUSCHINGER, Matthias, THOMSSEN, Christoph, LEHLE, Michaela, CATALANI, Olivier, LÜCK, Hans-Joachim, TJULANDIN, Sergei, JONAT, Walter, MEERPOHL, Hans-Gerd, LICHINITSER, Mikhail, MANIKHAS, Alexey G, COUMBOS, Alexandra, KREIENBERG, Rolf, DU BOIS, Andreas

“…A high incidence of congestive heart failure (CHF) has been observed in patients with metastatic breast cancer (MBC) receiving doxorubicin-based chemotherapy…”
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Does guideline-adherent therapy improve the outcome for early-onset breast cancer patients? by Varga, Dominic, Wischnewsky, Manfred, Atassi, Ziad, Wolters, Regine, Geyer, Verena, Strunz, Kathrin, Kreienberg, Rolf, Woeckel, Achim

“…Guidelines for the treatment of early-onset breast cancer have been proposed in several countries, but to date, their impact on outcomes is unverified. The…”
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Radiotherapy effects on early breast cancer survival in observational and randomized studies: a systematic analysis of advantages, disadvantages and differences between the two study types by König, Jochem, van Ewijk, Reyn, Kuhr, Kathrin, Schmidberger, Heinz, Wöckel, Achim, Kreienberg, Rolf, Blettner, Maria

“…Aim Treatment–outcome associations often differ substantially between observational studies (OSs) and randomized controlled trials (RCTs). We investigate…”
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