Search Results - "Role, Lorna W"

Basal Forebrain Cholinergic Circuits and Signaling in Cognition and Cognitive Decline by Ballinger, Elizabeth C., Ananth, Mala, Talmage, David A., Role, Lorna W.

“…Recent work continues to place cholinergic circuits at center stage for normal executive and mnemonic functioning and provides compelling evidence that the…”
Get full text

Cholinergic Signaling Controls Conditioned Fear Behaviors and Enhances Plasticity of Cortical-Amygdala Circuits by Jiang, Li, Kundu, Srikanya, Lederman, James D., López-Hernández, Gretchen Y., Ballinger, Elizabeth C., Wang, Shaohua, Talmage, David A., Role, Lorna W.

“…We examined the contribution of endogenous cholinergic signaling to the acquisition and extinction of fear- related memory by optogenetic regulation of…”
Get full text

Distinct subpopulations of ventral pallidal cholinergic projection neurons encode valence of olfactory stimuli by Kim, Ronald, Ananth, Mala R., Desai, Niraj S., Role, Lorna W., Talmage, David A.

“…To better understand the function of cholinergic projection neurons in the ventral pallidum (VP), we examined behavioral responses to appetitive (APP) and…”
Get full text

Acetylcholine is released in the basolateral amygdala in response to predictors of reward and enhances the learning of cue-reward contingency by Crouse, Richard B, Kim, Kristen, Batchelor, Hannah M, Girardi, Eric M, Kamaletdinova, Rufina, Chan, Justin, Rajebhosale, Prithviraj, Pittenger, Steven T, Role, Lorna W, Talmage, David A, Jing, Miao, Li, Yulong, Gao, Xiao-Bing, Mineur, Yann S, Picciotto, Marina R

“…The basolateral amygdala (BLA) is critical for associating initially neutral cues with appetitive and aversive stimuli and receives dense neuromodulatory…”
Get full text

Nicotine elicits prolonged calcium signaling along ventral hippocampal axons by Zhong, Chongbo, Talmage, David A, Role, Lorna W

“…Presynaptic nicotinic acetylcholine receptors (nAChRs) have long been implicated in the modulation of CNS circuits. We previously reported that brief exposure…”
Get full text

Axonal α7 nicotinic acetylcholine receptors modulate glutamatergic signaling and synaptic vesicle organization in ventral hippocampal projections by Zhong, Chongbo, Akmentin, Wendy, Role, Lorna W, Talmage, David A

“…Modulation of the release of glutamate by activation of presynaptic nicotinic acetylcholine receptors (nAChRs) is one of the most prevalent mechanism of…”
Get full text

Functionally refined encoding of threat memory by distinct populations of basal forebrain cholinergic projection neurons by Rajebhosale, Prithviraj, Ananth, Mala R, Kim, Ronald, Crouse, Richard, Jiang, Li, López-Hernández, Gretchen, Zhong, Chongbo, Arty, Christian, Wang, Shaohua, Jone, Alice, Desai, Niraj S, Li, Yulong, Picciotto, Marina R, Role, Lorna W, Talmage, David A

“…Neurons of the basal forebrain nucleus basalis and posterior substantia innominata (NBM/SI ) comprise the major source of cholinergic input to the basolateral…”
Get full text

Tangential Neuronal Migration Controls Axon Guidance: A Role for Neuregulin-1 in Thalamocortical Axon Navigation by López-Bendito, Guillermina, Cautinat, Aline, Sánchez, Juan Antonio, Bielle, Franck, Flames, Nuria, Garratt, Alistair N., Talmage, David A., Role, Lorna W., Charnay, Patrick, Marín, Oscar, Garel, Sonia

“…Neuronal migration and axon guidance constitute fundamental processes in brain development that are generally studied independently. Although both share common…”
Get full text

Facilitation of Cortico-Amygdala Synapses by Nicotine: Activity-Dependent Modulation of Glutamatergic Transmission by Jiang, Li, Role, Lorna W

“…1 Center for Neurobiology and Behavior, Columbia University College of Physicians & Surgeons; and 2 Research Foundation for Mental Health, New York State…”
Get full text

Integration of Endocannabinoid and Leptin Signaling in an Appetite-Related Neural Circuit by Jo, Young-Hwan, Chen, Ying-Jiun J., Chua, Streamson C., Talmage, David A., Role, Lorna W.

“…Recently developed therapeutics for obesity, targeted against cannabinoid receptors, result in decreased appetite and sustained weight loss. Prior studies have…”
Get full text

Back Signaling by the Nrg-1 Intracellular Domain by Bao, Jianxin, Wolpowitz, Deon, Role, Lorna W., Talmage, David A.

“…Transmembrane isoforms of neuregulin-1 (Nrg-1), ligands for erbB receptors, include an extracellular domain with an EGF-like sequence and a highly conserved…”
Get full text

Illuminating the role of cholinergic signaling in circuits of attention and emotionally salient behaviors by Luchicchi, Antonio, Bloem, Bernard, Viaña, John Noel M, Mansvelder, Huibert D, Role, Lorna W

“…Acetylcholine (ACh) signaling underlies specific aspects of cognitive functions and behaviors, including attention, learning, memory and motivation…”
Get full text

Disrupted Activity in the Hippocampal-Accumbens Circuit of Type III Neuregulin 1 Mutant Mice by Nason, Jr, Malcolm W, Adhikari, Avishek, Bozinoski, Marjan, Gordon, Joshua A, Role, Lorna W

“…Neuregulin 1 (Nrg1), a schizophrenia susceptibility gene, is involved in fundamental aspects of neurodevelopment. Mice lacking any one of the several isoforms…”
Get full text

Presynaptic ionotropic receptors and the control of transmitter release by MACDERMOTT, A. B, ROLE, L. W, SIEGELBAUM, S. A

“…The quantity of neurotransmitter released into the synaptic cleft, the reliability with which it is released, and the response of the postsynaptic cell to that…”
Get full text

Nicotinic Receptors in the Development and Modulation of CNS Synapses by Role, Lorna W, Berg, Darwin K

“…The molecular dissection of muscle-type nicotinic acetylcholine receptors (nAChRs) with gene cloning techniques set the stage for similar analyses of…”
Get full text

Overnight fasting regulates inhibitory tone to cholinergic neurons of the dorsomedial nucleus of the hypothalamus by Groessl, Florian, Jeong, Jae Hoon, Talmage, David A, Role, Lorna W, Jo, Young-Hwan

“…The dorsomedial nucleus of the hypothalamus (DMH) contributes to the regulation of overall energy homeostasis by modulating energy intake as well as energy…”
Get full text

Type III Nrg1 back signaling enhances functional TRPV1 along sensory axons contributing to basal and inflammatory thermal pain sensation by Canetta, Sarah E, Luca, Edlira, Pertot, Elyse, Role, Lorna W, Talmage, David A

“…Type III Nrg1, a member of the Nrg1 family of signaling proteins, is expressed in sensory neurons, where it can signal in a bi-directional manner via…”
Get full text

Cysteine-rich domain isoforms of the neuregulin-1 gene are required for maintenance of peripheral synapses by Wolpowitz, D, Mason, T B, Dietrich, P, Mendelsohn, M, Talmage, D A, Role, L W

“…Neuregulin-1 (NRG-1) signaling has been implicated in inductive interactions between pre- and postsynaptic partners during synaptogenesis. We used gene…”
Get full text

A genetically encoded fluorescent acetylcholine indicator for in vitro and in vivo studies by Jing, Miao, Zhang, Peng, Wang, Guangfu, Feng, Jiesi, Mesik, Lukas, Zeng, Jianzhi, Jiang, Huoqing, Wang, Shaohua, Looby, Jess C, Guagliardo, Nick A, Langma, Linda W, Lu, Ju, Zuo, Yi, Talmage, David A, Role, Lorna W, Barrett, Paula Q, Zhang, Li I, Luo, Minmin, Song, Yan, Zhu, J Julius, Li, Yulong

“…The neurotransmitter acetylcholine (ACh) regulates a diverse array of physiological processes throughout the body. Despite its importance, cholinergic…”
Get full text

Basal forebrain cholinergic signalling: development, connectivity and roles in cognition by Ananth, Mala R., Rajebhosale, Prithviraj, Kim, Ronald, Talmage, David A., Role, Lorna W.

“…Acetylcholine plays an essential role in fundamental aspects of cognition. Studies that have mapped the activity and functional connectivity of cholinergic…”
Get full text