Search Results - "Roldan, Miren"

Gender-Dependent Deregulation of Linear and Circular RNA Variants of HOMER1 in the Entorhinal Cortex of Alzheimer’s Disease by Urdánoz-Casado, Amaya, Sánchez-Ruiz de Gordoa, Javier, Robles, Maitane, Acha, Blanca, Roldan, Miren, Zelaya, María Victoria, Blanco-Luquin, Idoia, Mendioroz, Maite

“…The HOMER1 gene is involved in synaptic plasticity, learning and memory. Recent studies show that circular RNA derived from HOMER1 (circHOMER1) expression is…”
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circRNA from APP Gene Changes in Alzheimer's Disease Human Brain by Urdánoz-Casado, Amaya, Sánchez-Ruiz de Gordoa, Javier, Robles, Maitane, Roldan, Miren, Macías Conde, Mónica, Acha, Blanca, Blanco-Luquin, Idoia, Mendioroz, Maite

“…Alzheimer's disease (AD) is the most common cause of age-related dementia. Amyloid precursor protein ( ) is the precursor of Aβ peptides, and its role in AD…”
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Profile of TREM2-Derived circRNA and mRNA Variants in the Entorhinal Cortex of Alzheimer’s Disease Patients by Urdánoz-Casado, Amaya, de Gordoa, Javier Sánchez-Ruiz, Robles, Maitane, Roldan, Miren, Zelaya, María Victoria, Blanco-Luquin, Idoia, Mendioroz, Maite

“…Genetic variants in TREM2, a microglia-related gene, are well-known risk factors for Alzheimer’s disease (AD). Here, we report that TREM2 originates from…”
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Exploring the Disease-Associated Microglia State in Amyotrophic Lateral Sclerosis by Jauregui, Carlota, Blanco-Luquin, Idoia, Macías, Mónica, Roldan, Miren, Caballero, Cristina, Pagola, Inma, Mendioroz, Maite, Jericó, Ivonne

“…Background: Neuroinflammation, and specifically microglia, plays an important but not-yet well-understood role in the pathophysiology of amyotrophic lateral…”
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Liquid Biopsy in Alzheimer's Disease Patients Reveals Epigenetic Changes in the PRLHR Gene by Macías, Mónica, Acha, Blanca, Corroza, Jon, Urdánoz-Casado, Amaya, Roldan, Miren, Robles, Maitane, Sánchez-Ruiz de Gordoa, Javier, Erro, María Elena, Jericó, Ivonne, Blanco-Luquin, Idoia, Mendioroz, Maite

“…In recent years, new DNA methylation variants have been reported in genes biologically relevant to Alzheimer's disease (AD) in human brain tissue. However,…”
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NXN Gene Epigenetic Changes in an Adult Neurogenesis Model of Alzheimer's Disease by Blanco-Luquin, Idoia, Acha, Blanca, Urdánoz-Casado, Amaya, Gómez-Orte, Eva, Roldan, Miren, Pérez-Rodríguez, Diego R, Cabello, Juan, Mendioroz, Maite

“…In view of the proven link between adult hippocampal neurogenesis (AHN) and learning and memory impairment, we generated a straightforward adult neurogenesis…”
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Telomere length correlates with subtelomeric DNA methylation in long-term mindfulness practitioners by Mendioroz, Maite, Puebla-Guedea, Marta, Montero-Marín, Jesús, Urdánoz-Casado, Amaya, Blanco-Luquin, Idoia, Roldán, Miren, Labarga, Alberto, García-Campayo, Javier

“…Mindfulness and meditation techniques have proven successful for the reduction of stress and improvement in general health. In addition, meditation is linked…”
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Profiling TREM2 expression in amyotrophic lateral sclerosis by Jericó, Ivonne, Vicuña-Urriza, Janire, Blanco-Luquin, Idoia, Macias, Mónica, Martinez-Merino, Leyre, Roldán, Miren, Rojas-Garcia, Ricard, Pagola-Lorz, Inmaculada, Carbayo, Alvaro, De Luna, Noemi, Zelaya, Victoria, Mendioroz, Maite

“…•TREM2 is involved in pathophisiology of amyotrophic lateral sclerosis (ALS).•All the TREM2 transcripts analysed are deregulated in ALS spinal cord.•Soluble…”
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Vitamin D receptor gene is epigenetically altered and transcriptionally up-regulated in multiple sclerosis by Ayuso, Teresa, Aznar, Patricia, Soriano, Luis, Olaskoaga, Ander, Roldán, Miren, Otano, María, Ajuria, Iratxe, Soriano, Gerardo, Lacruz, Francisco, Mendioroz, Maite

“…Vitamin D deficiency has been linked to increased risk of multiple sclerosis (MS) and poor outcome. However, the specific role that vitamin D plays in MS still…”
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Circular RNA expression profile in blood according to ischemic stroke etiology by Ostolaza, Aiora, Blanco-Luquin, Idoia, Urdánoz-Casado, Amaya, Rubio, Idoya, Labarga, Alberto, Zandio, Beatriz, Roldán, Miren, Martínez-Cascales, Judith, Mayor, Sergio, Herrera, María, Aymerich, Nuria, Gallego, Jaime, Muñoz, Roberto, Mendioroz, Maite

“…The discovery of novel biomarkers of stroke etiology would be most helpful in management of acute ischemic stroke patients. Recently, circular RNAs (circRNAs)…”
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Early epigenetic changes of Alzheimer's disease in the human hippocampus by Blanco-Luquin, Idoia, Acha, Blanca, Urdánoz-Casado, Amaya, Sánchez-Ruiz De Gordoa, Javier, Vicuña-Urriza, Janire, Roldán, Miren, Labarga, Alberto, Zelaya, María Victoria, Cabello, Carolina, Méndez-López, Iván, Mendioroz, Maite

“…The discovery of new biomarkers would be very valuable to improve the detection of early Alzheimer's disease (AD). DNA methylation marks may serve as…”
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Is the Phenotype Designation by PSP-MDS Criteria Stable Throughout the Disease Course and Consistent With Tau Distribution? by Sánchez-Ruiz de Gordoa, Javier, Zelaya, Victoria, Tellechea-Aramburo, Paula, Acha, Blanca, Roldán, Miren, López-Molina, Carlos, Coca, Valle, Galbete, Arkaitz, Mendioroz, Maite, Erro, M Elena

“…The MDS-PSP criteria have shown high sensitivity for the PSP diagnosis, but do not discriminate the phenotype diversity. Our purpose was to search for…”
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Hippocampal LMNA Gene Expression is Increased in Late-Stage Alzheimer's Disease by Méndez-López, Iván, Blanco-Luquin, Idoia, Sánchez-Ruiz de Gordoa, Javier, Urdánoz-Casado, Amaya, Roldán, Miren, Acha, Blanca, Echavarri, Carmen, Zelaya, Victoria, Jericó, Ivonne, Mendioroz, Maite

“…Lamins are fibrillary proteins that are crucial in maintaining nuclear shape and function. Recently, B-type lamin dysfunction has been linked to tauopathies…”
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Mass Spectrometry-Based Proteomic Profiling of Thrombotic Material Obtained by Endovascular Thrombectomy in Patients with Ischemic Stroke by Muñoz, Roberto, Santamaría, Enrique, Rubio, Idoya, Ausín, Karina, Ostolaza, Aiora, Labarga, Alberto, Roldán, Miren, Zandio, Beatriz, Mayor, Sergio, Bermejo, Rebeca, Mendigaña, Mónica, Herrera, María, Aymerich, Nuria, Olier, Jorge, Gállego, Jaime, Mendioroz, Maite, Fernández-Irigoyen, Joaquín

“…Thrombotic material retrieved from acute ischemic stroke (AIS) patients represents a valuable source of biological information. In this study, we have…”
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DNA methylation signature of human hippocampus in Alzheimer's disease is linked to neurogenesis by Altuna, Miren, Urdánoz-Casado, Amaya, Sánchez-Ruiz de Gordoa, Javier, Zelaya, María V, Labarga, Alberto, Lepesant, Julie M J, Roldán, Miren, Blanco-Luquin, Idoia, Perdones, Álvaro, Larumbe, Rosa, Jericó, Ivonne, Echavarri, Carmen, Méndez-López, Iván, Di Stefano, Luisa, Mendioroz, Maite

“…Drawing the epigenome landscape of Alzheimer's disease (AD) still remains a challenge. To characterize the epigenetic molecular basis of the human hippocampus…”
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TREM2 upregulation correlates with 5-hydroxymethycytosine enrichment in Alzheimer's disease hippocampus by Celarain, Naiara, Sánchez-Ruiz de Gordoa, Javier, Zelaya, María Victoria, Roldán, Miren, Larumbe, Rosa, Pulido, Laura, Echavarri, Carmen, Mendioroz, Maite

“…Recent genome-wide association studies revealed TREM2 rs75932628-T variant to be associated with Alzheimer's disease (AD) and other neurodegenerative diseases…”
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Microglia‐Related Gene Triggering Receptor Expressed in Myeloid Cells 2 (TREM2) Is Upregulated in the Substantia Nigra of Progressive Supranuclear Palsy by Sánchez‐Ruiz de Gordoa, Javier, Erro, María Elena, Vicuña‐Urriza, Janire, Zelaya, María Victoria, Tellechea, Paula, Acha, Blanca, Zueco, Sara, Urdánoz‐Casado, Amaya, Roldán, Miren, Blanco‐Luquin, Idoia, Mendioroz, Maite

“…Background The role of the microglia‐related gene triggering receptor expressed in myeloid cells 2 (TREM2) in primary tauopathies, such as progressive…”
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PLD3 epigenetic changes in the hippocampus of Alzheimer's disease by Blanco-Luquin, Idoia, Altuna, Miren, Sánchez-Ruiz de Gordoa, Javier, Urdánoz-Casado, Amaya, Roldán, Miren, Cámara, María, Zelaya, Victoria, Erro, María Elena, Echavarri, Carmen, Mendioroz, Maite

“…Whole-exome sequencing has revealed a rare missense variant in PLD3 gene (rs145999145) to be associated with late onset Alzheimer's disease (AD). Nevertheless,…”
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CRTC1 gene is differentially methylated in the human hippocampus in Alzheimer's disease by Mendioroz, Maite, Celarain, Naiara, Altuna, Miren, Sánchez-Ruiz de Gordoa, Javier, Zelaya, María Victoria, Roldán, Miren, Rubio, Idoya, Larumbe, Rosa, Erro, María Elena, Méndez, Iván, Echávarri, Carmen

“…CRTC1 (CREB regulated transcription coactivator 1) gene plays a role in synaptic plasticity, learning and long-term memory formation in the hippocampus…”
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Evaluation of Chitotriosidase and CC-Chemokine Ligand 18 as Biomarkers of Microglia Activation in Amyotrophic Lateral Sclerosis by Martinez-Merino, Leyre, Iridoy, Marina, Galbete, Arkaitz, Roldán, Miren, Rivero, Adriana, Acha, Blanca, Irún, Pilar, Canosa, Cecilia, Pocoví, Miguel, Mendioroz, Maite, Jericó, Ivonne

“…The development of biomarkers for use in diagnosing, monitoring disease progression and analyzing therapeutic trials response in amyotrophic lateral sclerosis…”
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