Search Results - "Roldán, Raquel"
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Cell death induced by Bothrops asper snake venom metalloproteinase on endothelial and other cell lines
Published in Experimental and molecular pathology (01-06-2010)“…Two adherent cell lines, BAEC and HeLa, and non-adherent Jurkat, were treated with snake venom metalloproteinase BaP1 to determine whether cytotoxicity,…”
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2
ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies
Published in Nature (London) (14-01-2021)“…Cardiovascular disease (CVD) is the leading cause of mortality in the world, with most CVD-related deaths resulting from myocardial infarction or stroke. The…”
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3
Breaking the Dogma of Aldolase Specificity: Simple Aliphatic Ketones and Aldehydes are Nucleophiles for Fructose‐6‐phosphate Aldolase
Published in Chemistry : a European journal (11-04-2017)“…d‐Fructose‐6‐phosphate aldolase (FSA) was probed for extended nucleophile promiscuity by using a series of fluorogenic substrates to reveal retro‐aldol…”
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4
Response of neuroblastoma cells to RF currents as a function of the signal frequency
Published in BMC cancer (05-09-2019)“…Capacitive-resistive electric transfer (CRET) is a non-invasive therapeutic strategy that applies radiofrequency electric currents within the 400-600 kHz range…”
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5
Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes
Published in ACS catalysis (07-09-2018)“…Asymmetric aldol addition of simple aldehydes and ketones to electrophiles is a cornerstone reaction for the synthesis of unusual sugars and chiral building…”
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Aldolase‐Catalyzed Asymmetric Synthesis of N‐Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes
Published in Advanced synthesis & catalysis (06-06-2019)“…Nitrogen heterocycles are structural motifs found in many bioactive natural products and of utmost importance in pharmaceutical drug development. In this work,…”
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Malondialdehyde-modified HDL particles elicit a specific IgG response in abdominal aortic aneurysm
Published in Free radical biology & medicine (01-10-2021)“…High Density Lipoprotein (HDL) plays a protective role in abdominal aortic aneurysm (AAA); however, recent findings suggest that oxidative modifications could…”
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8
Soda-anthraquinone pulping and cationization of Posidonia oceanica
Published in Bioresources (01-11-2019)“…Every year, millions of tonnes of dead biomass from algae and seagrasses are collected on the Mediterranean coasts. Posidonia oceanica is one of the most…”
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A PR-1-like Protein of Fusarium oxysporum Functions in Virulence on Mammalian Hosts
Published in The Journal of biological chemistry (22-06-2012)“…The pathogenesis-related PR-1-like protein family comprises secreted proteins from the animal, plant, and fungal kingdoms whose biological function remains…”
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10
Galectin-1 prevents pathological vascular remodeling in atherosclerosis and abdominal aortic aneurysm
Published in Science advances (18-03-2022)“…Pathological vascular remodeling is the underlying cause of atherosclerosis and abdominal aortic aneurysm (AAA). Here, we analyzed the role of galectin-1…”
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11
Disentangling Complex Mixtures of Compounds with Near-Identical 1H and 13C NMR Spectra using Pure Shift NMR Spectroscopy
Published in Chemistry : a European journal (18-05-2015)“…The thorough analysis of highly complex NMR spectra using pure shift NMR experiments is described. The enhanced spectral resolution obtained from modern 2D…”
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12
Disentangling Complex Mixtures of Compounds with Near-Identical (1) H and (13) C NMR Spectra using Pure Shift NMR Spectroscopy
Published in Chemistry : a European journal (18-05-2015)“…The thorough analysis of highly complex NMR spectra using pure shift NMR experiments is described. The enhanced spectral resolution obtained from modern 2D…”
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13
Factor H-Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy
Published in Journal of the American Society of Nephrology (01-06-2022)“…C3 glomerulopathy (C3G) is a heterogeneous group of chronic renal diseases characterized predominantly by glomerular C3 deposition and complement…”
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14
Disentangling Complex Mixtures of Compounds with Near‐Identical 1 H and 13 C NMR Spectra using Pure Shift NMR Spectroscopy
Published in Chemistry : a European journal (18-05-2015)“…The thorough analysis of highly complex NMR spectra using pure shift NMR experiments is described. The enhanced spectral resolution obtained from modern 2D…”
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15
APOA1 oxidation is associated to dysfunctional high-density lipoproteins in human abdominal aortic aneurysm
Published in EBioMedicine (01-05-2019)“…High-density lipoproteins (HDL) are a complex mixture of lipids and proteins with vasculoprotective properties. However, HDL components could suffer…”
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POR UMA ARQUEOLOGIA DOS ENVELHECIDOS: Aspectos Teóricos do Envelhecimento Humano
Published in Clio arqueológica (21-07-2022)“…Este artigo apresenta uma análise da relação das instâncias sociais, históricas, culturais e discursivas sobre os individuos envelhecidos com a produção do…”
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17
Pathophysiology of abdominal aortic aneurysm: biomarkers and novel therapeutic targets
Published in Clínica e investigación en arteriosclerosis (Internet, English ed.) (01-07-2019)“…Abdominal aortic aneurysm (AAA) is a vascular pathology with a high rate of morbidity and mortality and a prevalence that, in men over 65 years, can reach…”
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18
Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Aldol Products
Published in Angewandte Chemie International Edition (06-08-2018)“…A structure‐guided engineering of fructose‐6‐phosphate aldolase was performed to expand its substrate promiscuity toward aliphatic nucleophiles, that is,…”
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19
Disentangling Complex Mixtures of Compounds with Near-Identical 1H and 13CNMR Spectra using Pure Shift NMR Spectroscopy
Published in Chemistry : a European journal (18-05-2015)“…The thorough analysis of highly complex NMR spectra using pure shift NMR experiments is described. The enhanced spectral resolution obtained from modern 2D…”
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20
Disentangling Complex Mixtures of Compounds with Near-Identical super(1)H and super(13)CNMR Spectra using Pure Shift NMR Spectroscopy
Published in Chemistry : a European journal (01-05-2015)“…The thorough analysis of highly complex NMR spectra using pure shift NMR experiments is described. The enhanced spectral resolution obtained from modern 2D…”
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