Search Results - "Rolati, Sophie"

Identifying differential regulatory control of APOE ɛ4 on African versus European haplotypes as potential therapeutic targets by Nuytemans, Karen, Lipkin Vasquez, Marina, Wang, Liyong, Van Booven, Derek, Griswold, Antony J., Rajabli, Farid, Celis, Katrina, Oron, Oded, Hofmann, Natalia, Rolati, Sophie, Garcia‐Serje, Catherine, Zhang, Shanshan, Jin, Fulai, Argenziano, Mariana, Grant, Struan F.A., Chesi, Alessandra, Brown, Christopher D., Young, Juan I., Dykxhoorn, Derek M., Pericak‐Vance, Margaret A., Vance, Jeffery M.

“…We previously demonstrated that in Alzheimer's disease (AD) patients, European apolipoprotein E (APOE) ε4 carriers express significantly more APOE ε4 in their…”
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Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport by Kunkle, Brian W, Vardarajan, Badri N, Naj, Adam C, Whitehead, Patrice L, Rolati, Sophie, Slifer, Susan, Carney, Regina M, Cuccaro, Michael L, Vance, Jeffery M, Gilbert, John R, Wang, Li-San, Farrer, Lindsay A, Reitz, Christiane, Haines, Jonathan L, Beecham, Gary W, Martin, Eden R, Schellenberg, Gerard D, Mayeux, Richard P, Pericak-Vance, Margaret A

“…Mutations in APP, PSEN1, and PSEN2 lead to early-onset Alzheimer disease (EOAD) but account for only approximately 11% of EOAD overall, leaving most of the…”
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Identifying differential regulatory control of APOEɛ4 on African versus European haplotypes as potential therapeutic targets by Nuytemans, Karen, Vasquez, Marina Lipkin, Wang, Liyong, Van Booven, Derek, Griswold, Anthony J., Rajabli, Farid, Celis, Katrina, Oron, Oded, Hofmann, Natalia, Rolati, Sophie, Garcia-Serje, Catherine, Zhang, Shanshan, Jin, Fulai, Argenziano, Mariana, Grant, Struan F.A., Chesi, Alessandra, Brown, Christopher D., Young, Juan I., Dykxhoorn, Derek M., Pericak-Vance, Margaret A., Vance, Jeffery M.

“…We previously demonstrated that in Alzheimer’s disease (AD) patients, European apolipoprotein E ( APOE ) ε 4 carriers express significantly more APOEε 4 in…”
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MULTI-ETHNIC ALZHEIMER’S DISEASE RELATED CHANGES OF RNA EDITING AFFECT IMMUNE REGULATION, ENDOCYTOSIS, AND AMYLOID PRECURSOR PROTEIN CATABOLISM by Gardner, Olivia K., Wang, Lily, Whitehead, Patrice L., Hamilton-Nelson, Kara L., Adams, Larry D., Rolati, Sophie, Hofmann, Natalia K., Vance, Jeffery M., Cuccaro, Michael L., Bush, William S., Martin, Eden R., Byrd, Goldie S., Haines, Jonathan L., Beecham, Gary W., Pericak-Vance, Margaret A., Griswold, Anthony J.

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P1‐144: TRANSCRIPTOMIC ANALYSIS OF WHOLE BLOOD IN AFRICAN AMERICAN AND NON‐HISPANIC WHITE ALZHEIMER DISEASE CASES AND CONTROLS by Griswold, Anthony J., Sivasankaran, Sathesh K., Gardner, Olivia K., Rajabli, Farid, Hamilton-Nelson, Kara L., Rolati, Sophie, Hofmann, Natalia K., Whitehead, Patrice L., Adams, Larry D., Byrd, Goldie S., Martin, Eden R., Cuccaro, Michael L., Bush, William S., Haines, Jonathan L., Vance, Jeffery M., Beecham, Gary W., Pericak-Vance, Margaret A.

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O3‐06‐06: IDENTIFYING A PROTECTIVE VARIANT THAT LOWERS THE RISK FOR DEVELOPING AD IN APOE‐E4 CARRIERS by Rajabli, Farid, Vance, Jeffery M., Feliciano-Astacio, Briseida E., Celis, Katrina, Adams, Larry D., Hamilton-Nelson, Kara L., Wang, Liyong, Nuytemans, Karen, Whitehead, Patrice L., Hofmann, Natalia K., Rolati, Sophie, Haines, Jonathan L., Byrd, Goldie S., Reitz, Christiane, Beecham, Gary W., Pericak-Vance, Margaret A.

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IDENTIFYING A PROTECTIVE VARIANT THAT LOWERS THE RISK FOR DEVELOPING AD IN APOE-E4 CARRIERS by Rajabli, Farid, Vance, Jeffery M., Feliciano-Astacio, Briseida E., Celis, Katrina, Adams, Larry D., Hamilton-Nelson, Kara L., Wang, Liyong, Nuytemans, Karen, Whitehead, Patrice L., Hofmann, Natalia K., Rolati, Sophie, Haines, Jonathan L., Byrd, Goldie S., Reitz, Christiane, Beecham, Gary W., Pericak-Vance, Margaret A.

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TRANSCRIPTOMIC ANALYSIS OF WHOLE BLOOD IN AFRICAN AMERICAN AND NON-HISPANIC WHITE ALZHEIMER DISEASE CASES AND CONTROLS by Griswold, Anthony J., Sivasankaran, Sathesh K., Gardner, Olivia K., Rajabli, Farid, Hamilton-Nelson, Kara L., Rolati, Sophie, Hofmann, Natalia K., Whitehead, Patrice L., Adams, Larry D., Byrd, Goldie S., Martin, Eden R., Cuccaro, Michael L., Bush, William S., Haines, Jonathan L., Vance, Jeffery M., Beecham, Gary W., Pericak-Vance, Margaret A.

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O2‐01‐05: MULTI‐ETHNIC ALZHEIMER'S DISEASE RELATED CHANGES OF RNA EDITING AFFECT IMMUNE REGULATION, ENDOCYTOSIS, AND AMYLOID PRECURSOR PROTEIN CATABOLISM by Gardner, Olivia K., Wang, Lily, Whitehead, Patrice L., Hamilton-Nelson, Kara L., Adams, Larry D., Rolati, Sophie, Hofmann, Natalia K., Vance, Jeffery M., Cuccaro, Michael L., Bush, William S., Martin, Eden R., Byrd, Goldie S., Haines, Jonathan L., Beecham, Gary W., Pericak-Vance, Margaret A., Griswold, Anthony J.

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O3‐13‐02: Whole‐exome sequencing in early‐onset Alzheimer disease cases identifies novel candidate genes by Beecham, Gary W., Kunkle, Brian W., Vardarajan, Badri, Whitehead, Patrice L., Rolati, Sophie, Martin, Eden R., Gilbert, John R., Mayeux, Richard, Haines, Jonathan L., Pericak-Vance, Margaret A.

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O1‐09‐02: Whole Exome Sequencing of Late Onset Multiplex Families Identifies Rare Coding Variants in Known and Novel Alzheimer’s Disease Genes by Cukier, Holly N., Kunkle, Brian W., Rolati, Sophie, Whitehead, Patrice L., Vance, Jeffery M., Cuccaro, Michael L., Carney, Regina M., Gilbert, John R., Martin, Eden R., Beecham, Gary W., Haines, Jonathan L., Pericak-Vance, Margaret A., Hamilton-Nelson, Kara L.

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PATIENT-DERIVED IPSC MODEL OF AN ABCA7 FRAMESHIFT DELETION ASSOCIATED WITH ALZHEIMER’S DISEASE IN AFRICAN AMERICANS by Cukier, Holly N., Mehta, Neil, Ramirez, Juliana, Rolati, Sophie, Whitehead, Patrice L., Adams, Larry Deon, Celis, Katrina, Carney, Regina, Vance, Jeffery M., Cuccaro, Michael L., Byrd, Goldie S., Pericak-Vance, Margaret A., Dykxhoorn, Derek M.

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O1‐03‐03: Identification of Novel Candidate Genes for Early‐Onset Alzheimer's Disease Through Integrated Whole‐Exome Sequencing and Exome Chip Array Association Analysis by Kunkle, Brian W., Vardarajan, Badri N., Naj, Adam C., Cukier, Holly N., Dykxhoorn, Derek M., Rolati, Sophie, Whitehead, Patrice L., Carney, Regina M., Cuccaro, Michael L., Vance, Jeffery M., Genetics Consortium, Alzheimer's Disease, Farrer, Lindsay A., Haines, Jonathan L., Schellenberg, Gerard D., Martin, Eden R., Reitz, Christiane, Beecham, Gary W., Mayeux, Richard, Pericak-Vance, Margaret A.

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O1‐03‐02: ABCA7 Frameshift Deletion Associated with Alzheimer’s Disease in African Americans by Dykxhoorn, Derek M., Cukier, Holly N., Kunkle, Brian W., Vardarajan, Badri N., Rolati, Sophie, Hamilton-Nelson, Kara L., Kohli, Martin A., Whitehead, Patrice L., Van Booven, Derek J., Lang, Rosalyn, Farrer, Lindsay A., Cuccaro, Michael L., Vance, Jeffery M., Gilbert, John R., Beecham, Gary W., Martin, Eden R., Carney, Regina M., Mayeux, Richard, Schellenberg, Gerard D., Byrd, Goldie S., Haines, Jonathan L., Pericak-Vance, Margaret A.

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Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease by Kohli, Martin A, Cukier, Holly N, Hamilton-Nelson, Kara L, Rolati, Sophie, Kunkle, Brian W, Whitehead, Patrice L, Züchner, Stephan L, Farrer, Lindsay A, Martin, Eden R, Beecham, Gary W, Haines, Jonathan L, Vance, Jeffery M, Cuccaro, Michael L, Gilbert, John R, Schellenberg, Gerard D, Carney, Regina M, Pericak-Vance, Margaret A

“…The genetic risk architecture of Alzheimer disease (AD) is complex with single pathogenic mutations leading to early-onset AD, while both rare and common…”
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WHOLE EXOME SEQUENCING OF LATE ONSET MULTIPLEX FAMILIES IDENTIFIES RARE CODING VARIANTS IN KNOWN AND NOVEL ALZHEIMER’S DISEASE GENES by Cukier, Holly N, Kunkle, Brian W, Rolati, Sophie, Whitehead, Patrice L, Vance, Jeffery M, Cuccaro, Michael L, Carney, Regina M, Gilbert, John R, Martin, Eden R, Beecham, Gary W, Haines, Jonathan L, Pericak-Vance, Margaret A, Hamilton-Nelson, Kara L

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Whole-exome sequencing in early-onset Alzheimer disease cases identifies novel candidate genes by Beecham, Gary W, Kunkle, Brian W, Vardarajan, Badri, Whitehead, Patrice L, Rolati, Sophie, Martin, Eden R, Gilbert, John R, Mayeux, Richard, Haines, Jonathan L, Pericak-Vance, Margaret A

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IDENTIFICATION OF NOVEL CANDIDATE GENES FOR EARLY-ONSET ALZHEIMER'S DISEASE THROUGH INTEGRATED WHOLE-EXOME SEQUENCING AND EXOME CHIP ARRAY ASSOCIATION ANALYSIS by Kunkle, Brian W, Vardarajan, Badri N, Naj, Adam C, Cukier, Holly N, Dykxhoorn, Derek M, Rolati, Sophie, Whitehead, Patrice L, Carney, Regina M, Cuccaro, Michael L, Vance, Jeffery M, Genetics Consortium, Alzheimer's Disease, Farrer, Lindsay A, Haines, Jonathan L, Schellenberg, Gerard D, Martin, Eden R, Reitz, Christiane, Beecham, Gary W, Mayeux, Richard, Pericak-Vance, Margaret A

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P2‐013: ABCA7 deletion associated with Alzheimer's disease in african americans by Cukier, Holly N., Kunkle, Brian W., Rolati, Sophie, Hamilton-Nelson, Kara L., Kohli, Martin A., Dombroski, Beth A., Vardarajan, Badri N., Whitehead, Patrice L., Booven, Derek J., Martin, Eden R., Beecham, Gary W., Farrer, Lindsay A., Cuccaro, Michael L., Vance, Jeffery M., Mayeux, Richard, Gilbert, John R., Carney, Regina M., Byrd, Goldie S., Haines, Jonathan L., Schellenberg, Gerald D., Pericak-Vance, Margaret A., Lang, Rosalyn

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ABCA7 FRAMESHIFT DELETION ASSOCIATED WITH ALZHEIMER’S DISEASE IN AFRICAN AMERICANS by Dykxhoorn, Derek M, Cukier, Holly N, Kunkle, Brian W, Vardarajan, Badri N, Rolati, Sophie, Hamilton-Nelson, Kara L, Kohli, Martin A, Whitehead, Patrice L, Van Booven, Derek J, Lang, Rosalyn, Farrer, Lindsay A, Cuccaro, Michael L, Vance, Jeffery M, Gilbert, John R, Beecham, Gary W, Martin, Eden R, Carney, Regina M, Mayeux, Richard, Schellenberg, Gerard D, Byrd, Goldie S, Haines, Jonathan L, Pericak-Vance, Margaret A

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