Search Results - "Rok Krašovec"
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Electrical Impedance Spectroscopy with Bacterial Biofilms: Neuronal-like Behavior
Published in Nano letters (21-02-2024)“…Negative capacitance at low frequencies for spiking neurons was first demonstrated in 1941 (K. S. Cole) by using extracellular electrodes. The phenomenon…”
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Spontaneous mutation rate is a plastic trait associated with population density across domains of life
Published in PLoS biology (24-08-2017)“…Rates of random, spontaneous mutation can vary plastically, dependent upon the environment. Such plasticity affects evolutionary trajectories and may be…”
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Environmental and genetic influence on the rate and spectrum of spontaneous mutations in Escherichia coli
Published in Microbiology (Society for General Microbiology) (01-04-2024)“…Spontaneous mutations are the ultimate source of novel genetic variation on which evolution operates. Although mutation rate is often discussed as a single…”
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Collective peroxide detoxification determines microbial mutation rate plasticity in E. coli
Published in PLoS biology (15-07-2024)“…Mutagenesis is responsive to many environmental factors. Evolution therefore depends on the environment not only for selection but also in determining the…”
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Environmental pleiotropy and demographic history direct adaptation under antibiotic selection
Published in Heredity (01-11-2018)“…Evolutionary rescue following environmental change requires mutations permitting population growth in the new environment. If change is severe enough to…”
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Opposing effects of final population density and stress on Escherichia coli mutation rate
Published in The ISME Journal (01-12-2018)“…Evolution depends on mutations. For an individual genotype, the rate at which mutations arise is known to increase with various stressors (stress-induced…”
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Critical Mutation Rate has an Exponential Dependence on Population Size for Eukaryotic-length Genomes with Crossover
Published in Scientific reports (14-11-2017)“…The critical mutation rate (CMR) determines the shift between survival-of-the-fittest and survival of individuals with greater mutational robustness…”
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Measuring Microbial Mutation Rates with the Fluctuation Assay
Published in Journal of visualized experiments (28-11-2019)“…Fluctuation assays are widely used for estimating mutation rates in microbes growing in liquid environments. Many cultures are each inoculated with a few…”
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Mutation rate plasticity in rifampicin resistance depends on Escherichia coli cell–cell interactions
Published in Nature communications (29-04-2014)“…Variation of mutation rate at a particular site in a particular genotype, in other words mutation rate plasticity (MRP), can be caused by stress or ageing…”
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Electrical signaling in three-dimensional bacterial biofilms using an agent-based fire-diffuse-fire model
Published in Physical review. E (01-05-2024)“…Agent-based models were used to describe electrical signaling in bacterial biofilms in three dimensions. Specifically, wavefronts of potassium ions in…”
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Growth-dependent and adaptive mutation rates to ebgR and IS30 transposition in the bacteria Escherichia coli K-12 at different extracellular Mg2+ concentrations
Published in Acta Biologica Slovenica (01-07-2010)“…During starvation on carbon and energy Escherichia coli K-12 cells, modified to possess EbgA51 as the only く-galactosidase enzyme, experience adaptive…”
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On the origin of cancer: Can we ignore coherence?
Published in Progress in biophysics and molecular biology (01-08-2011)“…A growing number of inconsistencies have accumulated within the genetically deterministic paradigm of the origin of cancer. Among them the most important are…”
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Monotonicity of fitness landscapes and mutation rate control
Published in Journal of mathematical biology (01-12-2016)“…A common view in evolutionary biology is that mutation rates are minimised. However, studies in combinatorial optimisation and search have shown a clear…”
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14
Metabolic plasticity and the energy economizing effect of ibogaine, the principal alkaloid of Tabernanthe iboga
Published in Journal of ethnopharmacology (30-08-2012)“…The root bark of iboga plant—Tabernanthe iboga has been used traditionally in Central Africa as a psychoactive substance in religious rituals, while in smaller…”
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Possible time-dependent effect of ions and hydrophilic surfaces on the electrical conductivity of aqueous solutions
Published in International journal of molecular sciences (01-04-2012)“…The purpose of this work was to determine the influence of mechanical and electrical treatment on the electrical conductivity of aqueous solutions. Solutions…”
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Adaptive mutation: shall we survive bacterial genetic skills?
Published in Acta Biologica Slovenica (01-12-2002)“…The origin and dynamics of genetic variations is one of the key questions in the modem science that has still not come out with a final answer. Emerging…”
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Where antibiotic resistance mutations meet quorum-sensing
Published in Microbial cell (25-06-2014)“…We do not need to rehearse the grim story of the global rise of antibiotic resistant microbes. But what if it were possible to control the rate with which…”
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18
Deep Significance of the Field Concept in Contemporary Biomedical Sciences
Published in Electromagnetic biology and medicine (2009)“…Since antiquity, biology has had two opposing views of life and organisms: holistic (organismic) and reductionist. In contemporary biology, the molecular…”
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Electrical Transfer of Molecule Information into Water, Its Storage, and Bioeffects on Plants and Bacteria
Published in Electromagnetic biology and medicine (2005)“…The controversial phenomenon of the so-called water memory recently has been gaining in scientific credibility, either through direct empirical findings or…”
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Monotonicity of Fitness Landscapes and Mutation Rate Control
Published 24-08-2019“…J. Math. Biol. (2016) 73: 1491 A common view in evolutionary biology is that mutation rates are minimised. However, studies in combinatorial optimisation and…”
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