Search Results - "Rojas, Anabel"
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GATA4 and GATA6 control mouse pancreas organogenesis
Published in The Journal of clinical investigation (01-10-2012)“…Recently, heterozygous mutations in GATA6 have been found in neonatal diabetic patients with failed pancreatic organogenesis. To investigate the roles of GATA4…”
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2
Editorial: Look who's talking: Dialogues with beta cells
Published in Frontiers in endocrinology (Lausanne) (05-01-2023)Get full text
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The Wilms' tumor suppressor gene regulates pancreas homeostasis and repair
Published in PLoS genetics (14-02-2019)“…The Wilms' tumor suppressor gene (Wt1) encodes a zinc finger transcription factor that plays an essential role in the development of kidneys, gonads, spleen,…”
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Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio–venous connections
Published in Proceedings of the National Academy of Sciences - PNAS (19-01-2016)“…Recent reports suggest that mammalian embryonic coronary endothelium (CoE) originates from the sinus venosus and ventricular endocardium. However, the…”
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Conditional deletion of WT1 in the septum transversum mesenchyme causes congenital diaphragmatic hernia in mice
Published in eLife (19-09-2016)“…Congenital diaphragmatic hernia (CDH) is a severe birth defect. Wt1-null mouse embryos develop CDH but the mechanisms regulated by WT1 are unknown. We have…”
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Role of the Wilms' tumor suppressor gene Wt1 in pancreatic development
Published in Developmental dynamics (01-07-2018)“…The Wilms tumor suppressor gene (Wt1) encodes a transcription factor involved in the development of a number of organs, but the role played by Wt1 in…”
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Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr−/−.Leiden mice without attenuation of steatohepatitis
Published in Scientific reports (15-04-2021)“…Dietary fatty acids play a role in the pathogenesis of obesity-associated non-alcoholic fatty liver disease (NAFLD), which is associated with insulin…”
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GATA4 Is a Direct Transcriptional Activator of Cyclin D2 and Cdk4 and Is Required for Cardiomyocyte Proliferation in Anterior Heart Field-Derived Myocardium
Published in Molecular and Cellular Biology (01-09-2008)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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GATA4 loss in the septum transversum mesenchyme promotes liver fibrosis in mice
Published in Hepatology (Baltimore, Md.) (01-06-2014)“…The zinc finger transcription factor GATA4 controls specification and differentiation of multiple cell types during embryonic development. In mouse embryonic…”
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10
GATA4 induces liver fibrosis regression by deactivating hepatic stellate cells
Published in JCI insight (08-12-2021)“…In response to liver injury, hepatic stellate cells activate and acquire proliferative and contractile features. The regression of liver fibrosis appears to…”
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A population of hematopoietic stem cells derives from GATA4-expressing progenitors located in the placenta and lateral mesoderm of mice
Published in Haematologica (Roma) (01-04-2017)“…GATA transcription factors are expressed in the mesoderm and endoderm during development. GATA1-3, but not GATA4, are critically involved in hematopoiesis. An…”
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Loss of Pancreas upon Activated Wnt Signaling Is Concomitant with Emergence of Gastrointestinal Identity
Published in PloS one (13-10-2016)“…Organ formation is achieved through the complex interplay between signaling pathways and transcriptional cascades. The canonical Wnt signaling pathway plays…”
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Immunohistochemical assessment of Pax8 expression during pancreatic islet development and in human neuroendocrine tumors
Published in Histochemistry and cell biology (01-11-2011)“…The paired box transcription factor Pax8 is critical for development of the eye, thyroid gland as well as the urinary and reproductive organs. In adult, Pax8…”
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Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer
Published in Developmental biology (15-10-2010)“…The embryonic endoderm is a multipotent progenitor cell population that gives rise to the epithelia of the digestive and respiratory tracts, the liver and the…”
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Gata4 expression in lateral mesoderm is downstream of BMP4 and is activated directly by Forkhead and GATA transcription factors through a distal enhancer element
Published in Development (Cambridge) (01-08-2005)“…The GATA family of zinc-finger transcription factors plays key roles in the specification and differentiation of multiple cell types during development. GATA4…”
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NR5A2/LRH-1 regulates the PTGS2-PGE2-PTGER1 pathway contributing to pancreatic islet survival and function
Published in iScience (20-05-2022)“…LRH-1/NR5A2 is implicated in islet morphogenesis postnatally, and its activation using the agonist BL001 protects islets against apoptosis, reverting…”
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The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye
Published in Disease models & mechanisms (01-02-2015)“…Embryopathies that develop as a consequence of maternal diabetes have been studied intensely in both experimental and clinical scenarios. Accordingly,…”
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Determinants of Myogenic Specificity within MyoD Are Required for Noncanonical E Box Binding
Published in Molecular and Cellular Biology (01-08-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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"If we're here, it's only because we have no money…" discrimination and violence in Mexican maternity wards
Published in BMC pregnancy and childbirth (18-06-2018)“…Structural and gender violence in Mexico take on various forms, obstetric violence among them. The objective of our study consisted in analyzing experiences of…”
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An endoderm‐specific transcriptional enhancer from the mouse Gata4 gene requires GATA and homeodomain protein–binding sites for function in vivo
Published in Developmental dynamics (01-10-2009)“…Several transcription factors function in the specification and differentiation of the endoderm, including the zinc finger transcription factor GATA4. Despite…”
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