Search Results - "Roitman, Jamie"

Monotonic coding of numerosity in macaque lateral intraparietal area by Roitman, Jamie D, Brannon, Elizabeth M, Platt, Michael L

“…As any child knows, the first step in counting is summing up individual elements, yet the brain mechanisms responsible for this process remain obscure. Here we…”
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Ghrelin regulates phasic dopamine and nucleus accumbens signaling evoked by food‐predictive stimuli by Cone, Jackson J., Roitman, Jamie D., Roitman, Mitchell F.

“…Environmental stimuli that signal food availability hold powerful sway over motivated behavior and promote feeding, in part, by activating the mesolimbic…”
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Chronic water restriction reduces sensitivity to brain stimulation reward in male and female rats by Donka, Rachel M, Hsu, Ted, Roitman, Mitchell F, Roitman, Jamie D

“…•Acute water deprivation did not alter sensitivity to brain stimulation reward (BSR).•Chemogenetic activation of glutamatergic neurons in SFO also did not…”
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Thirst recruits phasic dopamine signaling through subfornical organ neurons by Hsu, Ted M., Bazzino, Paula, Hurh, Samantha J., Konanur, Vaibhav R., Roitman, Jamie D., Roitman, Mitchell F.

“…Thirst is a highly potent drive that motivates organisms to seek out and consume balance-restoring stimuli. The detection of dehydration is well understood and…”
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Effects of chronic cannabinoid exposure during adolescence on reward preference and mPFC activation in adulthood by Jacobs-Brichford, Eliza, Manson, Kirk F., Roitman, Jamie D.

“…Cannabis is one of the most commonly used drugs among adolescents, with initial use beginning between the ages of 12 to 17. Although often perceived as a ‘soft…”
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Response of Neurons in the Lateral Intraparietal Area during a Combined Visual Discrimination Reaction Time Task by Roitman, Jamie D, Shadlen, Michael N

“…Decisions about the visual world can take time to form, especially when information is unreliable. We studied the neural correlate of gradual decision…”
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Probabilistic Population Codes for Bayesian Decision Making by Beck, Jeffrey M., Ma, Wei Ji, Kiani, Roozbeh, Hanks, Tim, Churchland, Anne K., Roitman, Jamie, Shadlen, Michael N., Latham, Peter E., Pouget, Alexandre

“…When making a decision, one must first accumulate evidence, often over time, and then select the appropriate action. Here, we present a neural model of…”
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Effects of voluntary alcohol intake on risk preference and behavioral flexibility during rat adolescence by McMurray, Matthew S, Amodeo, Leslie R, Roitman, Jamie D

“…Alcohol use is common in adolescence, with a large portion of intake occurring during episodes of binging. This pattern of alcohol consumption coincides with a…”
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Linking neuroscience with modern concepts of impulse control disorders in Parkinson's disease by Napier, T. Celeste, Corvol, Jean-Christophe, Grace, Anthony A., Roitman, Jamie D., Rowe, James, Voon, Valerie, Strafella, Antonio P.

“…Patients with Parkinson's disease (PD) may experience impulse control disorders (ICDs) when on dopamine agonist therapy for their motor symptoms. In the last…”
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Nucleus accumbens responses differentiate execution and restraint in reward-directed behavior by Roitman, Jamie D, Loriaux, Amy L

“…Our behavior is powerfully driven by environmental cues that signal the availability of rewarding stimuli. We frequently encounter stimuli-a bowl of candy or…”
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Risk-preference differentiates orbitofrontal cortex responses to freely chosen reward outcomes by Roitman, Jamie D., Roitman, Mitchell F.

“…To successfully evaluate potential courses of action and choose the most favorable, we must consider the outcomes that may result. Many choices involve risk,…”
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A Role for Neural Integrators in Perceptual Decision Making by Mazurek, Mark E., Roitman, Jamie D., Ditterich, Jochen, Shadlen, Michael N.

“…Decisions based on uncertain information may benefit from an accumulation of information over time. We asked whether such an accumulation process may underlie…”
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One-Dimensional Dynamics of Attention and Decision Making in LIP by Ganguli, Surya, Bisley, James W., Roitman, Jamie D., Shadlen, Michael N., Goldberg, Michael E., Miller, Kenneth D.

“…Where we allocate our visual spatial attention depends upon a continual competition between internally generated goals and external distractions. Recently it…”
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Olanzapine, but Not Fluoxetine, Treatment Increases Survival in Activity-Based Anorexia in Mice by J KLENOTICH, Stephanie, P SEIGLIE, Mariel, S MCMURRAY, Matthew, D ROITMAN, Jamie, LE GRANGE, Daniel, DUGAD, Priya, C DULAWA, Stephanie

“…Anorexia nervosa (AN) is an eating disorder characterized by extreme hypophagia, hyperactivity, and fear of weight gain. No approved pharmacological treatments…”
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Acute and long-term effects of adolescent methylphenidate on decision-making and dopamine receptor mRNA expression in the orbitofrontal cortex by Amodeo, Leslie R., Jacobs-Brichford, Eliza, McMurray, Matthew S., Roitman, Jamie D.

“…•Adolescent methylphenidate (MPH) impaired reward size discrimination.•Delay discounting in adolescence was not affected by MPH.•In adulthood, adolescent MPH…”
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Nucleus accumbens shell, but not core, tracks motivational value of salt by Loriaux, Amy L, Roitman, Jamie D, Roitman, Mitchell F

“…To appropriately respond to an affective stimulus, we must be able to track its value across changes in both the external and internal environment. The nucleus…”
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Hedonic and Nucleus Accumbens Neural Responses to a Natural Reward Are Regulated by Aversive Conditioning by Roitman, Mitchell F, Wheeler, Robert A, Tiesinga, Paul H. E, Roitman, Jamie D, Carelli, Regina M

“…The nucleus accumbens (NAc) plays a role in hedonic reactivity to taste stimuli. Learning can alter the hedonic valence of a given stimulus, and it remains…”
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Representation of numerosity in posterior parietal cortex by Roitman, Jamie D, Brannon, Elizabeth M, Platt, Michael L

“…Humans and animals appear to share a similar representation of number as an analog magnitude on an internal, subjective scale. Neurological and…”
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Brain Stimulation Reward Supports More Consistent and Accurate Rodent Decision-Making than Food Reward by McMurray, Matthew S, Conway, Sineadh M, Roitman, Jamie D

“…Animal models of decision-making rely on an animal's motivation to decide and its ability to detect differences among various alternatives. Food reinforcement,…”
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Nonverbal representation of time and number in adults by Roitman, Jamie D., Brannon, Elizabeth M., Andrews, Jessica R., Platt, Michael L.

“…A wealth of human and animal research supports common neural processing of numerical and temporal information. Here we test whether adult humans spontaneously…”
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