Search Results - "Rohrer, Jacqueline"

Effects of Aromatase Inhibition in Elderly Men with Low or Borderline-Low Serum Testosterone Levels by Leder, Benjamin Z., Rohrer, Jacqueline L., Rubin, Stephen D., Gallo, Jose, Longcope, Christopher

“…As men age, serum testosterone levels decrease, a factor that may contribute to some aspects of age-related physiological deterioration. Although androgen…”
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Inhibition of the PI3K-Akt Signaling Pathway Reduces Tumor Necrosis Factor-α Production in Response to Titanium Particles in Vitro by Smith, Matthew V., Lee, Michael J., Islam, Andrew S., Rohrer, Jacqueline L., Goldberg, Victor M., Beidelschies, Michelle A., Greenfield, Edward M.

“…Background: Wear debris contributes to implant loosening after total joint arthroplasty, and few advances have been made in our ability to inhibit the…”
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Effect of aromatase inhibition on lipids and inflammatory markers of cardiovascular disease in elderly men with low testosterone levels by Dougherty, Ryan H., Rohrer, Jacqueline L., Hayden, Douglas, Rubin, Stephen D., Leder, Benjamin Z.

“…Summary Objective  Although androgen replacement has been shown to have beneficial effects in hypogonadal men, there is concern that androgens may…”
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The JAVA Based Computational Tool for Pairwise Comparison of Protein Backbone Folds in Liganded and Apo 3D Structures of the alpha/beta Hydrolase Fold Proteins by Zheng, Zihan, Rohrer, Jacqueline, RADIC, ZORAN

“…Cholinesterases, carboxylesterases and lipases are some of prominent catalytically active proteins with specifically similar, globular tertiary structure fold…”
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Interactive 3D Graphs Alongside Atomic Resolution Macromolecular Structures in the VR Space by Tran, Alexandria, Zheng, Zihan, Rohrer, Jacqueline, Martins, Sandra, RADIC, ZORAN

“…Virtual reality (VR) viewing of experimentally determined macromolecular 3D structures, at the atomic level resolution, represents closest to reality and most…”
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Covalent inhibition of hAChE by organophosphates causes homodimer dissociation through long-range allosteric effects by Blumenthal, Donald K., Cheng, Xiaolin, Fajer, Mikolai, Ho, Kwok-Yiu, Rohrer, Jacqueline, Gerlits, Oksana, Taylor, Palmer, Juneja, Puneet, Kovalevsky, Andrey, Radić, Zoran

“…Acetylcholinesterase (EC 3.1.1.7), a key acetylcholine-hydrolyzing enzyme in cholinergic neurotransmission, is present in a variety of states in situ,…”
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OVERLAY INDEPENDENT COMPARISON OF ACETYLCHOLINESTERASE 3D STRUCTURES REVEALS LIGAND SPECIFIC BACKBONE CHANGES UPON REVERSIBLE AND COVALENT BINDING by RADIC, ZORAN, Rohrer, Jacqueline, Sidhom, Morgana, Han, Jingting

“…Abstract only We developed a simple overlay independent comparison of protein 3D structure alpha carbon backbones and applied it to PDB deposited structures of…”
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Overlay-independent comparisons of X-ray structures reveal small, systematic conformational changes in liganded acetylcholinesterase by Rohrer, Jacqueline, Sidhom, Morgana, Han, Jingting, Radić, Zoran

“…Background and Purpose: Comparisons of macromolecular 3D structures by minimizing corresponding atom RMSDs can by virtue of averaging, hide small unexpected…”
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1070-103 Effect of aromatase inhibition on lipids and inflammatory markers of cardiovascular disease in elderly hypogonadal men: A double-blind placebo-controlled randomized trial by Dougherty, Ryan, Rohrer, Jacqueline L, Hayden, Douglas, Leder, Benjamin Z

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Inhibition of the PI3K-Akt Signaling Pathway Reduces Tumor Necrosis Factor-? Production in Response to Titanium Particles in Vitro by Smith, Matthew V., Lee, Michael J., Islam, Andrew S., Rohrer, Jacqueline L., Goldberg, Victor M., Beidelschies, Michelle A., Greenfield, Edward M.

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Inhibition of the PI3K-Akt Signaling Pathway Reduces Tumor Necrosis Factor-α Production in Response to Titanium Particles in Vitro by Smith, Matthew V., MD, Lee, Michael J., MD, Islam, Andrew S., MD, Goldberg, Victor M., MD, Rohrer, Jacqueline L., BS, Beidelschies, Michelle A., BS, Greenfield, Edward M., PhD

“…Background Wear debris contributes to implant loosening after total joint arthroplasty, and few advances have been made in our ability to inhibit the…”
Get full text