Search Results - "Rohr, Klaus B"

The Living with Pulmonary Fibrosis questionnaire in progressive fibrosing interstitial lung disease by Swigris, Jeffrey, Cutts, Katelyn, Male, Natalia, Baldwin, Michael, Rohr, Klaus B., Bushnell, Donald M.

“…The Living with Idiopathic Pulmonary Fibrosis (L-IPF) questionnaire was developed with substantial input from patients with idiopathic pulmonary fibrosis (IPF)…”
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Analysis of origin and growth of the thyroid gland in zebrafish by Alt, Burkhard, Reibe, Saskia, Feitosa, Natalia M., Elsalini, Osama A., Wendl, Thomas, Rohr, Klaus B.

“…The zebrafish thyroid gland shows a unique pattern of growth as a differentiated endocrine gland. Here, we analyze the onset of differentiation, the…”
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Pituitary-Interrenal Interaction in Zebrafish Interrenal Organ Development by To, Thuy Thanh, Hahner, Stefanie, Nica, Gabriela, Rohr, Klaus B, Hammerschmidt, Matthias, Winkler, Christoph, Allolio, Bruno

“…To further elucidate pituitary adrenal interactions during development, we studied the organogenesis of the interrenal organ, the teleost homolog of the…”
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Phase 3 Trial of BI 695502 Plus Chemotherapy Versus Bevacizumab Reference Product Plus Chemotherapy in Patients With Advanced Nonsquamous NSCLC by Kim, Edward S., Balser, Sigrid, Rohr, Klaus B., Lohmann, Ragna, Liedert, Bernd, Schliephake, Dorothee

“…Biological therapies such as bevacizumab have improved survival in patients with NSCLC. This study was conducted to confirm the equivalent efficacy of the…”
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Developing a conceptual model of symptoms and impacts in progressive fibrosing interstitial lung disease to evaluate patient-reported outcome measures by Wijsenbeek, Marlies, Molina-Molina, Maria, Chassany, Olivier, Fox, John, Galvin, Liam, Geissler, Klaus, Hammitt, Katherine M, Kreuter, Michael, Moua, Teng, O'Brien, Emily C, Slagle, Ashley F, Krasnow, Anna, Reaney, Matthew, Baldwin, Michael, Male, Natalia, Rohr, Klaus B, Swigris, Jeff, Antoniou, Katerina

“…An understanding of the experience of patients with progressive fibrosing interstitial lung disease (PF-ILD) is needed to select appropriate patient-reported…”
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Early developmental specification of the thyroid gland depends on han-expressing surrounding tissue and on FGF signals by Wendl, Thomas, Adzic, Dejan, Schoenebeck, Jeffrey J, Scholpp, Steffen, Brand, Michael, Yelon, Deborah, Rohr, Klaus B

“…The thyroid is an endocrine gland in all vertebrates that develops from the ventral floor of the anterior pharyngeal endoderm. Unravelling the molecular…”
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Arteries define the position of the thyroid gland during its developmental relocalisation by Alt, Burkhard, Elsalini, Osama A., Schrumpf, Pamela, Haufs, Nele, Lawson, Nathan D., Schwabe, Georg C., Mundlos, Stefan, Grüters, Annette, Krude, Heiko, Rohr, Klaus B.

“…During vertebrate development, the thyroid gland undergoes a unique relocalisation from its site of induction to a distant species-specific position in the…”
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pax2.1 is required for the development of thyroid follicles in zebrafish by Wendl, Thomas, Lun, Klaus, Mione, Marina, Favor, Jack, Brand, Michael, Wilson, Stephen W, Rohr, Klaus B

“…The thyroid gland is an organ primarily composed of endoderm-derived follicular cells. Although disturbed embryonic development of the thyroid gland leads to…”
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Phenylthiourea disrupts thyroid function in developing zebrafish by Elsalini, Osama A, Rohr, Klaus B

“…Thyroid hormone (T4) can be detected in thyroid follicles in wild-type zebrafish larvae from 3 days of development, when the thyroid has differentiated. In…”
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Anterior and posterior waves of cyclic her1 gene expression are differentially regulated in the presomitic mesoderm of zebrafish by Gajewski, Martin, Sieger, Dirk, Alt, Burkhard, Leve, Christian, Hans, Stefan, Wolff, Christian, Rohr, Klaus B, Tautz, Diethard

“…Somite formation in vertebrates depends on a molecular oscillator in the presomitic mesoderm (PSM). In order to get a better insight into how oscillatory…”
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The psychometric properties of the King's Brief Interstitial Lung Disease questionnaire and thresholds for meaningful treatment response in patients with progressive fibrosing interstitial lung diseases by Birring, Surinder S, Bushnell, Donald M, Baldwin, Michael, Mueller, Heiko, Male, Natalia, Rohr, Klaus B, Inoue, Yoshikazu

“…There is a lack of fully validated patient-reported outcome measures for progressive fibrosing interstitial lung disease (ILD). We aimed to validate the King's…”
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Home spirometry in patients with idiopathic pulmonary fibrosis: data from the INMARK trial by Noth, Imre, Cottin, Vincent, Chaudhuri, Nazia, Corte, Tamera J, Johannson, Kerri A, Wijsenbeek, Marlies, Jouneau, Stephane, Michael, Andreas, Quaresma, Manuel, Rohr, Klaus B, Russell, Anne-Marie, Stowasser, Susanne, Maher, Toby M

“…Data from the INMARK trial were used to investigate the feasibility and validity of home spirometry as a measure of lung function decline in patients with…”
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Meta-Analysis of Effect of Nintedanib on Reducing FVC Decline Across Interstitial Lung Diseases by Bonella, Francesco, Cottin, Vincent, Valenzuela, Claudia, Wijsenbeek, Marlies, Voss, Florian, Rohr, Klaus B., Stowasser, Susanne, Maher, Toby M.

“…Introduction The effect of nintedanib on slowing the rate of decline in forced vital capacity (FVC) has been investigated in randomized placebo-controlled…”
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Using Data on Survival with Idiopathic Pulmonary Fibrosis to Estimate Survival with Other Types of Progressive Fibrosis Interstitial Lung Disease: A Bayesian Framework by Langford, Bryony, Diamantopoulos, Alex, Maher, Toby M., Inoue, Yoshikazu, Rohr, Klaus B., Baldwin, Michael

“…Introduction Among the various types of progressive fibrosing interstitial lung diseases (PF-ILDs), substantial survival data exist for idiopathic pulmonary…”
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fgf1 is required for normal differentiation of erythrocytes in zebrafish primitive hematopoiesis by Songhet, Pascal, Adzic, Dejan, Reibe, Saskia, Rohr, Klaus B.

“…Hematopoiesis in vertebrate development involves an embryonic, primitive wave and a later, definitive wave in which embryonic blood cells are replaced with…”
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The effect of nintedanib on health-related quality of life in Japanese patients with progressive fibrosing interstitial lung diseases: A subset analysis of the INBUILD trial by Inoue, Yoshikazu, Kitamura, Hideya, Okamoto, Masaki, Ogura, Takashi, Nishioka, Yasuhiko, Kuwana, Masataka, Taniguchi, Atsushi, Ito, Tomohiro, Rohr, Klaus B., Suda, Takafumi

“…In previous Japanese subgroup/subset analyses of the global INBUILD trial, nintedanib reduced the annual rate of forced vital capacity (FVC) decline and the…”
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Nintedanib in Asian patients with progressive fibrosing interstitial lung diseases: Results from the INBUILD trial by Inoue, Yoshikazu, Wells, Athol U., Song, Jin Woo, Xu, Zuojun, Kitamura, Hideya, Suda, Takafumi, Okamoto, Masaki, Müller, Heiko, Coeck, Carl, Rohr, Klaus B., Kolb, Martin, Brown, Kevin K.

“…Background and Objective In the INBUILD trial in patients with progressive fibrosing interstitial lung diseases (ILDs), nintedanib reduced the rate of decline…”
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Effects of nintedanib on disease progression and safety in Japanese patients with progressive fibrosing interstitial lung diseases: Further subset analysis from the whole INBUILD trial by Ogura, Takashi, Suda, Takafumi, Inase, Naohiko, Nishioka, Yasuhiko, Azuma, Arata, Okamoto, Masaki, Takizawa, Ayako, Ito, Tomohiro, Rohr, Klaus B., Inoue, Yoshikazu

“…A previous subgroup analysis of data from the INBUILD trial showed that nintedanib reduced the annual rate of decline in forced vital capacity (FVC) in…”
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Zebrafish hhex, nk2.1a, and pax2.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors by Elsalini, Osama A, Gartzen, Julia von, Cramer, Matthias, Rohr, Klaus B

“…During zebrafish development, the thyroid primordium initiates expression of molecular markers such as hhex and nk2.1a in the endoderm prior to pharynx…”
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The Nodal Pathway Acts Upstream of Hedgehog Signaling to Specify Ventral Telencephalic Identity by Rohr, Klaus B., Barth, K.Anukampa, Varga, Zoltán M., Wilson, Stephen W.

“…The Nodal and Hedgehog signaling pathways influence dorsoventral patterning at all axial levels of the CNS, but it remains largely unclear how these pathways…”
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