Search Results - "Rohner, Iris"

SAMD1 suppresses epithelial-mesenchymal transition pathways in pancreatic ductal adenocarcinoma by Simon, Clara, Brunke, Inka D, Stielow, Bastian, Forné, Ignasi, Steitz, Anna Mary, Geller, Merle, Rohner, Iris, Weber, Lisa Marie, Fischer, Sabrina, Jeude, Lea Marie, Huber, Theresa, Nist, Andrea, Stiewe, Thorsten, Huber, Magdalena, Buchholz, Malte, Liefke, Robert

“…Pancreatic ductal adenocarcinoma (PDAC) poses a significant threat due to its tendency to evade early detection, frequent metastasis, and the subsequent…”
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The CpG Island-Binding Protein SAMD1 Contributes to an Unfavorable Gene Signature in HepG2 Hepatocellular Carcinoma Cells by Simon, Clara, Stielow, Bastian, Nist, Andrea, Rohner, Iris, Weber, Lisa Marie, Geller, Merle, Fischer, Sabrina, Stiewe, Thorsten, Liefke, Robert

“…The unmethylated CpG island-binding protein SAMD1 is upregulated in many human cancer types, but its cancer-related role has not yet been investigated. Here,…”
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Complex phenotype of mice homozygous for a null mutation in the Sp4 transcription factor gene by Göllner, Heike, Bouwman, Peter, Mangold, Monika, Karis, Alar, Braun, Harald, Rohner, Iris, Del Rey, Adriana, Besedovsky, Hugo‐Oskar, Meinhardt, Andreas, Van Den Broek, Marion, Cutforth, Tyler, Grosveld, Frank, Philipsen, Sjaak, Suske, Guntram

“…Background Sp4 is a zinc finger transcription factor which is closely related to Sp1 and Sp3. All three proteins recognize the same DNA elements and can act as…”
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The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain by Weber, Lisa Marie, Jia, Yulin, Stielow, Bastian, Gisselbrecht, Stephen S, Cao, Yinghua, Ren, Yanpeng, Rohner, Iris, King, Jessica, Rothman, Elisabeth, Fischer, Sabrina, Simon, Clara, Forné, Ignasi, Nist, Andrea, Stiewe, Thorsten, Bulyk, Martha L, Wang, Zhanxin, Liefke, Robert

“…The lysine acetyltransferase KAT6A (MOZ, MYST3) belongs to the MYST family of chromatin regulators, facilitating histone acetylation. Dysregulation of KAT6A…”
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The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands by Stielow, Bastian, Zhou, Yuqiao, Cao, Yinghua, Simon, Clara, Pogoda, Hans-Martin, Jiang, Junyi, Ren, Yanpeng, Phanor, Sabrina Keita, Rohner, Iris, Nist, Andrea, Stiewe, Thorsten, Hammerschmidt, Matthias, Shi, Yang, Bulyk, Martha L, Wang, Zhanxin, Liefke, Robert

“…CpG islands (CGIs) are key regulatory DNA elements at most promoters, but how they influence the chromatin status and transcription remains elusive. Here, we…”
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Synthesis and secretion of the anticoagulant protein S and coexpression of the Tyro3 receptor in human lung carcinoma cells by Wimmel, Anja, Rohner, Iris, Ramaswamy, Annette, Heidtmann, Hans‐H., Seitz, Rainer, Kraus, Michael, Schuermann, Marcus

“…BACKGROUND Protein S is a plasma protein that serves as an important cofactor for activated protein C in the blood anticoagulation system. Protein S also acts…”
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Thrombomodulin and ristocetincofactor in homocystinuria: A study in two siblings by Schienle, Hans Wolfgang, Seitz, Rainer, Nawroth, Peter, Rohner, Iris, Lerch, Lydia, Krumpholz, Barbara, Krauß, Gertrud, Fowler, Brian, Baumgartner, Regula, Willenbockel, Ulrich, Egbring, Rudolf

“…Homocystinuria due to cystathionine-β-synthase deficiency (CBS-def-HOCY) initially often presents with vascular disorders, e.g. thromboembolic events. The…”
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