Search Results - "Rohn, Susanne"

Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions by Kalus, Ina, Rohn, Susanne, Puvirajesinghe, Tania M, Guimond, Scott E, Eyckerman-Kölln, Pieter J, Ten Dam, Gerdy, van Kuppevelt, Toin H, Turnbull, Jeremy E, Dierks, Thomas

“…Sulf1 and Sulf2 are cell surface sulfatases, which remove specific 6-O-sulfate groups from heparan sulfate (HS) proteoglycans, resulting in modulation of…”
Get full text

FAD-mutation of APP is associated with a loss of its synaptotrophic activity by Seeger, Gudrun, Gärtner, Ulrich, Ueberham, Uwe, Rohn, Susanne, Arendt, Thomas

“…Abstract Alzheimer's disease (AD) is a chronic neurodegenerative disorder associated with extracellular accumulation of Aβ peptide that derives from the…”
Get full text

Functionalizable silica-based micron-sized iron oxide particles for cellular magnetic resonance imaging by Raschzok, Nathanael, Langer, Carolin M, Schmidt, Christian, Lerche, Karl H, Billecke, Nils, Nehls, Kerstin, Schlüter, Natalie B, Leder, Annekatrin, Rohn, Susanne, Mogl, Martina T, Lüdemann, Lutz, Stelter, Lars, Teichgräber, Ulf K, Neuhaus, Peter, Sauer, Igor M

“…Cellular therapies require methods for noninvasive visualization of transplanted cells. Micron-sized iron oxide particles (MPIOs) generate a strong contrast in…”
Get full text

3D-Bioreactor culture of human hepatoma cell line HepG2 as a promising tool for in vitro substance testing by Goepfert, Christiane, Scheurer, Wibke, Rohn, Susanne, Rathjen, Britta, Meyer, Stefanie, Dittmann, Anja, Wiegandt, Katharina, Janßen, Rolf, Pörtner, Ralf

Get full text

Improved rat liver decellularization by arterial perfusion under oscillating pressure conditions by Struecker, Benjamin, Butter, Antje, Hillebrandt, Karl, Polenz, Dietrich, Reutzel‐Selke, Anja, Tang, Peter, Lippert, Steffen, Leder, Anne, Rohn, Susanne, Geisel, Dominik, Denecke, Timm, Aliyev, Khalid, Jöhrens, Korinna, Raschzok, Nathanael, Neuhaus, Peter, Pratschke, Johann, Sauer, Igor M

“…One approach of regenerative medicine to generate functional hepatic tissue in vitro is decellularization and recellularization, and several protocols for the…”
Get full text

Microglia and astrocytes attenuate the replication of the oncolytic vaccinia virus LIVP 1.1.1 in murine GL261 gliomas by acting as vaccinia virus traps by Kober, Christina, Rohn, Susanne, Weibel, Stephanie, Geissinger, Ulrike, Chen, Nanhai G, Szalay, Aladar A

“…Oncolytic virotherapy is a novel approach for the treatment of glioblastoma multiforme (GBM) which is still a fatal disease. Pathologic features of GBM are…”
Get full text

Neuroprotection against iron-induced cell death by perineuronal nets - an in vivo analysis of oxidative stress by Suttkus, Anne, Rohn, Susanne, Jäger, Carsten, Arendt, Thomas, Morawski, Markus

“…Perineuronal nets (PNs) are a specialized form of extracellular matrix, surrounding different types of neurons and mainly consist of chondroitin sulfate…”
Get full text

RVG peptide as transfection reagent for specific cdk4 gene silencing in vitro and in vivo by Rohn, Susanne, Suttkus, Anne, Arendt, Thomas, Ueberham, Uwe

“…The rabies virus glycoprotein (RVG) peptide is known as a transfection reagent for systemic delivery of small interfering RNA (siRNA) into the brain. However,…”
Get full text

Isolation, Characterization and Cold Storage of Cells Isolated from Diseased Explanted Livers by Belaschk, Elisa, Rohn, Susanne, Mukiibi, Ramla, Reutzel-Selke, Anja, Tang, Peter, Sawitzki, Birgit, Pratschke, Johann, Sauer, Igor M., Mogl, Martina T.

“…Introduction Livers discarded after standard organ retrieval are commonly used as a cell source for hepatocyte transplantation. Due to the scarcity of organ…”
Get full text

Transcriptional control of cell cycle-dependent kinase 4 by Smad proteins—implications for Alzheimer's disease by Ueberham, Uwe, Hilbrich, Isabel, Ueberham, Elke, Rohn, Susanne, Glöckner, Pia, Dietrich, Katharina, Brückner, Martina K, Arendt, Thomas

“…Abstract Alzheimer's disease (AD) is a neurodegenerative disorder characterized by deregulation of neuronal cell cycle and differentiation control eventually…”
Get full text

Pin 1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in A lzheimer's disease by Ueberham, Uwe, Rohn, Susanne, Ueberham, Elke, Wodischeck, Susanne, Hilbrich, Isabel, Holzer, Max, Brückner, Martina K., Gruschka, Hildegard, Arendt, Thomas

“…Aims Neurodegeneration in A lzheimer's disease ( AD ) is characterized by pathological protein aggregates and inadequate activation of cell cycle regulating…”
Get full text

Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease by Ueberham, Uwe, Rohn, Susanne, Ueberham, Elke, Wodischeck, Susanne, Hilbrich, Isabel, Holzer, Max, Brückner, Martina K., Gruschka, Hildegard, Arendt, Thomas

“…Aims Neurodegeneration in Alzheimer's disease (AD) is characterized by pathological protein aggregates and inadequate activation of cell cycle regulating…”
Get full text

Improved rat liver decellularization by arterial perfusion under oscillating pressure conditions: Arterial rat liver decellularization by Struecker, Benjamin, Butter, Antje, Hillebrandt, Karl, Polenz, Dietrich, Reutzel-Selke, Anja, Tang, Peter, Lippert, Steffen, Leder, Anne, Rohn, Susanne, Geisel, Dominik, Denecke, Timm, Aliyev, Khalid, Jöhrens, Korinna, Raschzok, Nathanael, Neuhaus, Peter, Pratschke, Johann, Sauer, Igor M.

Get full text

Intratumoral INF-γ triggers an antiviral state in GL261 tumor cells: a major hurdle to overcome for oncolytic vaccinia virus therapy of cancer by Kober, Christina, Weibel, Stephanie, Rohn, Susanne, Kirscher, Lorenz, Szalay, Aladar A

“…Oncolytic vaccinia virus (VACV) therapy is an alternative treatment option for glioblastoma multiforme. Here, we used a comparison of different tumor locations…”
Get full text

An operational concept for long-term cinemicrography of cells in mono- and co-culture under highly controlled conditions – The SlideObserver by Billecke, Nils, Raschzok, Nathanael, Rohn, Susanne, Morgul, Mehmet H., Schwartlander, Ruth, Mogl, Martina, Wollersheim, Sonja, Schmitt, Katharina R., Sauer, Igor M.

“…► Parallel time-lapse recording of different sets of cells in culture is challenging. ► We developed the SlideObserver for long-term culture and…”
Get full text

Intratumoral INF-γ triggers an antiviral state in GL261 tumor cells: a major hurdle to overcome for oncolytic vaccinia virus therapy of cancer by Christina Kober, Stephanie Weibel, Susanne Rohn, Lorenz Kirscher, Aladar A Szalay

“…Oncolytic vaccinia virus (VACV) therapy is an alternative treatment option for glioblastoma multiforme. Here, we used a comparison of different tumor locations…”
Get full text

Smad2 isoforms are differentially expressed during mouse brain development and aging by Ueberham, Uwe, Lange, Peggy, Ueberham, Elke, Brückner, Martina K., Hartlage‐Rübsamen, Maike, Pannicke, Thomas, Rohn, Susanne, Cross, Michael, Arendt, Thomas

“…Smad2 and Smad3 are central molecules of the TGFβ and activin receptor complex mediated intracellular signaling pathway. They function as important…”
Get full text

Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting Functions: e0139853 by Kalus, Ina, Rohn, Susanne, Puvirajesinghe, Tania M, Guimond, Scott E, Eyckerman-Kolln, Pieter J, Dam, Gerdy ten, Kuppevelt, Toin Hvan, Turnbull, Jeremy E, Dierks, Thomas

“…Introduction Sulf1 and Sulf2 are cell surface sulfatases, which remove specific 6-O-sulfate groups from heparan sulfate (HS) proteoglycans, resulting in…”
Get full text

Activity-induced dendrite and dendritic spine development in human amyloid precursor protein transgenic mice by Alpár, Alán, Ueberham, Uwe, Lendvai, Dávid, Naumann, Nicole, Rohn, Susanne, Gáti, Georgina, Arendt, Thomas, Gärtner, Ulrich

“…► Overexpression of wild-type hAPP promotes dendritic growth but not dendritic spine establishment. ► Overexpression of wild-type hAPP potentiates dendritic…”
Get full text

3D-Bioreactor culture of human hepatoma cell line HepG2 as a promising tool for in vitrosubstance testing by Goepfert, Christiane, Scheurer, Wibke, Rohn, Susanne, Rathjen, Britta, Meyer, Stefanie, Dittmann, Anja, Wiegandt, Katharina, Janßen, Rolf, Pörtner, Ralf

Get full text