Search Results - "Rohleder, Cathrin"

Cannabidiol and Amisulpride Improve Cognition in Acute Schizophrenia in an Explorative, Double-Blind, Active-Controlled, Randomized Clinical Trial by Leweke, F Markus, Rohleder, Cathrin, Gerth, Christoph W, Hellmich, Martin, Pukrop, Ralf, Koethe, Dagmar

“…Cannabidiol (CBD), a principal phytocannabinoid constituent, has demonstrated antipsychotic properties in recent clinical trials. While it has also been…”
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Role of the Endocannabinoid System in the Pathophysiology of Schizophrenia: Implications for Pharmacological Intervention by Leweke, F. Markus, Mueller, Juliane K., Lange, Bettina, Fritze, Stefan, Topor, Cristina E., Koethe, Dagmar, Rohleder, Cathrin

“…The term schizophrenia describes a group of multifaceted psychiatric conditions causing significant impairment of the quality of life of affected patients…”
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Cannabidiol enhances cerebral glucose utilization and ameliorates psychopathology and cognition: A case report in a clinically high-risk mental state by Koethe, Dagmar, Rohleder, Cathrin, Kracht, Lutz, Leweke, F Markus

“…Adolescent individuals often present with subtle, sub-threshold psychiatric syndromes that fluctuate or persist for years. These symptoms have been classified…”
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Cannabidiol as a Potential New Type of an Antipsychotic. A Critical Review of the Evidence by Rohleder, Cathrin, Müller, Juliane K, Lange, Bettina, Leweke, F M

“…There is urgent need for the development of mechanistically different and less side-effect prone antipsychotic compounds. The endocannabinoid system has been…”
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Current State of Fluid Lipid Biomarkers for Personalized Diagnostics and Therapeutics in Schizophrenia Spectrum Disorders and Related Psychoses: A Narrative Review by Couttas, Timothy A., Jieu, Beverly, Rohleder, Cathrin, Leweke, F. Markus

“…Schizophrenia spectrum disorders (SSD) are traditionally diagnosed and categorized through clinical assessment, owing to their complex heterogeneity and an…”
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Case Report: Severe Adolescent Major Depressive Syndrome Turns Out to Be an Unusual Case of Anti-NMDA Receptor Encephalitis by Moldavski, Alexander, Wenz, Holger, Lange, Bettina E., Rohleder, Cathrin, Leweke, F. Markus

“…Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a neuroinflammatory condition mediated by autoantibodies against the GluN1 subunit of the receptor…”
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ReTimeML: a retention time predictor that supports the LC–MS/MS analysis of sphingolipids by Allwright, Michael, Guennewig, Boris, Hoffmann, Anna E., Rohleder, Cathrin, Jieu, Beverly, Chung, Long H., Jiang, Yingxin C., Lemos Wimmer, Bruno F., Qi, Yanfei, Don, Anthony S., Leweke, F. Markus, Couttas, Timothy A.

“…The analysis of ceramide (Cer) and sphingomyelin (SM) lipid species using liquid chromatography–tandem mass spectrometry (LC–MS/MS) continues to present…”
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Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Emotion, Cognition, and Attention: A Double-Blind, Placebo-Controlled, Randomized Experimental Trial in Healthy Volunteers by Woelfl, Timo, Rohleder, Cathrin, Mueller, Juliane K., Lange, Bettina, Reuter, Anne, Schmidt, Anna Maria, Koethe, Dagmar, Hellmich, Martin, Leweke, F. Markus

“…The two main phytocannabinoids—delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD)—have been extensively studied, and it has been shown that THC can…”
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Neural Autoantibodies in Cerebrospinal Fluid and Serum in Clinical High Risk for Psychosis, First-Episode Psychosis, and Healthy Volunteers by Bien, Christian G, Rohleder, Cathrin, Mueller, Juliane K, Bien, Corinna I, Koethe, Dagmar, Leweke, F Markus

“…The pathophysiological role of neural autoantibodies in acute psychotic disorders is receiving increased attention. However, there is still an ongoing debate,…”
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The Functional Networks of Prepulse Inhibition: Neuronal Connectivity Analysis Based on FDG-PET in Awake and Unrestrained Rats by Rohleder, Cathrin, Wiedermann, Dirk, Neumaier, Bernd, Drzezga, Alexander, Timmermann, Lars, Graf, Rudolf, Leweke, F Markus, Endepols, Heike

“…Prepulse inhibition (PPI) is a neuropsychological process during which a weak sensory stimulus ("prepulse") attenuates the motor response ("startle reaction")…”
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Oleoylethanolamide and human neural responses to food stimuli in obesity by Grosshans, Martin, Schwarz, Emanuel, Bumb, Jan Malte, Schaefer, Carola, Rohleder, Cathrin, Vollmert, Christian, Vollstädt-Klein, Sabine, Tost, Heike, Meyer-Lindenberg, Andreas, Kiefer, Falk, Leweke, F Markus

“…Obesity has emerged as a leading health threat but its biological basis remains insufficiently known, hampering the search for novel treatments. Here, we study…”
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IgG dynamics of dietary antigens point to cerebrospinal fluid barrier or flow dysfunction in first-episode schizophrenia by Severance, Emily G, Gressitt, Kristin L, Alaedini, Armin, Rohleder, Cathrin, Enning, Frank, Bumb, J. Malte, Müller, Juliane K, Schwarz, Emanuel, Yolken, Robert H, Leweke, F. Markus

“…Abstract Schizophrenia is a complex brain disorder that may be accompanied by idiopathic inflammation. Classic central nervous system (CNS) inflammatory…”
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Plasma endocannabinoids in cocaine dependence and their relation to cerebral metabotropic glutamate receptor 5 density by Kroll, Sara L., Hulka, Lea M., Kexel, Ann-Kathrin, Vonmoos, Matthias, Preller, Katrin H., Treyer, Valerie, Ametamey, Simon M., Baumgartner, Markus R., Boost, Carola, Pahlisch, Franziska, Rohleder, Cathrin, Leweke, F. Markus, Quednow, Boris B.

“…Animal models indicate that the endocannabinoid system (ECS) plays a modulatory role in stress and reward processing, both crucially impaired in addictive…”
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EMPOWERED trial: protocol for a randomised control trial of digitally supported, highly personalised and measurement-based care to improve functional outcomes in young people with mood disorders by Hickie, Ian B, Iorfino, Frank, Rohleder, Cathrin, Song, Yun Ju Christine, Nichles, Alissa, Zmicerevska, Natalia, Capon, William, Guastella, Adam J, Leweke, F Markus, Scott, Jan, McGorry, Patrick, Mihalopoulos, Cathrine, Killackey, Eoin, Chong, Min K, McKenna, Sarah, Aji, Melissa, Gorban, Carla, Crouse, Jacob J, Koethe, Dagmar, Battisti, Robert, Hamilton, Blake, Lo, Alice, Hackett, Maree L, Hermens, Daniel F, Scott, Elizabeth M, Yim, Mark, Whitwell, Bradley, Crowley, Alison, Fowler, Donna, Volanakis, Elana, Papageorgopoulos, Vicki, Russel, Matilda, Phung, Elizabeth

“…ObjectivesMany adolescents and young adults with emerging mood disorders do not achieve substantial improvements in education, employment, or social function…”
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Editorial: Immune Associated Mental Illnesses in Adolescents and Young Adults: Pathophysiological Role and Therapeutic Perspectives by Banati, Richard B, Rohleder, Cathrin, Leweke, F Markus, Mueller, Norbert, Sawa, Akira, Yolken, Robert H, Hickie, Ian B

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Effects of adjunctive brexpiprazole on sleep-wake and circadian parameters in youth with depressive disorders: study protocol for a clinical trial by Carpenter, Joanne S, Zmicerevska, Natalia, Crouse, Jacob J, Nichles, Alissa, Garland, Alexandra, Song, Yun Ju Christine, Wilson, Chloe, Rohleder, Cathrin, McHugh, Catherine, Leweke, F. Markus, Koethe, Dagmar, Scott, Elizabeth M, Hickie, Ian B

“…IntroductionSleep-wake and circadian disturbance is a key feature of mood disorders with a potential causal role and particular relevance to young people…”
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Protocol for a young adult mental health (Uspace) cohort: personalising multidimensional care in young people admitted to hospital by Tickell, Ashleigh M, Rohleder, Cathrin, Garland, Alexandra, Song, Yun Ju Christine, Carpenter, Joanne Sarah, Harel, Kate, Parker, Lisa, Hickie, Ian B, Scott, Elizabeth

“…IntroductionCurrently, the literature on personalised and measurement-based mental healthcare is inadequate with major gaps in the development and evaluation…”
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Neurobiology Youth Follow-up Study: protocol to establish a longitudinal and prospective research database using multimodal assessments for current and past mental health treatment-seeking young people within an early intervention service by Nichles, Alissa, Zmicerevska, Natalia, Song, Yun Ju Christine, Wilson, Chloe, McHugh, Catherine, Hamilton, Blake, Crouse, Jacob, Rohleder, Cathrin, Carpenter, Joanne Sarah, Ho, Nicholas, Hermens, Daniel F, Wray, Naomi, Scott, Jan, Merikangas, Kathleen R, Leweke, F Markus, Koethe, Dagmar, Iorfino, Frank, Naismith, Sharon L, Guastella, Adam J, Scott, Elizabeth M, Hickie, Ian B

“…IntroductionApproximately 75% of major mental illness occurs before the age of 25 years. Despite this, our capacity to provide effective, early and…”
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Dose-dependent effects of oral cannabidiol and delta-9-tetrahydrocannabinol on serum anandamide and related N-acylethanolamines in healthy volunteers by Couttas, Timothy A, Boost, Carola, Pahlisch, Franziska, Sykorova, Eliska B, Mueller, Juliane K, Jieu, Beverly, Leweke, Judith E, Dammann, Inga, Hoffmann, Anna E, Loeffler, Martin, Grimm, Oliver, Enning, Frank, Flor, Herta, Meyer-Lindenberg, Andreas, Koethe, Dagmar, Rohleder, Cathrin, Leweke, F Markus

“…BackgroundThe mental health benefits of cannabidiol (CBD) are promising but can be inconsistent, in part due to challenges in defining an individual’s…”
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Designing an App for Parents and Caregivers to Promote Cognitive and Socioemotional Development and Well-being Among Children Aged 0 to 5 Years in Diverse Cultural Settings: Scientific Framework by Crouse, Jacob J, LaMonica, Haley M, Song, Yun Ju Christine, Boulton, Kelsie A, Rohleder, Cathrin, DeMayo, Marilena M, Wilson, Chloe E, Loblay, Victoria, Hindmarsh, Gabrielle, Stratigos, Tina, Krausz, Michael, Foo, Nathanael, Teo, Melissa, Hunter, Andrew, Guastella, Adam J, Banati, Richard B, Troy, Jakelin, Hickie, Ian B

“…Recent years have seen remarkable progress in our scientific understanding of early childhood social, emotional, and cognitive development, as well as our…”
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