Search Results - "Rohdich, F."

Biosynthesis of isoprenoids via the non-mevalonate pathway by Eisenreich, W, Bacher, A, Arigoni, D, Rohdich, F

“…The mevalonate pathway for the biosynthesis of the universal terpenoid precursors, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), is…”
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Isoprenoid biosynthetic pathways as anti-infective drug targets by Rohdich, F, Bacher, A, Eisenreich, W

“…IPP (isopentenyl diphosphate) and DMAPP (dimethylallyl diphosphate) serve as the universal precursors for the biosynthesis of isoprenoids. Besides the…”
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The deoxyxylulose phosphate pathway of isoprenoid biosynthesis. Discovery and function of the ispDEFGH genes and their cognate enzymes by Rohdich, F., Hecht, Stefan, Bacher, Adelbert, Eisenreich, Wolfgang

“…Isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) serve as the universal precursors for the biosynthesis of terpenes. Besides the well-known…”
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Anti-malarial drug targets: Screening for inhibitors of 2C-methyl- d-erythritol 4-phosphate synthase (IspC protein) in Mediterranean plants by Kaiser, J., Yassin, M., Prakash, S., Safi, N., Agami, M., Lauw, S., Ostrozhenkova, E., Bacher, A., Rohdich, F., Eisenreich, W., Safi, J., Golan-Goldhirsh, A.

“…The recently discovered non-mevalonate pathway of isoprenoid biosynthesis serves as the unique source of terpenoids in numerous pathogenic eubacteria and in…”
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Biosynthesis of Terpenoids:  Efficient Multistep Biotransformation Procedures Affording Isotope-Labeled 2C-Methyl-d-erythritol 4-Phosphate Using Recombinant 2C-Methyl-d-erythritol 4-Phosphate Synthase by Hecht, Stefan, Wungsintaweekul, Juraithip, Rohdich, Felix, Kis, Klaus, Radykewicz, Tanja, Schuhr, Christoph A, Eisenreich, Wolfgang, Richter, Gerald, Bacher, Adelbert

“…This paper describes the recombinant expression of the ispC gene of Escherichia coli specifying 2C-methyl-d-erythritol 4-phosphate synthase in a modified form…”
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Enzyme-Assisted Preparation of Isotope-Labeled 1-Deoxy-d-xylulose 5-Phosphate by Hecht, Stefan, Kis, Klaus, Eisenreich, Wolfgang, Amslinger, Sabine, Wungsintaweekul, Juraithip, Herz, Stefan, Rohdich, Felix, Bacher, Adelbert

“…Recombinant 1-deoxy-d-xylulose 5-phosphate synthase of Bacillus subtilis was used for the preparation of isotope-labeled 1-deoxy-d-xylulose 5-phosphate using…”
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566P A multicenter, open-label, dose-escalation, first-in-man study of MetAP2 inhibitor M8891 in patients with advanced solid tumours by Carducci, M.A., Wang, D., Habermehl, C., Bödding, M., Rohdich, F., Stinchi, S., Karpenko, O., Gimmi, C., LoRusso, P.

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Biosynthesis of Isoprenoids. A Rapid Method for the Preparation of Isotope-Labeled 4-Diphosphocytidyl-2C-methyl-d-erythritol by Rohdich, Felix, Schuhr, Christoph A, Hecht, Stefan, Herz, Stefan, Wungsintaweekul, Juraithip, Eisenreich, Wolfgang, Zenk, Meinhart H, Bacher, Adelbert

“…4-Diphosphocytidyl-2C-methyl-d-erythritol serves as an intermediate in the nonmevalonate pathway of isoprenoid biosynthesis. The compound has been prepared in…”
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Deoxyxylulose phosphate pathway to terpenoids by Eisenreich, Wolfgang, Rohdich, Felix, Bacher, Adelbert

“…Recently, a mevalonate-independent pathway was discovered in bacteria and plants that leads to the formation of isopentenyl diphosphate and dimethylallyl…”
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Purification and characterization of novel enzymes in terpenoid biosynthesis by Wungsintaweekul, J, Rohdich, F, Kis, K, Eisenreich, W, Schuhr, C.A, Hecht, S, Bacher, A, Sagner, S, Fellermeier, M, Zenk, M.H

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Dihydroneopterin triphosphate epimerase of Escherichia coli: purification, genetic cloning, and expression by Haussmann, C, Rohdich, F, Lottspeich, F, Eberhardt, S, Scheuring, J, Mackamul, S, Bacher, A

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development by Steinbacher, Stefan, Kaiser, Johannes, Eisenreich, Wolfgang, Huber, Robert, Bacher, Adelbert, Rohdich, Felix

“…2-C-Methyl-d-erythritol 4-phosphate synthase (IspC) is the first enzyme committed to isoprenoid biosynthesis in the methylerythritol phosphate pathway, which…”
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Studies on the Nonmevalonate Terpene Biosynthetic Pathway: Metabolic Role of IspH (LytB) Protein by Rohdich, Felix, Hecht, Stefan, Gärtner, Katrin, Adam, Petra, Krieger, Cornelia, Amslinger, Sabine, Arigoni, Duilio, Bacher, Adelbert, Eisenreich, Wolfgang

“…Isopentenyl diphosphate and dimethylallyl diphosphate serve as the universal precursors for the biosynthesis of terpenes. Although their biosynthesis by means…”
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The non-mevalonate pathway of isoprenoids: genes, enzymes and intermediates by Rohdich, Felix, Kis, Klaus, Bacher, Adelbert, Eisenreich, Wolfgang

“…Although the mevalonate pathway had been considered for a long time as the unique source of biosynthetic isoprenoids, an alternative pathway has recently been…”
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The Deoxyxylulose Phosphate Pathway of Isoprenoid Biosynthesis: Studies on the Mechanisms of the Reactions Catalyzed by IspG and IspH Protein by Rohdich, Felix, Zepeck, Ferdinand, Adam, Petra, Hecht, Stefan, Kaiser, Johannes, Laupitz, Ralf, Gräwert, Tobias, Amslinger, Sabine, Eisenreich, Wolfgang, Bacher, Adelbert, Arigoni, Duilio

“…Earlier in vivo studies have shown that the sequential action of the IspG and IspH proteins is essential for the reductive transformation of…”
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Studies on the Nonmevalonate Pathway to Terpenes: The Role of the GcpE (IspG) Protein by Hecht, Stefan, Eisenreich, Wolfgang, Adam, Petra, Amslinger, Sabine, Kis, Klaus, Bacher, Adelbert, Arigoni, Duilio, Rohdich, Felix

“…Recombinant Escherichia coli cells engineered for the expression of the xylB gene in conjunction with genes of the nonmevalonate pathway were supplied…”
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IspH Protein of Escherichia coli:  Studies on Iron−Sulfur Cluster Implementation and Catalysis by GRäWERT, Tobias, KAISER, Johannes, ZEPECK, Ferdinand, LAUPITZ, Ralf, HECHT, Stefan, AMSLINGER, Sabine, SCHRAMEK, Nicholas, SCHLEICHER, Erik, WEBER, Stefan, HASLBECK, Martin, BUCHNER, Johannes, RIEDER, Christoph, ARIGONI, Duilio, BACHER, Adelbert, EISENREICH, Wolfgang, ROHDICH, Felix

“…The ispH gene of Escherichia coli specifies an enzyme catalyzing the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl diphosphate into a mixture of isopentenyl…”
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Biosynthesis of Terpenes: Studies on 1-Hydroxy-2-Methyl-2-(E)-Butenyl 4-Diphosphate Reductase by Adam, Petra, Hecht, Stefan, Eisenreich, Wolfgang, Kaiser, Johannes, Gräwert, Tobias, Arigoni, Duilio, Bacher, Adelbert, Rohdich, Felix

“…Earlier in vivo studies showed the involvement of IspH protein in the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate…”
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Cytidine 5′-Triphosphate-Dependent Biosynthesis of Isoprenoids: YgbP Protein of Escherichia coli Catalyzes the Formation of 4-diphosphocytidyl-2-C-methylerythritol by Rohdich, Felix, Wungsintaweekul, Juraithip, Fellermeier, Monika, Sagner, Silvia, Herz, Stefan, Kis, Klaus, Eisenreich, Wolfgang, Bacher, Adelbert, Zenk, Meinhart H.

“…2-C-methylerythritol 4-phosphate has been established recently as an intermediate of the deoxyxylulose phosphate pathway used for biosynthesis of terpenoids in…”
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Biosynthesis of Isoprenoids. Purification and Properties of IspG Protein from Escherichia coli by Zepeck, Ferdinand, Gräwert, Tobias, Kaiser, Johannes, Schramek, Nicholas, Eisenreich, Wolfgang, Bacher, Adelbert, Rohdich, Felix

“…The IspG protein is known to catalyze the transformation of 2-C-methyl-d-erythritol 2,4-cyclodiphosphate into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate in…”
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