Search Results - "Rohde, Gernot G U"

Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles by Benedikter, Birke J., Bouwman, Freek G., Heinzmann, Alexandra C. A., Vajen, Tanja, Mariman, Edwin C., Wouters, Emiel F. M., Savelkoul, Paul H. M., Koenen, Rory R., Rohde, Gernot G. U., van Oerle, Rene, Spronk, Henri M., Stassen, Frank R. M.

“…Airway epithelial cells secrete extracellular vesicles (EVs) under basal conditions and when exposed to cigarette smoke extract (CSE). Getting insights into…”
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Antibiotics for community-acquired pneumonia in adult outpatients by Pakhale, Smita, Mulpuru, Sunita, Verheij, Theo J M, Kochen, Michael M, Rohde, Gernot G U, Bjerre, Lise M

“…Lower respiratory tract infection (LRTI) is the third leading cause of death worldwide and the first leading cause of death in low-income countries…”
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Viral-bacterial interactions in the respiratory tract by Bellinghausen, Carla, Rohde, Gernot G U, Savelkoul, Paul H M, Wouters, Emiel F M, Stassen, Frank R M

“…In the respiratory tract, viruses and bacteria can interact on multiple levels. It is well known that respiratory viruses, particularly influenza viruses,…”
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Characteristics, clinical course and outcome of ventilated patients at a non-surgical intensive care unit in Germany: a single-centre, retrospective observational cohort analysis by Grünewaldt, Achim, Peiffer, Kai-Henrik, Bojunga, Jörg, Rohde, Gernot G U

“…ObjectivesThe objective of this study was to evaluate epidemiological characteristics, clinical course and outcome of mechanically ventilated non-surgical…”
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Adrenomedullin refines mortality prediction by the BODE index in COPD: the BODE-A index by STOLZ, Daiana, KOSTIKAS, Kostantinos, ROHDE, Gernot G. U, BOECK, Lucas, RAKIC, Janko, SCHERR, Andreas, HERTEL, Sabine, GIERSDORF, Sven, TAMM, Michael, BLASI, Francesco, BOERSMA, Wim, MILENKOVIC, Branislava, LACOMA, Alicia, LOUIS, Renaud, AERTS, Joachim G, WELTE, Tobias, TORRES, Antoni

“…The BODE (body mass index, airflow obstruction, dyspnoea, exercise capacity) index is well-validated for mortality prediction in chronic obstructive pulmonary…”
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Implementation and use of mHealth home telemonitoring in adults with acute COVID-19 infection: a scoping review protocol by Dauletbaev, Nurlan, Kuhn, Sebastian, Holtz, Svea, Waldmann, Susanne, Niekrenz, Lukas, Müller, Beate S, Bellinghausen, Carla, Dreher, Michael, Rohde, Gernot G U, Vogelmeier, Claus

“…IntroductionmHealth refers to digital technologies that, via smartphones, mobile apps and specialised digital sensors, yield real-time assessments of patient’s…”
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Perceptions of people with respiratory problems on physician performance evaluation—A qualitative study by Sehlbach, Carolin, Govaerts, Marjan J. B., Mitchell, Sharon, Teunissen, Truus G. J., Smeenk, Frank W. J. M., Driessen, Erik W., Rohde, Gernot G. U.

“…Background Despite increasing calls for patient and public involvement in health‐care quality improvement, the question of how patient evaluations can…”
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Mannose-binding lectin protein and its association to clinical outcomes in COPD: a longitudinal study by Mandal, Jyotshna, Malla, Bijaya, Steffensen, Rudi, Costa, Luigi, Egli, Adrian, Trendelenburg, Marten, Blasi, Francesco, Kostikas, Kostantinos, Welte, Tobias, Torres, Antoni, Louis, Renaud, Boersma, Wim, Milenkovic, Branislava, Aerts, Joachim, Rohde, Gernot G U, Lacoma, Alicia, Rentsch, Katharina, Roth, Michael, Tamm, Michael, Stolz, Daiana

“…Functional deficiency of mannose-binding lectin (MBL) may contribute to the pathogenesis of chronic obstructive pulmonary disease. We hypothesized that…”
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Risk stratification for short‐term mortality at hospital admission for acute exacerbations of COPD by Sprooten, Roy T.M., Rohde, Gernot G.U., Lawyer, Glenn, Leijte, Wouter T., Wouters, Emiel F.M., Franssen, Frits M.E.

“…ABSTRACT Background and objective Exacerbations of chronic obstructive pulmonary disease (ECOPD) are associated with increased in‐hospital and short‐term…”
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Therapy with proton-pump inhibitors for gastroesophageal reflux disease does not reduce the risk for severe exacerbations in COPD by Baumeler, Luzia, Papakonstantinou, Eleni, Milenkovic, Branislava, Lacoma, Alicia, Louis, Renaud, Aerts, Joachim G., Welte, Tobias, Kostikas, Konstantinos, Blasi, Francesco, Boersma, Wim, Torres, Antoni, Rohde, Gernot G.U., Boeck, Lucas, Rakic, Janko, Scherr, Andreas, Tamm, Michael, Stolz, Daiana

“…Background and objective Gastroesophageal reflux disease (GERD) symptoms are associated with a higher risk of chronic obstructive pulmonary disease (COPD)…”
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IFNΛ3/4 locus polymorphisms and IFNΛ3 circulating levels are associated with COPD severity and outcomes by Egli, Adrian, Mandal, Jyotshna, Schumann, Desiree M, Roth, Michael, Thomas, Brad, Lorne Tyrrell, D, Blasi, Francesco, Kostikas, Kostantinos, Boersma, Wim, Milenkovic, Branislava, Lacoma, Alicia, Rentsch, Katharina, Rohde, Gernot G U, Louis, Renaud, Aerts, Joachim G, Welte, Tobias, Torres, Antoni, Tamm, Michael, Stolz, Daiana

“…Interferon lambdas (IFNLs) have important anti-viral/bacterial and immunomodulatory functions in the respiratory tract. How do IFNLs impact COPD and its…”
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Impact of exacerbations on adherence and outcomes of pulmonary rehabilitation in patients with COPD by Braeken, Dionne C.W., Spruit, Martijn A., Houben‐Wilke, Sarah, Smid, Dionne E., Rohde, Gernot G.U., Wouters, Emiel F.M., Franssen, Frits M.E.

“…ABSTRACT Background and objective Dropout or lack of response is an important issue in pulmonary rehabilitation (PR), which underlines the need to identify…”
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Burden of COPD in patients treated in different care settings in the Netherlands by Smid, Dionne E, Spruit, Martijn A, Houben-Wilke, Sarah, Muris, Jean W.M, Rohde, Gernot G.U, Wouters, Emiel F.M, Franssen, Frits M.E

“…Abstract Introduction Care for patients with chronic obstructive pulmonary disease (COPD) can be provided in primary, secondary or tertiary care. Whether and…”
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Similar matrix alterations in alveolar and small airway walls of COPD patients by Eurlings, Irene M J, Dentener, Mieke A, Cleutjens, Jack P M, Peutz, Carine J, Rohde, Gernot G U, Wouters, Emiel F M, Reynaert, Niki L

“…Remodelling in COPD has at least two dimensions: small airway wall thickening and destruction of alveolar walls. Recent studies indicate that there is some…”
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Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies by Benedikter, Birke J., Bouwman, Freek G., Vajen, Tanja, Heinzmann, Alexandra C. A., Grauls, Gert, Mariman, Edwin C., Wouters, Emiel F. M., Savelkoul, Paul H., Lopez-Iglesias, Carmen, Koenen, Rory R., Rohde, Gernot G. U., Stassen, Frank R. M.

“…Appropriate isolation methods are essential for unravelling the relative contribution of extracellular vesicles (EVs) and the EV-free secretome to homeostasis…”
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Redox-dependent thiol modifications: implications for the release of extracellular vesicles by Benedikter, Birke J., Weseler, Antje R., Wouters, Emiel F. M., Savelkoul, Paul H. M., Rohde, Gernot G. U., Stassen, Frank R. M.

“…Extracellular vesicles (EVs), including microvesicles and exosomes, are emerging as important regulators of homeostasis and pathophysiology. During…”
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A pathway to keep all lifelong learners up to date: the ERS continuing professional development programme by Farr, Amy, Aliberti, Stefano, Loukides, Stelios, Massard, Gilbert, Primhak, Robert, Rohde, Gernot G U, Tabin, Nathalie, Pannetier, Carine, Stolz, Daiana

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Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants by Benedikter, Birke J., Volgers, Charlotte, van Eijck, Pascalle H., Wouters, Emiel F.M., Savelkoul, Paul H.M., Reynaert, Niki L., Haenen, Guido R.M.M., Rohde, Gernot G.U., Weseler, Antje R., Stassen, Frank R.M.

“…Airway epithelial cells have been described to release extracellular vesicles (EVs) with pathological properties when exposed to cigarette smoke extract (CSE)…”
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Serum levels of hyaluronic acid are associated with COPD severity and predict survival by Papakonstantinou, Eleni, Bonovolias, Ioannis, Roth, Michael, Tamm, Michael, Schumann, Desiree, Baty, Florent, Louis, Renaud, Milenkovic, Branislava, Boersma, Wim, Stieltjes, Bram, Kostikas, Konstantinos, Blasi, Francesco, Aerts, Joachim G, Rohde, Gernot G U, Lacoma, Alicia, Torres, Antoni, Welte, Tobias, Stolz, Daiana

“…Hyaluronic acid (HA) and its degradation products play an important role in lung pathophysiology and airway remodelling in chronic obstructive pulmonary…”
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Learning in the workplace: Use of informal feedback cues in doctor‐patient communication by Sehlbach, Carolin, Teunissen, Pim W., Driessen, Erik W., Mitchell, Sharon, Rohde, Gernot G. U., Smeenk, Frank W. J. M., Govaerts, Marjan J. B.

“…Objectives We expect physicians to be lifelong learners. Participation in clinical practice is an important potential source of that learning. To support…”
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