Search Results - "Rohaim, Mohammed A."
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Structural topological analysis of spike proteins of SARS-CoV-2 variants of concern highlight distinctive amino acid substitution patterns
Published in European journal of cell biology (01-09-2022)“…Since the onset of pandemic in 2019, SARS-CoV-2 has diverged into numerous variants driven by antigenic and infectivity-oriented selection. Some variants have…”
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2
Application of CRISPR/Cas9 in Understanding Avian Viruses and Developing Poultry Vaccines
Published in Frontiers in cellular and infection microbiology (24-11-2020)“…Clustered regularly interspaced short palindromic repeats associated protein nuclease 9 (CRISPR-Cas9) technology offers novel approaches to precisely,…”
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3
Respiratory disease complex due to mixed viral infections in chicken in Jordan
Published in Poultry science (01-04-2024)“…The global distribution of avian respiratory viruses highlights the need for effective surveillance programs and international collaboration to monitor viral…”
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4
A Scalable Topical Vectored Vaccine Candidate against SARS-CoV-2
Published in Vaccines (Basel) (24-08-2020)“…The severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) caused an ongoing unprecedented global public health crises of coronavirus disease in 2019…”
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5
Transgenic Chicks Expressing Interferon-Inducible Transmembrane Protein 1 (IFITM1) Restrict Highly Pathogenic H5N1 Influenza Viruses
Published in International journal of molecular sciences (06-08-2021)“…Mammalian cells utilize a wide spectrum of pathways to antagonize the viral replication. These pathways are typically regulated by antiviral proteins and can…”
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6
Genetic Diversity and Phylodynamics of Avian Coronaviruses in Egyptian Wild Birds
Published in Viruses (14-01-2019)“…Avian coronaviruses (ACoVs) are continuously evolving and causing serious economic consequences in the poultry industry and around the globe. Owing to their…”
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7
Interferon-induced protein with tetratricopeptide repeats 5 of black fruit bat ( Pteropus alecto ) displays a broad inhibition of RNA viruses
Published in Frontiers in immunology (19-02-2024)“…Bats are natural host reservoirs and have adapted a unique innate immune system that permits them to host many viruses without exhibiting symptoms. Notably,…”
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Artificial Intelligence-Assisted Loop Mediated Isothermal Amplification (AI-LAMP) for Rapid Detection of SARS-CoV-2
Published in Viruses (01-09-2020)“…Until vaccines and effective therapeutics become available, the practical solution to transit safely out of the current coronavirus disease 19 (CoVID-19)…”
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Avian Orthoavulavirus Type-1 as Vaccine Vector against Respiratory Viral Pathogens in Animal and Human
Published in Vaccines (Basel) (08-02-2022)“…Avian orthoavulaviruses type-1 (AOaV-1) have recently transitioned from animal vaccine vector to a bona fide vaccine delivery vehicle in human. Owing to…”
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10
Structural and Virus Regulatory Insights Into Avian N6-Methyladenosine (m6A) Machinery
Published in Frontiers in cell and developmental biology (15-07-2020)“…The addition of a methyl group to the N6 position of adenosine (m6A) is the most common posttranscriptional RNA modification, and it regulates most steps of…”
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Chickens Expressing IFIT5 Ameliorate Clinical Outcome and Pathology of Highly Pathogenic Avian Influenza and Velogenic Newcastle Disease Viruses
Published in Frontiers in immunology (14-09-2018)“…Innate antiviral immunity establishes first line of defense against invading pathogens through sensing their molecular structures such as viral RNA. This…”
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12
Immunogenicity and protective efficacy of an intranasal live-attenuated vaccine against SARS-CoV-2
Published in iScience (24-09-2021)“…Global deployment of an effective and safe vaccine is necessary to curtail the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome…”
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13
Genome-Wide Classification of Type I, Type II and Type III Interferon-Stimulated Genes in Chicken Fibroblasts
Published in Vaccines (Basel) (25-10-2019)“…Interferons (IFNs) play central roles in establishing innate immunity and mediating adaptive immunity against multiple pathogens. Three known types of IFNs…”
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14
Structural Bases of Zoonotic and Zooanthroponotic Transmission of SARS-CoV-2
Published in Viruses (17-02-2022)“…The emergence of multiple variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) highlights the importance of possible animal-to-human…”
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Deep Structural Analysis of Myriads of Omicron Sub-Variants Revealed Hotspot for Vaccine Escape Immunity
Published in Vaccines (Basel) (01-03-2023)“…The emergence of the Omicron variant has reinforced the importance of continued SARS-CoV-2 evolution and its possible impact on vaccine effectiveness…”
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16
Genetic Diversity of Newcastle Disease Virus Involved in the 2021 Outbreaks in Backyard Poultry Farms in Tanzania
Published in Veterinary sciences (21-07-2023)“…Newcastle disease virus is a significant avian pathogen with the potential to decimate poultry populations all over the world and cause enormous economic…”
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Evolutionary Trajectories of Avian Avulaviruses and Vaccines Compatibilities in Poultry
Published in Vaccines (Basel) (03-11-2022)“…Newcastle disease virus (NDV) causes one of the highly infectious avian diseases in poultry leading to genuine financial misfortunes around the world…”
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Insights into the Genetic Evolution of Duck Hepatitis A Virus in Egypt
Published in Animals (Basel) (19-09-2021)“…Duck hepatitis virus (DHV) is one of the commercially important diseases of ducklings worldwide. It is an acute and highly infectious disease of ducklings…”
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Structural and functional insights into non-structural proteins of coronaviruses
Published in Microbial pathogenesis (01-01-2021)“…Coronaviruses (CoVs) are causing a number of human and animal diseases because of their zoonotic nature such as Middle East respiratory syndrome (MERS), severe…”
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Corrigendum: VIDIIA Hunter: a low-cost, smartphone connected, artificial intelligence-assisted COVID-19 rapid diagnostic platform approved for medical use in the UK
Published in Frontiers in molecular biosciences (31-10-2023)“…[This corrects the article DOI: 10.3389/fmolb.2023.1144001.]…”
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