Search Results - "Roh, Kyung Hye"

TRAF6-mediated ubiquitination of MST1/STK4 attenuates the TLR4-NF-κB signaling pathway in macrophages by Roh, Kyung-Hye, Lee, Yeojin, Yoon, Je-Hyun, Lee, Danbi, Kim, Eunju, Park, Eunchong, Lee, In Young, Kim, Tae Sung, Song, Hyun Kyu, Shin, Jaekyoon, Lim, Dae-Sik, Choi, Eui-Ju

“…Pattern-recognition receptors including Toll-like receptors (TLRs) recognize invading pathogens and trigger an immune response in mammals. Here we show that…”
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A novel conformation of the LC3-interacting region motif revealed by the structure of a complex between LC3B and RavZ by Kwon, Do Hoon, Kim, Leehyeon, Kim, Byeong-Won, Kim, Jun Hoe, Roh, Kyung-Hye, Choi, Eui-Ju, Song, Hyun Kyu

“…LC3-family member proteins play a critical role in autophagy, a cellular process responsible for the degradation of massive cellular components including…”
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The 1:2 complex between RavZ and LC3 reveals a mechanism for deconjugation of LC3 on the phagophore membrane by Kwon, Do Hoon, Kim, Sulhee, Jung, Yang Ouk, Roh, Kyung-Hye, Kim, Leehyeon, Kim, Byeong-Won, Hong, Seung Beom, Lee, In Young, Song, Ju Han, Lee, Woo Cheol, Choi, Eui-Ju, Hwang, Kwang Yeon, Song, Hyun Kyu

“…Hosts utilize macroautophagy/autophagy to clear invading bacteria; however, bacteria have also developed a specific mechanism to survive by manipulating the…”
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TRAF2 functions as an activator switch in the reactive oxygen species-induced stimulation of MST1 by Roh, Kyung-Hye, Choi, Eui-Ju

“…Reactive oxygen species (ROS) have many physiological and pathological effects on diverse cellular events. In particular, excessive ROS causes oxidative stress…”
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MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity by Lee, In Young, Lim, Jane Melissa, Cho, Hyunchu, Kim, Eunju, Kim, Yeonsil, Oh, Hye-Kyung, Yang, Woo Seok, Roh, Kyung-Hye, Park, Hyun Woo, Mo, Jung-Soon, Yoon, Je-Hyun, Song, Hyun Kyu, Choi, Eui-Ju

“…The nuclear factor (NF)-κB pathway plays a central role in inflammatory and immune responses, with aberrant activation of NF-κB signaling being implicated in…”
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MST1 deficiency promotes B cell responses by CD4+ T cell-derived IL-4, resulting in hypergammaglobulinemia by Park, Eunchong, Kim, Myun Soo, Song, Ju Han, Roh, Kyung-Hye, Lee, Rana, Kim, Tae Sung

“…MST1 deficiency causes T and B cell lymphopenia, resulting in combined immunodeficiency. However, MST1-deficient patients also exhibit autoimmune-like symptoms…”
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Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners by Kim, Jun Hoe, Hong, Seung Beom, Lee, Jae Keun, Han, Sisu, Roh, Kyung-Hye, Lee, Kyung-Eun, Kim, Yoon Ki, Choi, Eui-Ju, Song, Hyun Kyu

“…Autophagy is a bulky catabolic process that responds to nutrient homeostasis and extracellular stress signals and is a conserved mechanism in all eukaryotes…”
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S-nitrosylated GAPDH mediates neuronal apoptosis induced by amyotrophic lateral sclerosis-associated mutant SOD1 G93A by Lee, Rana, Lim, Jane Melissa, Roh, Kyung-Hye, Kim, Ji Hyun, Kang, Seongman, Lee, Ji Eun, Choi, Eui-Ju

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with the selective loss of motor neurons in the brain, brain stem, and spinal cord. A number…”
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CIIA negatively regulates the Ras-Erk1/2 signaling pathway through inhibiting the Ras-specific GEF activity of SOS1 by Hwang, Hyun Sub, Hwang, Sang Gil, Yoon, Kyoung-Wan, Yoon, Je-Hyun, Roh, Kyung-Hye, Choi, Eui-Ju

“…Son of sevenless 1 (SOS1) is a Ras-specific guanine-nucleotide-exchange factor (GEF) that mediates intracellular signaling processes induced by receptor…”
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eIF4E phosphorylation by MST1 reduces translation of a subset of mRNAs, but increases lncRNA translation by Min, Kyung-Won, Davila, Sylvia, Zealy, Richard W., Lloyd, Lawson T., Lee, In Young, Lee, Rumi, Roh, Kyung Hye, Jung, Ahjin, Jemielity, Jacek, Choi, Eui-Ju, Chang, Jeong Ho, Yoon, Je-Hyun

“…Post-transcriptional gene regulation is an important step in eukaryotic gene expression. The last step to govern production of nascent peptides is during the…”
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S-nitrosylated GAPDH mediates neuronal apoptosis induced by amyotrophic lateral sclerosis-associated mutant SOD1 super(G93A) by Lee, Rana, Lim, Jane Melissa, Roh, Kyung-Hye, Kim, Ji Hyun, Kang, Seongman, Lee, Ji Eun, Choi, Eui-Ju

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with the selective loss of motor neurons in the brain, brain stem, and spinal cord. A number…”
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S-nitrosylated GAPDH mediates neuronal apoptosis induced by amyotrophic lateral sclerosis-associated mutant SOD1 G93A by Lee, Rana, Lim, Jane Melissa, Roh, Kyung-Hye, Kim, Ji Hyun, Kang, Seongman, Lee, Ji Eun, Choi, Eui-Ju

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S-nitrosylated GAPDH mediates neuronal apoptosis induced by amyotrophic lateral sclerosis-associated mutant SOD1G93A by Lee, Rana, Lim, Jane Melissa, Roh, Kyung-Hye, Kim, Ji Hyun, Kang, Seongman, Lee, Ji Eun, Choi, Eui-Ju

“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with the selective loss of motor neurons in the brain, brain stem, and spinal cord. A number…”
Get full text