Search Results - "Rognes, T"

DNA Repair in Mammalian Cells by Robertson, A. B, Klungland, A, Rognes, T, Leiros, I

“…Base excision repair (BER) is the primary DNA repair pathway that corrects base lesions that arise due to oxidative, alkylation, deamination, and…”
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Six-fold speed-up of Smith–Waterman sequence database searches using parallel processing on common microprocessors by Rognes, Torbjørn, Seeberg, Erling

“…Motivation: Sequence database searching is among the most important and challenging tasks in bioinformatics. The ultimate choice of sequence-search algorithm…”
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Characterization of novel mutations in the catalytic domain of the PCSK9 gene by Cameron, J., Holla, Ø. L., Laerdahl, J. K., Kulseth, M. A., Ranheim, T., Rognes, T., Berge, K. E., Leren, T. P.

“… Objectives.  To expand our understanding of the structure and function of proprotein convertase subtilisin/kexin type 9 (PCSK9) by studying how naturally…”
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Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in human DNA repair genes by Nakken, S, Alseth, I, Rognes, T

“…Abstract Non-synonymous single nucleotide polymorphisms (nsSNPs) represent common genetic variation that alters encoded amino acids in proteins. All nsSNPs may…”
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ParAlign: a parallel sequence alignment algorithm for rapid and sensitive database searches by Rognes, T

“…There is a need for faster and more sensitive algorithms for sequence similarity searching in view of the rapidly increasing amounts of genomic sequence data…”
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DNA Repair in Mammalian Cells: Base excision repair: the long and short of it by Robertson, A. B., Klungland, A., Rognes, T., Leiros, I.

“… Base excision repair (BER) is the primary DNA repair pathway that corrects base lesions that arise due to oxidative, alkylation, deamination, and…”
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PARALIGN: rapid and sensitive sequence similarity searches powered by parallel computing technology by Sæbø, Per Eystein, Andersen, Sten Morten, Myrseth, Jon, Laerdahl, Jon K., Rognes, Torbjørn

“…PARALIGN is a rapid and sensitive similarity search tool for the identification of distantly related sequences in both nucleotide and amino acid sequence…”
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RNAmmer: consistent and rapid annotation of ribosomal RNA genes by Lagesen, Karin, Hallin, Peter, Rødland, Einar Andreas, Stærfeldt, Hans-Henrik, Rognes, Torbjørn, Ussery, David W

“…The publication of a complete genome sequence is usually accompanied by annotations of its genes. In contrast to protein coding genes, genes for ribosomal RNA…”
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disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterparts by Nakken, Sigve, Rognes, Torbjørn, Hovig, Eivind

“…Specific guanine-rich sequence motifs in the human genome have considerable potential to form four-stranded structures known as G-quadruplexes or G4 DNA. The…”
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Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8‐oxoguanine and other oxidation products in DNA by Morland, Ingrid, Rolseth, Veslemøy, Luna, Luisa, Rognes, Torbjørn, Bjørås, Magnar, Seeberg, Erling

“…The mild phenotype associated with targeted disruption of the mouse OGG1 and NTH1 genes has been attributed to the existence of back‐up activities and/or…”
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Base removers and strand scissors: different strategies employed in base excision and strand incision at modified base residues in DNA by Seeberg, E, Luna, L, Morland, I, Eide, L, Johnsen, B, Larsen, E, Alseth, I, Dantzer, F, Baynton, K, Aamodt, R, Kristiansen, K I, Rognes, T, Klungland, A, Bjørås, M

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Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites by Bjørås, Magnar, Luna, Luisa, Johnsen, Barbro, Hoff, Elsebeth, Haug, Terje, Rognes, Torbjørn, Seeberg, Erling

“…The guanine modification 7,8‐dihydro‐8‐oxoguanine (8‐oxoG) is a potent premutagenic lesion formed spontaneously at high frequencies in the genomes of aerobic…”
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Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in human DNA repair genes: Genome dynamics and DNA repair in the CNS by NAKKEN, S, ALSETH, I, ROGNES, T

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The Saccharomyces cerevisiae Homologues of Endonuclease III from Escherichia coli, Ntg1 and Ntg2, Are Both Required for Efficient Repair of Spontaneous and Induced Oxidative DNA Damage in Yeast by Alseth, Ingrun, Eide, Lars, Pirovano, Manuela, Rognes, Torbjørn, Seeberg, Erling, Bjørås, Magnar

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Biased distribution of DNA uptake sequences towards genome maintenance genes by Davidsen, Tonje, Rødland, Einar A., Lagesen, Karin, Seeberg, Erling, Rognes, Torbjørn, Tønjum, Tone

“…Repeated sequence signatures are characteristic features of all genomic DNA. We have made a rigorous search for repeat genomic sequences in the human pathogens…”
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new protein superfamily includes two novel 3‐methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD by Alseth, Ingrun, Rognes, Torbjørn, Lindbäck, Toril, Solberg, Inger, Robertsen, Kristin, Kristiansen, Knut Ivan, Mainieri, Davide, Lillehagen, Lucy, Kolstø, Anne‐Brit, Bjørås, Magnar

“…Soil bacteria are heavily exposed to environmental methylating agents such as methylchloride and may have special requirements for repair of alkylation damage…”
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Incision at hypoxanthine residues in DNA by a mammalian homologue of the Escherichia coli antimutator enzyme endonuclease V by Moe, Ane, Ringvoll, Jeanette, Nordstrand, Line M., Eide, Lars, Bjørås, Magnar, Seeberg, Erling, Rognes, Torbjørn, Klungland, Arne

“…Deamination of DNA bases can occur spontaneously, generating highly mutagenic lesions such as uracil and hypoxanthine. In Escherichia coli two enzymes initiate…”
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Predicting non-coding RNA genes in Escherichia coli with boosted genetic programming by Sætrom, Pål, Sneve, Ragnhild, Kristiansen, Knut I., Snøve, Ola, Grünfeld, Thomas, Rognes, Torbjørn, Seeberg, Erling

“…Several methods exist for predicting non-coding RNA (ncRNA) genes in Escherichia coli (E.coli). In addition to about sixty known ncRNA genes excluding tRNAs…”
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DNA repair by bacterial AlkB proteins by Falnes, Pål Ø., Rognes, Torbjørn

“…The Escherichia coli AlkB protein is an iron- and 2-oxoglutarate-dependent oxygenase, repairing 1-methyladenine and 3-methylcytosine lesions in DNA. AlkB…”
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Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA by Morland, I, Rolseth, V, Luna, L, Rognes, T, Bjoeras, M, Seeberg, E

“…The authors wish it to be known that, in their opinion, the first two authors should be regarded as joint First Authors The mild phenotype associated with…”
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