Search Results - "Rogler, Anja"
-
1
The plasmacytoid carcinoma of the bladder—rare variant of aggressive urothelial carcinoma
Published in International journal of cancer (15-07-2011)“…The WHO 2004 classification defines new histological and molecular variants of urothelial carcinoma. However, there are limited data available on the…”
Get full text
Journal Article -
2
Fibroblast growth factor receptor (FGFR) gene amplifications are rare events in bladder cancer
Published in Histopathology (01-04-2015)“…Aims Activating point mutations and protein overexpression of fibroblast growth factor receptors (FGFRs), especially FGFR3, are frequent events in bladder…”
Get full text
Journal Article -
3
TERT Core Promotor Mutations in Early-Onset Bladder Cancer
Published in Journal of Cancer (01-01-2016)“…Activating mutations in the core promoter of the TERT gene have been described in many different tumor entities. In vitro models showed a two- to fourfold…”
Get full text
Journal Article -
4
Endocan Is Upregulated on Tumor Vessels in Invasive Bladder Cancer Where It Mediates VEGF-A―Induced Angiogenesis
Published in Cancer research (Chicago, Ill.) (01-02-2013)“…Tumor-associated blood vessels differ from normal vessels and proteins present only on tumor vessels may serve as biomarkers or targets for antiangiogenic…”
Get full text
Journal Article -
5
The EVERPRO study: Final results of a non-interventional study (NIS) evaluating the quality of life (QoL) in second-line treatment of metastatic renal cell carcinoma (mRCC) with everolimus
Published in Journal of clinical oncology (20-02-2018)“…Abstract only 631 The EVERPRO study: Final results of a non-interventional study evaluating QoL in second-line treatment of mRCC with everolimus Background:…”
Get full text
Journal Article -
6
Sequential treatment with pazopanib (PAZO) followed by nivolumab (NIVO) in patients with advanced or metastatic renal cell carcinoma (mRCC): Third interim results of the non-interventional study PAZOREAL
Published in Journal of clinical oncology (20-05-2019)“…Abstract only 4574 Background: Randomized clinical trials for the implementation of new therapies include only a selection of patients that are later treated…”
Get full text
Journal Article -
7
Methylation-dependent activation of CDX1 through NF-κB: a link from inflammation to intestinal metaplasia in the human stomach
Published in The American journal of pathology (01-08-2012)“…The caudal homeobox factor 1 (CDX1) is an essential transcription factor for intestinal differentiation. Its aberrant expression in intestinal metaplasia of…”
Get full text
Journal Article -
8
Abstract 3862: Functional characterization of sFRP1 expression loss in human papillary bladder cancer
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract Introduction: Secreted frizzled-related protein 1 (sFRP1) is an inhibitor of the Wnt-signaling pathway and expression loss is associated with e.g…”
Get full text
Journal Article -
9
Functional analyses and prognostic significance of SFRP1 expression in bladder cancer
Published in Journal of cancer research and clinical oncology (01-10-2015)“…Purpose We previously showed that the Wnt-signaling antagonist SFRP1 (secreted frizzled-related protein 1) is a promising marker in bladder cancer. The aim of…”
Get full text
Journal Article -
10
Loss of MTUS1/ATIP expression is associated with adverse outcome in advanced bladder carcinomas: data from a retrospective study
Published in BMC cancer (20-03-2014)“…Seventy percent of all bladder tumours tend to recur and need intensive surveillance, and a subset of tumours progress to muscle-invasive and metastatic…”
Get full text
Journal Article -
11
Abstract 1164: MTUS1 as a potential progression marker at chromosome 8p in bladder cancer
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Aims and background: The search for sensitive and specific progression and recurrence markers in bladder cancer is a major focus of many urological…”
Get full text
Journal Article -
12
Abstract 3893: Endocan is upregulated on tumor vessels in invasive bladder cancer and mediates VEGF-A-induced angiogenesis
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…Abstract Tumor-associated blood vessels differ from normal vessels at the morphological and molecular level. Proteins that are only present on tumor vessels…”
Get full text
Journal Article -
13
Role of two single nucleotide polymorphisms in secreted frizzled related protein 1 and bladder cancer risk
Published in International journal of clinical and experimental pathology (01-01-2013)“…In this study, we determined the genotype distribution of two single nucleotide polymorphisms (SNPs) in secreted frizzled related protein 1 (SFRP1), rs3242 and…”
Get full text
Journal Article -
14
Frequency of activating mutations in FGFR2 exon 7 in bladder tumors from patients with early-onset and regular-onset disease
Published in International journal of clinical and experimental pathology (01-01-2014)“…The FGF/FGFR-system plays an important role in embryogenesis, tissue homeostasis and carcinogenesis. Mutational activation of FGFR2 resulting in aberrant FGFR2…”
Get full text
Journal Article -
15
P53 codon 72 (Arg72Pro) polymorphism and prostate cancer risk: association between disease onset and proline genotype
Published in Pathobiology (Basel) (01-07-2011)“…The tumor suppressor gene p53 plays an important role in the stress response of the cell and is mutated in 50% of all human tumors. The p53 Arg72Pro…”
Get more information
Journal Article -
16
Methylation-Dependent Activation of CDX1 through NF-κB
Published in The American journal of pathology (01-08-2012)“…The caudal homeobox factor 1 (CDX1) is an essential transcription factor for intestinal differentiation. Its aberrant expression in intestinal metaplasia of…”
Get full text
Journal Article -
17
Abstract 1840: P53 codon 72 SNP (R72P) and prostate cancer risk
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract Aims: The tumor suppressor p53 plays a major role in stress responses of the cell and modulates cell cycle arrest and apoptosis. The p53 R72P SNP…”
Get full text
Journal Article -
18
-
19
Abstract 784: Plasmacytoid urothelial carcinoma: Molecular and histopathological characterization of a rare variant of bladder cancer
Published in Cancer research (Chicago, Ill.) (15-04-2010)“…Abstract AIM: The plasmaycytoid urothelial carcinoma (PUC) is a rare variant of urothelial carcinoma. To date only few cases have been reported and molecular…”
Get full text
Journal Article -
20