Search Results - "Rogers, Lindsay D."

Proteolytic Post-translational Modification of Proteins: Proteomic Tools and Methodology by Rogers, Lindsay D., Overall, Christopher M.

“…Proteolytic processing is a ubiquitous and irreversible post-translational modification involving limited and highly specific hydrolysis of peptide and…”
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Interactome disassembly during apoptosis occurs independent of caspase cleavage by Scott, Nichollas E, Rogers, Lindsay D, Prudova, Anna, Brown, Nat F, Fortelny, Nikolaus, Overall, Christopher M, Foster, Leonard J

“…Protein–protein interaction networks (interactomes) define the functionality of all biological systems. In apoptosis, proteolysis by caspases is thought to…”
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dynamic phagosomal proteome and the contribution of the endoplasmic reticulum by Rogers, Lindsay D, Foster, Leonard J

“…Macrophages use phagocytosis to control the spread of pathogens in the body, to clear apoptotic cells, and to aid in tissue remodeling. The phagosomal membrane…”
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iRhom2 regulates CSF1R cell surface expression and non‐steady state myelopoiesis in mice by Qing, Xiaoping, D. Rogers, Lindsay, Mortha, Arthur, Lavin, Yonit, Redecha, Patricia, Issuree, Priya D., Maretzky, Thorsten, Merad, Miriam, R. McIlwain, David, Mak, Tak W., Overall, Christopher M., Blobel, Carl P., Salmon, Jane E.

“…CSF1R (colony stimulating factor 1 receptor) is the main receptor for CSF1 and has crucial roles in regulating myelopoeisis. CSF1R can be proteolytically…”
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Global Impact of Salmonella Pathogenicity Island 2-secreted Effectors on the Host Phosphoproteome by Imami, Koshi, Bhavsar, Amit P., Yu, Hongbing, Brown, Nat F., Rogers, Lindsay D., Finlay, B. Brett, Foster, Leonard J.

“…During the late stages of infection, Salmonella secretes numerous effectors through a type III secretion system that is encoded within Salmonella pathogenicity…”
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What Does CLARITY-BPA Mean for Canadians? by Rogers, Lindsay D.

“…Bisphenol A is an extremely high-volume chemical widely used in polycarbonate plastics, the linings of food and beverage tins, and shopping receipts. Canadians…”
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Phosphoproteomics--finally fulfilling the promise? by Rogers, Lindsay D, Foster, Leonard J

“…Networks of protein-protein and protein-metabolite interactions are commonly found in biological systems where signals must be passed from one location or…”
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LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification by Huesgen, Pitter F, Lange, Philipp F, Rogers, Lindsay D, Solis, Nestor, Eckhard, Ulrich, Kleifeld, Oded, Goulas, Theodoros, Gomis-Rüth, F Xavier, Overall, Christopher M

“…The Archaea metalloproteinase LysargiNase increases proteome coverage, identifies more C-terminal peptides from proteins and improves methylated peptide…”
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Identification of cognate host targets and specific ubiquitylation sites on the Salmonella SPI-1 effector SopB/SigD by Rogers, Lindsay D., Kristensen, Anders R., Boyle, Erin C., Robinson, Dale P., Ly, Richard T., Finlay, B. Brett, Foster, Leonard J.

“…Salmonella enterica is a bacterial pathogen responsible for enteritis and typhoid fever. Virulence is linked to two Salmonella pathogenicity islands (SPI-1 and…”
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Phosphoproteomic analysis of Salmonella-infected cells identifies key kinase regulators and SopB-dependent host phosphorylation events by Rogers, Lindsay D, Brown, Nat F, Fang, Yuan, Pelech, Steven, Foster, Leonard J

“…Salmonella enterica is a bacterial pathogen that causes gastroenteritis and typhoid fever. Virulence is achieved by two type III secretion systems that…”
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Quantitative Mass Spectrometry Catalogues Salmonella Pathogenicity Island-2 Effectors and Identifies Their Cognate Host Binding Partners by Auweter, Sigrid D., Bhavsar, Amit P., de Hoog, Carmen L., Li, Yuling, Chan, Y. Alina, van der Heijden, Joris, Lowden, Michael J., Coombes, Brian K., Rogers, Lindsay D., Stoynov, Nikolay, Foster, Leonard J., Finlay, B. Brett

“…Gram-negative bacterial pathogens have developed specialized secretion systems to transfer bacterial proteins directly into host cells. These bacterial…”
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An integrated global strategy for cell lysis, fractionation, enrichment and mass spectrometric analysis of phosphorylated peptides by Rogers, Lindsay D, Fang, Yuan, Foster, Leonard J

“…Recently, the field of phosphoproteomics has progressed to the point where thousands of protein phosphorylations can be analyzed simultaneously and used to…”
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A horizontally acquired transcription factor coordinates Salmonella adaptations to host microenvironments by Brown, Nat F, Rogers, Lindsay D, Sanderson, Kristy L, Gouw, Joost W, Hartland, Elizabeth L, Foster, Leonard J

“…The transcription factors HilA and SsrB activate expression of two type III secretion systems (T3SSs) and cognate effectors that reprogram host cell functions…”
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Contributions of proteomics to understanding phagosome maturation by Rogers, Lindsay D, Foster, Leonard J

“…In metazoans macrophage cells use phagocytosis, the process of engulfing large particles, to control the spread of pathogens in the body, to clear dead or…”
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A Horizontally Acquired Transcription Factor Coordinates italic toggle="yes">Salmonella /italic> Adaptations to Host Microenvironments by Nat F. Brown, Lindsay D. Rogers, Kristy L. Sanderson, Joost W. Gouw, Elizabeth L. Hartland, Leonard J. Foster

“…ABSTRACT The transcription factors HilA and SsrB activate expression of two type III secretion systems (T3SSs) and cognate effectors that reprogram host cell…”
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Long-term survival after the Fontan operation: Twenty years of experience at a single center by Downing, Tacy E., MD, Allen, Kiona Y., MD, Glatz, Andrew C., MD, MSCE, Rogers, Lindsay S., MD, Ravishankar, Chitra, MD, Rychik, Jack, MD, Faerber, Jennifer A., PhD, Fuller, Stephanie, MD, Montenegro, Lisa M., MD, Steven, James M., MD, Spray, Thomas L., MD, Nicolson, Susan C., MD, Gaynor, J. William, MD, Goldberg, David J., MD

“…Abstract Objective Existing studies of patients palliated with the Fontan operation are limited by heterogeneous patient populations and incomplete follow-up…”
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Effect of Fontan-Associated Morbidities on Survival With Intact Fontan Circulation by Allen, Kiona Y., MD, Downing, Tacy E., MD, Glatz, Andrew C., MD, MSCE, Rogers, Lindsay S., MD, Ravishankar, Chitra, MBBS, Rychik, Jack, MD, Fuller, Stephanie, MD, Montenegro, Lisa M., MD, Steven, James M., MD, Spray, Thomas L., MD, Nicolson, Susan C., MD, Gaynor, James William, MD, Goldberg, David J., MD

“…Although survival after the Fontan operation has improved, little is known about the burden of major medical morbidities associated with the modern total…”
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Reply by Rogers, Lindsay S., MD, Goldberg, David J., MD

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Mitral valve dysplasia syndrome: A unique form of left-sided heart disease by Rogers, Lindsay S., MD, Peterson, Amy L., MD, Gaynor, J. William, MD, Rome, Jonathan J., MD, Weinberg, Paul M., MD, Rychik, Jack, MD

“…Background Mitral valve dysplasia syndrome is a unique form of left-sided heart disease characterized by aortic outflow hypoplasia, dilated left ventricle,…”
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18 Years of the Fontan Operation at a Single Institution by Rogers, Lindsay S., MD, Glatz, Andrew C., MD, Ravishankar, Chitra, MD, Spray, Thomas L., MD, Nicolson, Susan C., MD, Rychik, Jack, MD, Rush, Christina Hayden, BSN, Gaynor, J. William, MD, Goldberg, David J., MD

“…Objectives The aim of this study was to evaluate Fontan peri-operative outcomes for 771 consecutive patients. Background Since the initial description by…”
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