Search Results - "Rogers, JT"

Redox-Active Metals, Oxidative Stress, and Alzheimer's Disease Pathology by HUANG, XUDONG, MOIR, ROBERT D., TANZI, RUDOLPH E., BUSH, ASHLEY I., ROGERS, JACK T.

“…: Considerable evidence is mounting that dyshomeostasis of the redox‐active biometals, Cu and Fe, and oxidative stress contribute to the neuropathology of…”
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An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript by Rogers, Jack T, Randall, Jeffrey D, Cahill, Catherine M, Eder, Paul S, Huang, Xudong, Gunshin, Hiromi, Leiter, Lorene, McPhee, Jay, Sarang, Satinder S, Utsuki, Tada, Greig, Nigel H, Lahiri, Debomoy K, Tanzi, Rudolph E, Bush, Ashley I, Giordano, Tony, Gullans, Steve R

“…Iron-responsive elements (IREs) are the RNA stem loops that control cellular iron homeostasis by regulating ferritin translation and transferrin receptor mRNA…”
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Metal and inflammatory targets for Alzheimer's disease by Rogers, Jack T, Lahiri, Debomoy K

“…Alzheimer's disease (AD) has become linked to inflammation and metal biology. Metals (copper, zinc and iron) and inflammatory cytokines are significant factors…”
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Ultrasound-guided thoracentesis: is it a safer method? by Jones, Phillip W, Moyers, J Phillip, Rogers, Jeffrey T, Rodriguez, R Michael, Lee, Y C Gary, Light, Richard W

“…The objectives of this study are as follows: (1) to determine the incidence of complications from thoracentesis performed under ultrasound guidance by…”
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Iron-dependent regulation of the divalent metal ion transporter by Gunshin, Hiromi, Allerson, Charles R., Polycarpou-Schwarz, Maria, Rofts, Andreas, Rogers, Jack T., Kishi, Fumio, Hentze, Matthias W., Rouault, Tracey A., Andrews, Nancy C., Hediger, Matthias A.

“…The first step in intestinal iron absorption is mediated by the H +-coupled Fe 2+ transporter called divalent cation transporter 1/divalent metal ion…”
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Characterization of branchial lead-calcium interaction in the freshwater rainbow trout Oncorhynchus mykiss by Rogers, Joseph T, Wood, Chris M

“…The mechanism of branchial lead uptake and interplay with Ca(2+) transport was investigated in the freshwater rainbow trout Oncorhynchus mykiss. Lead…”
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New Therapeutic Strategies and Drug Candidates for Neurodegenerative Diseases: p53 and TNF-α Inhibitors, and GLP-1 Receptor Agonists by GREIG, NIGEL H., MATTSON, MARK P., PERRY, TRACYANN, CHAN, SIC L., GIORDANO, TONY, SAMBAMURTI, KUMAR, ROGERS, JACK T., OVADIA, HAIM, LAHIRI, DEBOMOY K.

“…: Owing to improving preventative, diagnostic, and therapeutic measures for cardiovascular disease and a variety of cancers, the average ages of North…”
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Ionoregulatory disruption as the acute toxic mechanism for lead in the rainbow trout ( Oncorhynchus mykiss) by Rogers, J.T, Richards, J.G, Wood, C.M

“…The mechanism for acute toxicity of lead (Pb) in rainbow trout ( Oncorhynchus mykiss) was investigated at Pb concentrations close to the 96 h LC50 of 1.0 mg…”
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Intraspecific divergence of ionoregulatory physiology in the euryhaline teleost Fundulus heteroclitus: possible mechanisms of freshwater adaptation by Scott, Graham R, Rogers, Joseph T, Richards, Jeff G, Wood, Chris M, Schulte, Patricia M

“…We examined intraspecific variation in ionoregulatory physiology within euryhaline killifish, Fundulus heteroclitus, to understand possible mechanisms of…”
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Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis by Dedeoglu, Alpaslan, Cormier, Kerry, Payton, Sandra, Tseitlin, Katya A., Kremsky, Jonathan N., Lai, Li, Li, Xiaohua, Moir, Robert D., Tanzi, Rudolph E., Bush, Ashley I., Kowall, Neil W., Rogers, Jack T., Huang, Xudong

“…A growing body of evidence indicates that dysregulation of cerebral biometals (Fe, Cu, Zn) and their interactions with APP and Aβ amyloid may contribute to the…”
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Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation by Thomson, Andrew M, Rogers, Jack T, Leedman, Peter J

“…Iron plays a central role in the metabolism of all cells. This is evident by its major contribution to many diverse functions, such as DNA replication,…”
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Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences by Rogers, J T, Leiter, L M, McPhee, J, Cahill, C M, Zhan, S S, Potter, H, Nilsson, L N

“…The amyloid precursor protein (APP) has been associated with Alzheimer's disease (AD) because APP is processed into the beta-peptide that accumulates in…”
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Rationale for the development of cholinesterase inhibitors as anti-Alzheimer agents by Lahiri, D K, Rogers, J T, Greig, N H, Sambamurti, K

“…Alzheimer's disease (AD) is characterized by progressive dementia caused by the loss of the presynaptic markers of the cholinergic system in the brain areas…”
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Ferritin translation by interleukin-6: the role of sequences upstream of the start codons of the heavy and light subunit genes by Rogers, JT

“…Interleukin-1beta (IL-1beta) elevates H- and L-ferritin subunit synthesis in both human hepatoma cells (HepG2) and primary human umbilical vein endothelial…”
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Ferritin Translation by Interleukin-1 and Interleukin-6: The Role of Sequences Upstream of the Start Codons of the Heavy and Light Subunit Genes by Rogers, J.T.

“…Interleukin-1β (IL-1β) elevates H- and L-ferritin subunit synthesis in both human hepatoma cells (HepG2) and primary human umbilical vein endothelial cells…”
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Mechanisms behind Pb-induced disruption of Na+ and Cl- balance in rainbow trout (Oncorhynchus mykiss) by Rogers, Joseph T, Patel, Monika, Gilmour, Kathleen M, Wood, Chris M

“…The mechanism of Pb-induced disruption of Na(+) and Cl(-) balance was investigated in the freshwater rainbow trout (Oncorhynchus mykiss). Na(+) and Cl(-)…”
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The Integrated Role of Desferrioxamine and Phenserine Targeted to an Iron-Responsive Element in the APP-mRNA 5′-Untranslated Region by VENTI, AMANDA, GIORDANO, TONY, EDER, PAUL, BUSH, ASHLEY I., LAHIRI, DEBOMOY K., GREIG, NIGEL H., ROGERS, JACK T.

“…: The Alzheimer's amyloid precursor protein (APP) is the metalloprotein that is cleaved to generate the pathogenic Aβ peptide. We showed that iron closely…”
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Adenosine deaminase levels in nontuberculous lymphocytic pleural effusions by Lee, Y C, Rogers, J T, Rodriguez, R M, Miller, K D, Light, R W

“…Adenosine deaminase (ADA) can aid in the diagnosis of tuberculous pleural effusions, but false-positive findings from lymphocytic effusions have been reported…”
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Prevalence and clinical course of pleural effusions at 30 days after coronary artery and cardiac surgery by Light, Richard W, Rogers, Jeffrey T, Moyers, J Phillip, Lee, Y C Gary, Rodriguez, R Michael, Alford, Jr, William C, Ball, Stephen K, Burrus, George R, Coltharp, William H, Glassford, Jr, David M, Hoff, Steven J, Lea, 4th, John W, Nesbitt, Jonathan C, Petracek, Michael R, Starkey, Thomas D, Stoney, William S, Tedder, Mark

“…The present prospective study was designed to determine the prevalence of pleural effusion at approximately 28 days after cardiac surgery and their subsequent…”
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The Acute Box cis-Element in Human Heavy Ferritin mRNA 5′-Untranslated Region Is a Unique Translation Enhancer That Binds Poly(C)-binding Proteins by Thomson, Andrew M., Cahill, Catherine M., Cho, Hyun-Hee, Kassachau, Kristin D., Epis, Michael R., Bridges, Kenneth R., Leedman, Peter J., Rogers, Jack T.

“…Intracellular levels of the light (L) and heavy (H) ferritin subunits are regulated by iron at the level of message translation via a modulated interaction…”
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