Search Results - "Roger, S D"

Extended administration of erythropoiesis-stimulating agents for optimising the management of renal anaemia: what is the evidence? by Roger, S D

“…Erythropoiesis-stimulating agents (ESAs) have transformed the management of anaemia in patients with chronic kidney disease (CKD), reducing transfusion…”
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Beware what lies beneath: a case of a gigantic cutaneous squamous cell carcinoma by Dickison, P., Roger, S. D., Howard, V., Smith, S. D.

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Biosimilars: it's not as simple as cost alone by Roger, S. D., Goldsmith, D.

“…Background:  Biosimilars or follow‐on biologics (FoB) are biopharmaceuticals that, unlike small molecule generic products, are copies of larger, much more…”
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Contribution of anaemia to progression of renal disease: a debate by Rossert, J. A., McClellan, W. M., Roger, S. D., Verbeelen, D. L., Hörl, W. H.

“…It is hypothesized that anaemia contributes to the progression of renal disease via hypoxia and oxidative stress. These effects may stimulate the production of…”
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Cardiovascular risk reduction in hypertension: angiotensin-converting enzyme inhibitors, angiotensin receptor blockers. Where are we up to? by Sindone, A., Erlich, J., Lee, C., Newman, H., Suranyi, M., Roger, S. D.

“…Previously, management of hypertension has concentrated on lowering elevated blood pressure. However, the target has shifted to reducing absolute…”
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Effects of erythropoietin on blood pressure by Raine, A E, Roger, S D

“…Increased blood pressure (BP) has been the most commonly reported side effect in trials of treatment of the anemia of chronic renal failure with recombinant…”
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Clinical correlates and consequences of anemia in a broad spectrum of patients with heart failure : Results of the candesartan in heart failure: assessment of reduction in mortality and morbidity (CHARM) program by O'MEARA, Eileen, CLAYTON, Tim, OLOFSSON, Bertil, MICHELSON, Eric L, POCOCK, Stuart, YUSUF, Salim, SWEDBERG, Karl, PFEFFER, Marc A, MCENTEGART, Margaret B, MCMURRAY, John J. V, LANG, Chim C, ROGER, Simon D, YOUNG, James B, SOLOMON, Scott D, GRANGER, Christopher B, ÖSTERGREN, Jan

“…We wished to determine the prevalence of, potential mechanistic associations of, and clinical outcomes related to anemia in patients with heart failure and a…”
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Research degrees for medical graduates by Roger, S. D.

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Test performance characteristics of quantitative nucleic acid testing for polyomaviruses in kidney and kidney-pancreas transplant recipients by Myint, T.M.M., Turner, R.M., Craig, J.C., Cross, N.B., Kable, K., Nankivell, B.J., Chapman, J.R., Webster, A.C., O'Connell, P., Dwyer, D.E., Jeoffreys, N., Roger, S.D., Wong, G.

“…Screening for polyoma BK virus (BK) using nucleic testing (NAT) is recommended for kidney and kidney‐pancreas transplant recipients, but the performance…”
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Possible relation between restless legs and anaemia in renal dialysis patients by Roger, S D, Harris, D C, Stewart, J H

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What is the value of measuring renal parenchymal thickness before renal biopsy? by Roger, S D, Beale, A M, Cattell, W R, Webb, J A

“…Reduced renal length is widely used to diagnose chronicity in patients with renal impairment. A length of 9 cm or less measured ultrasonographically is…”
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Autonomic dysfunction and the development of hypertension in patients treated with recombinant human erythropoietin (r-HuEPO) by Roger, S D, Baker, L R, Raine, A E

“…Hypertension is the most common complication of r-HuEPO therapy in dialysis patients. The aim of this study was to test the hypothesis that hypertension…”
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Enhanced platelet reactivity with erythropoietin but not following transfusion in dialysis patients by Roger, S D, Piper, J, Tucker, B, Raine, A E, Baker, L R, Kovacs, I B

“…Although the haemostatic defects that occur in uraemia are complex, a major factor is the anaemia of renal failure. This may now be corrected by recombinant…”
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Effects of oxygen breathing and erythropoietin on hypoxic vasodilation in uremic anemia by Roger, Simon D., Grasty, Marianne S., Baker, Laurence R.I., Raine, Anthony E.G.

“…Effects of oxygen breathing and erythropoietin on hypoxic vasodilation in uremic anemia. Loss of hypoxic vasodilation has been proposed as a causative factor…”
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Modulation of platelet cytosolic calcium during erythropoietin therapy in uraemia by Fluck, R J, Roger, S D, McMahon, A C, Raine, A E

“…Erythropoietin therapy for uraemic anaemia is associated with a high rate of hypertensive and thrombotic complications. The mechanism is unknown, but a change…”
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FIND-CKD: a randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia by Macdougall, Iain C, Bock, Andreas H, Carrera, Fernando, Eckardt, Kai-Uwe, Gaillard, Carlo, Van Wyck, David, Roubert, Bernard, Nolen, Jacqueline G, Roger, Simon D

“…The optimal iron therapy regimen in patients with non-dialysis-dependent chronic kidney disease (CKD) is unknown. Ferinject® assessment in patients with Iron…”
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Improvement in anaemia following renal transplantation but not after erythropoietin therapy in a patient with sickle-cell disease by Thuraisingham, R C, Roger, S D, Macdougall, I C, Cavill, I, Stephens, A D, Baker, L R, Raine, A E

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Assessment of the bioequivalence of a generic cyclosporine A by a randomized controlled trial in stable renal recipients by HIBBERD, Adrian D, TREVILLIAN, Paul R, ROGER, Simon D, WLODARCZYK, John H, STEIN, Ann M, BOHRINGER, Elizabeth G, MILSON-HAWKE, Sally M

“…The aim of this study was to determine the bioequivalence of Cysporin, a generic cyclosporine A, compared with Neoral in stable renal transplant recipients…”
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Desferrioxamine enhances the haemopoietic response to erythropoietin, but adverse events are common by Roger, S D, Stewart, J H, Harris, D C

“…To determine whether the chelation of aluminium enhances the haemopoietic response to recombinant human erythropoietin (r-HuEPO), desferrioxamine (DFO) at a…”
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Recombinant erythropoietin increases blood pressure in experimental hypertension and uraemia without change in vascular cytosolic calcium by Roger, S D, Fluck, R J, McMahon, A C, Raine, A E

“…The mechanism of erythropoietin-induced hypertension in dialysis patients is unclear. Intracellular calcium ([Ca2+]i) may be altered in both hypertension and…”
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