Search Results - "Rogalski, Sherri L."
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Eicosanoids Inhibit the G-protein-gated Inwardly Rectifying Potassium Channel (Kir3) at the Na+/PIP2 Gating Site
Published in The Journal of biological chemistry (04-05-2001)“…We previously showed that activation of the human endothelin A receptor (HETAR) by endothelin-1 (Et-1) selectively inhibits the response to mu opioid receptor…”
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TrkB Activation by Brain-derived Neurotrophic Factor Inhibits the G Protein-gated Inward Rectifier Kir3 by Tyrosine Phosphorylation of the Channel
Published in The Journal of biological chemistry (18-08-2000)“…G protein-activated inwardly rectifying potassium channels (Kir3) are widely expressed throughout the brain, and regulation of their activity modifies neuronal…”
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Predicting ADME properties and side effects: the BioPrint approach
Published in Current opinion in drug discovery & development (01-07-2003)“…Computational methods are increasingly used to streamline and enhance the lead discovery and optimization process. However, accurate prediction of absorption,…”
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N-terminal Tyrosine Residues within the Potassium Channel Kir3 Modulate GTPase Activity of Gαi
Published in The Journal of biological chemistry (06-09-2002)“…trkB activation results in tyrosine phosphorylation of N-terminal Kir3 residues, decreasing channel activation. To determine the mechanism of this effect, we…”
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Activation of the Endothelin Receptor Inhibits the G Protein‐Coupled Inwardly Rectifying Potassium Channel by a Phospholipase A 2 ‐Mediated Mechanism
Published in Journal of neurochemistry (01-04-1999)“…To develop a malleable system to model the well‐described, physiological interactions between G q/11 ‐coupled receptor and G i/o ‐coupled receptor signaling,…”
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N-terminal Tyrosine Residues within the Potassium Channel Kir3 Modulate GTPase Activity of Gαi
Published in The Journal of biological chemistry (06-09-2002)“…trkB activation results in tyrosine phosphorylation of N-terminal Kir3 residues, decreasing channel activation. To determine the mechanism of this effect, we…”
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7
N-terminal tyrosine residues within the potassium channel Kir3 modulate GTPase activity of Galphai
Published in The Journal of biological chemistry (06-09-2002)“…trkB activation results in tyrosine phosphorylation of N-terminal Kir3 residues, decreasing channel activation. To determine the mechanism of this effect, we…”
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8
Activation of the Endothelin Receptor Inhibits the G Protein‐Coupled Inwardly Rectifying Potassium Channel by a Phospholipase A2‐Mediated Mechanism
Published in Journal of neurochemistry (01-04-1999)“…: To develop a malleable system to model the well‐described, physiological interactions between Gq/11‐coupled receptor and Gi/o‐coupled receptor signaling, we…”
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