Search Results - "Roga, Stephane"

IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G by Lefrançais, Emma, Roga, Stephane, Gautier, Violette, Gonzalez-de-Peredo, Anne, Monsarrat, Bernard, Girard, Jean-Philippe, Cayrol, Corinne

“…lnterleukin-33 (IL-33) (NF-HEV) is a chromatin-associated nuclear cytokine from the IL-1 family, which has been linked to important diseases, including asthma,…”
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Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells by Lefrançais, Emma, Duval, Anais, Mirey, Emilie, Roga, Stéphane, Espinosa, Eric, Cayrol, Corinne, Girard, Jean-Philippe

“…Interleukin-33 (IL-33) is an alarmin cytokine from the IL-1 family. IL-33 activates many immune cell types expressing the interleukin 1 receptor-like 1…”
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Environmental allergens induce allergic inflammation through proteolytic maturation of IL-33 by Cayrol, Corinne, Duval, Anais, Schmitt, Pauline, Roga, Stephane, Camus, Mylène, Stella, Alexandre, Burlet-Schiltz, Odile, Gonzalez-de-Peredo, Anne, Girard, Jean-Philippe

“…Allergic inflammation has crucial roles in allergic diseases such as asthma. It is therefore important to understand why and how the immune system responds to…”
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TL1A is an epithelial alarmin that cooperates with IL-33 for initiation of allergic airway inflammation by Schmitt, Pauline, Duval, Anais, Camus, Mylène, Lefrançais, Emma, Roga, Stéphane, Dedieu, Cécile, Ortega, Nathalie, Bellard, Elisabeth, Mirey, Emilie, Mouton-Barbosa, Emmanuelle, Burlet-Schiltz, Odile, Gonzalez-de-Peredo, Anne, Cayrol, Corinne, Girard, Jean-Philippe

“…Epithelium-derived cytokines or alarmins, such as interleukin-33 (IL-33) and thymic stromal lymphopoietin (TSLP), are major players in type 2 immunity and…”
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Extracellular IL-33 cytokine, but not endogenous nuclear IL-33, regulates protein expression in endothelial cells by Gautier, Violette, Cayrol, Corinne, Farache, Dorian, Roga, Stéphane, Monsarrat, Bernard, Burlet-Schiltz, Odile, Gonzalez de Peredo, Anne, Girard, Jean-Philippe

“…IL-33 is a nuclear cytokine from the IL-1 family that plays important roles in health and disease. Extracellular IL-33 activates a growing number of target…”
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In Vivo Expansion of Activated Foxp3+ Regulatory T Cells and Establishment of a Type 2 Immune Response upon IL-33 Treatment Protect against Experimental Arthritis by Biton, Jérôme, Khaleghparast Athari, Sara, Thiolat, Allan, Santinon, François, Lemeiter, Delphine, Hervé, Roxane, Delavallée, Laure, Levescot, Anais, Roga, Stéphane, Decker, Patrice, Girard, Jean-Philippe, Herbelin, André, Boissier, Marie-Christophe, Bessis, Natacha

“…IL-33 is strongly involved in several inflammatory and autoimmune disorders with both pro- and anti-inflammatory properties. However, its contribution to…”
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pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-γ production by Bourgeois, Elvire, Van, Linh Pham, Samson, Michel, Diem, Séverine, Barra, Anne, Roga, Stéphane, Gombert, Jean-Marc, Schneider, Elke, Dy, Michel, Gourdy, Pierre, Girard, Jean-Philippe, Herbelin, André

“…IL-33 has recently been identified as a cytokine endowed with pro-Th2 functions, raising the question of its effect on invariant natural killer T cell (iNKT),…”
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Targeting androgen signaling in ILC2s protects from IL-33–driven lung inflammation, independently of KLRG1 by Blanquart, Eve, Mandonnet, Audrey, Mars, Marion, Cenac, Claire, Anesi, Nina, Mercier, Pascale, Audouard, Christophe, Roga, Stephane, Serrano de Almeida, Gilberto, Bevan, Charlotte L., Girard, Jean-Philippe, Pelletier, Lucette, Laffont, Sophie, Guéry, Jean-Charles

“…Allergic asthma is more severe and frequent in women than in men. In male mice, androgens negatively control group 2 innate lymphoid cell (ILC2) development…”
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TCRV gamma 9 gamma delta T Cell Response to IL-33: A CD4 T Cell-Dependent Mechanism by Duault, Caroline, Franchini, Don Marc, Familliades, Julien, Cayrol, Corinne, Roga, Stephane, Girard, Jean-Philippe, Fournie, Jean-Jacques, Poupot, Mary

“…The availability of specific stimuli to induce the anticancer cytotoxicity of human TCRV gamma 9-expressing T lymphocytes has allowed the development of gamma…”
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CS05-4. Inflammatory Proteases Cleave and Activate IL-33, a novel alarmin from the IL-1 Family by Cayrol, Corinne, Lefrancais, Emma, Roga, Stephane, Girard, Jean-Philippe

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Exogenously Added Fibroblast Growth Factor 2 (FGF-2) to NIH3T3 Cells Interacts with Nuclear Ribosomal S6 Kinase 2 (RSK2) in a Cell Cycle-dependent Manner by Soulet, Fabienne, Bailly, Karine, Roga, Stéphane, Lavigne, Anne-Claire, Amalric, François, Bouche, Gérard

“…Fibroblast growth factor 2 (FGF-2) has been detected in the nuclei of many tissues and cell lines. Here we demonstrate that FGF-2 added exogenously to NIH3T3…”
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IL-9high GATA3low ILC2s are potent inducers of allergic airway inflammation by Schmitt, Pauline, Duval, Anaïs, Roga, Stéphane, Camus, Mylène, Burlet-Schiltz, Odile, Gonzalez-de-Peredo, Anne, Cayrol, Corinne, Girard, Jean-Philippe

“…IL-9 is key driver of chronic and allergic inflammation at mucosal surfaces, with important roles in the activation and survival of mast cells and type 2…”
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IL‐33‐expanded human Vγ9Vδ2 T cells have anti‐lymphoma effect in a mouse tumor model by Duault, Caroline, Betous, Delphine, Bezombes, Christine, Roga, Stéphane, Cayrol, Corinne, Girard, Jean‐Philippe, Fournié, Jean‐Jacques, Poupot, Mary

“…From several years, the anticancer effects of Vγ9 T lymphocytes make these cells good candidates for cancer immunotherapies. However, the proved efficacy of…”
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IL-33-expanded human V[gamma]9V[delta]2 Tￂ cells have anti-lymphoma effect in a mouse tumor model by Duault, Caroline, Betous, Delphine, Bezombes, Christine, Roga, Stéphane, Cayrol, Corinne, Girard, Jean-Philippe, Fournie, Jean-Jacques, Poupot, Mary

“…From several years, the anticancer effects of V[gamma]9 T lymphocytes make these cells good candidates for cancer immunotherapies. However, the proved efficacy…”
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TCRVγ9 γδ T Cell Response to IL-33: A CD4 T Cell-Dependent Mechanism by Duault, Caroline, Franchini, Don Marc, Familliades, Julien, Cayrol, Corinne, Roga, Stéphane, Girard, Jean-Philippe, Fournié, Jean-Jacques, Poupot, Mary

“…The availability of specific stimuli to induce the anticancer cytotoxicity of human TCRVγ9-expressing T lymphocytes has allowed the development of γδ T…”
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IL-33 is processed into mature bioactive forms by neutrophil serine proteases (172.26) by Lefrançais, Emma, Roga, Stéphane, Gautier, Violette, Gonzales de Peredo, Anne, Monsarrat, Bernard, Girard, Jean Philippe, Cayrol, Corinne

“…IL-33 is a chromatin-associated nuclear cytokine from the IL-1 family, which has been linked to many inflammatory diseases. IL-33 signals through the receptor…”
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Fibroblast Growth Factor-2 Interacts with Free Ribosomal Protein S19 by Soulet, Fabienne, Al Saati, Talal, Roga, Stéphane, Amalric, François, Bouche, Gérard

“…Exogenous FGF-2 added to cells is internalized and part of it translocates to the nucleus of the cells. To get a better understanding of the FGF-2-induced…”
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The pro-Th2 cytokine IL-33 directly interacts with invariant NKT and NK cells to induce IFN-gamma production by Bourgeois, Elvire, Van, Linh Pham, Samson, Michel, Diem, Séverine, Barra, Anne, Roga, Stéphane, Gombert, Jean-Marc, Schneider, Elke, Dy, Michel, Gourdy, Pierre, Girard, Jean-Philippe, Herbelin, André

“…IL-33 has recently been identified as a cytokine endowed with pro-Th2 functions, raising the question of its effect on invariant natural killer T cell (iNKT),…”
Get full text

Exogenously Added Fibroblast Growth Factor 2 (FGF-2) to NIH3T3 CellsInteracts with Nuclear Ribosomal S6 Kinase 2 (RSK2) in a Cell Cycle-dependentManner by Soulet, Fabienne, Bailly, Karine, Roga, Stéphane, Lavigne, Anne-Claire, Amalric, François, Bouche, Gérard

“…Fibroblast growth factor 2 (FGF-2) has been detected in the nuclei of manytissues and cell lines. Here we demonstrate that FGF-2 added exogenously toNIH3T3…”
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Exogenously Added Fibroblast Growth Factor 2 (FGF-2) to NIH3T3 Cells Interacts with Nuclear Ribosomal S6 Kinase 2 (RSK2) in a Cell Cycle-dependentManner by Soulet, Fabienne, Bailly, Karine, Roga, Stéphane, Lavigne, Anne-Claire, Amalric, François, Bouche, Gérard

“…Fibroblast growth factor 2 (FGF-2) has been detected in the nuclei of many tissues and cell lines. Here we demonstrate that FGF-2 added exogenously to NIH3T3…”
Get full text