Search Results - "Roeyen, Geert"

Pancreaticojejunostomy versus pancreaticogastrostomy reconstruction after pancreaticoduodenectomy for pancreatic or periampullary tumours: a multicentre randomised trial by Topal, Baki, Prof, Fieuws, Steffen, PhD, Aerts, Raymond, MD, Weerts, Joseph, MD, Feryn, Tom, MD, Roeyen, Geert, MD, Bertrand, Claude, MD, Hubert, Catherine, MD, Janssens, Marc, MD, Closset, Jean, MD

“…Summary Background Postoperative pancreatic fistula is the leading cause of death and morbidity after pancreaticoduodenectomy. However, the best reconstruction…”
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The art of obtaining a high yield of cell-free DNA from urine by Augustus, Elien, Van Casteren, Kaat, Sorber, Laure, van Dam, Peter, Roeyen, Geert, Peeters, Marc, Vorsters, Alex, Wouters, An, Raskin, Jo, Rolfo, Christian, Zwaenepoel, Karen, Pauwels, Patrick

“…Although liquid biopsies offer many advantages over tissue biopsies, they are not yet standard practice. An important reason for the lack of implementation is…”
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Cancer-Associated Fibroblasts as a Common Orchestrator of Therapy Resistance in Lung and Pancreatic Cancer by Domen, Andreas, Quatannens, Delphine, Zanivan, Sara, Deben, Christophe, Van Audenaerde, Jonas, Smits, Evelien, Wouters, An, Lardon, Filip, Roeyen, Geert, Verhoeven, Yannick, Janssens, Annelies, Vandamme, Timon, van Dam, Peter, Peeters, Marc, Prenen, Hans

“…Cancer arises from mutations accruing within cancer cells, but the tumor microenvironment (TME) is believed to be a major, often neglected, factor involved in…”
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Auranofin repurposing for lung and pancreatic cancer: low CA12 expression as a marker of sensitivity in patient-derived organoids, with potentiated efficacy by AKT inhibition by Deben, Christophe, Boullosa, Laurie Freire, Fortes, Felicia Rodrigues, De La Hoz, Edgar Cardenas, Le Compte, Maxim, Seghers, Sofie, Peeters, Marc, Vanlanduit, Steve, Lin, Abraham, Dijkstra, Krijn K, Van Schil, Paul, Hendriks, Jeroen M H, Prenen, Hans, Roeyen, Geert, Lardon, Filip, Smits, Evelien

“…This study explores the repurposing of Auranofin (AF), an anti-rheumatic drug, for treating non-small cell lung cancer (NSCLC) adenocarcinoma and pancreatic…”
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The impact of pancreaticoduodenectomy on endocrine and exocrine pancreatic function: A prospective cohort study based on pre- and postoperative function tests by Roeyen, Geert, Jansen, Miet, Hartman, Vera, Chapelle, Thiery, Bracke, Bart, Ysebaert, Dirk, De Block, Christophe

“…Studies reporting on function after pancreatic surgery are frequently based on diabetes history, fasting glycemia or random glycemia. The aim of this study was…”
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Cell-Free DNA From Metastatic Pancreatic Neuroendocrine Tumor Patients Contains Tumor-Specific Mutations and Copy Number Variations by Boons, Gitta, Vandamme, Timon, Peeters, Marc, Beyens, Matthias, Driessen, Ann, Janssens, Katrien, Zwaenepoel, Karen, Roeyen, Geert, Van Camp, Guy, Op de Beeck, Ken

“…Detection of tumor-specific alterations in cell-free DNA (cfDNA) has proven valuable as a liquid biopsy for several types of cancer. So far, use of cfDNA…”
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Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer by Le Compte, Maxim, De La Hoz, Edgar Cardenas, Peeters, Sofía, Fortes, Felicia Rodrigues, Hermans, Christophe, Domen, Andreas, Smits, Evelien, Lardon, Filip, Vandamme, Timon, Lin, Abraham, Vanlanduit, Steve, Roeyen, Geert, Van Laere, Steven, Prenen, Hans, Peeters, Marc, Deben, Christophe

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal diseases, characterized by a treatment-resistant and invasive nature. In line with these…”
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A Comparison of Cell-Free DNA Isolation Kits by Sorber, Laure, Zwaenepoel, Karen, Deschoolmeester, Vanessa, Roeyen, Geert, Lardon, Filip, Rolfo, Christian, Pauwels, Patrick

“…The analysis of cell-free DNA (cfDNA) as a sensitive biomarker for cancer diagnosis and monitoring has resulted in a need for efficient and standardized cfDNA…”
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Novel combination immunotherapy for pancreatic cancer: potent anti‐tumor effects with CD40 agonist and interleukin‐15 treatment by Van Audenaerde, Jonas RM, Marcq, Elly, Scheidt, Bianca, Davey, Ashleigh S, Oliver, Amanda J, De Waele, Jorrit, Quatannens, Delphine, Van Loenhout, Jinthe, Pauwels, Patrick, Roeyen, Geert, Lardon, Filip, Slaney, Clare Y, Peeters, Marc, Kershaw, Michael H, Darcy, Phillip K, Smits, Evelien LJM

“…Objectives With the poorest 5‐year survival of all cancers, improving treatment for pancreatic cancer is one of the biggest challenges in cancer research. We…”
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453 Novel combination immunotherapy for boosting and priming immune responses in pancreatic cancer: strong anti-tumour effects with interleukin-15 and CD40 agonist treatment by Audenaerde, Jonas Van, Marcq, Elly, Scheidt, Bianca von, Davey, Ashleigh, Oliver, Amanda, Waele, Jorrit De, Quatannens, Delphine, Loenhout, Jinthe Van, Pauwels, Patrick, Roeyen, Geert, Lardon, Filip, Slaney, Clare, Peeters, Marc, Kershaw, Michael, Darcy, Phillip, Smits, Evelien

“…BackgroundWith the poorest 5-year survival of all cancers, improving treatment for pancreatic cancer is one of the biggest challenges in cancer research. In…”
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A Comparison of Cell-Free DNA Isolation Kits: Isolation and Quantification of Cell-Free DNA in Plasma by Sorber, Laure, Zwaenepoel, Karen, Deschoolmeester, Vanessa, Roeyen, Geert, Lardon, Filip, Rolfo, Christian, Pauwels, Patrick

“…The analysis of cell-free DNA (cfDNA) as a sensitive biomarker for cancer diagnosis and monitoring has resulted in a need for efficient and standardized cfDNA…”
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A plea for more practical and clinically applicable criteria defining type 3c diabetes by Roeyen, Geert, De Block, Christophe

“…[...]are these newly diagnosed DM patients suffering from type 3c DM as defined by World Health Organization or American Diabetes Association [8,9]? Because…”
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Targeting hedgehog signaling in pancreatic ductal adenocarcinoma by Quatannens, Delphine, Verhoeven, Yannick, Van Dam, Peter, Lardon, Filip, Prenen, Hans, Roeyen, Geert, Peeters, Marc, Smits, Evelien L.J., Van Audenaerde, Jonas

“…Pancreatic ductal adenocarcinoma (PDAC) remains a leading cause of cancer related death. The urgent need for effective therapies is highlighted by the lack of…”
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Future remnant liver function estimated by combining liver volumetry on magnetic resonance imaging with total liver function on (99m)Tc-mebrofenin hepatobiliary scintigraphy: can this tool predict post-hepatectomy liver failure? by Chapelle, Thiery, Op De Beeck, Bart, Huyghe, Ivan, Francque, Sven, Driessen, Ann, Roeyen, Geert, Ysebaert, Dirk, De Greef, Kathleen

“…Posthepatectomy liver failure (PHLF) is a major complication after hepatectomy with a high mortality rate and is likely to happen in insufficient liver…”
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Circulating Cell-Free DNA and RNA Analysis as Liquid Biopsy: Optimal Centrifugation Protocol by Sorber, Laure, Zwaenepoel, Karen, Jacobs, Julie, De Winne, Koen, Goethals, Sofie, Reclusa, Pablo, Van Casteren, Kaat, Augustus, Elien, Lardon, Filip, Roeyen, Geert, Peeters, Marc, Van Meerbeeck, Jan, Rolfo, Christian, Pauwels, Patrick

“…The combined analysis of circulating cell-free (tumor) DNA (cfDNA/ctDNA) and circulating cell-free (tumor) RNA (cfRNA/ctRNA) shows great promise in determining…”
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Longitudinal Copy-Number Alteration Analysis in Plasma Cell-Free DNA of Neuroendocrine Neoplasms is a Novel Specific Biomarker for Diagnosis, Prognosis, and Follow-up by Boons, Gitta, Vandamme, Timon, Mariën, Laura, Lybaert, Willem, Roeyen, Geert, Rondou, Tim, Papadimitriou, Konstantinos, Janssens, Katrien, Op de Beeck, Bart, Simoens, Marc, Demey, Wim, Dero, Isabel, Van Camp, Guy, Peeters, Marc, Op de Beeck, Ken

“…As noninvasive biomarkers are an important unmet need for neuroendocrine neoplasms (NEN), biomarker potential of genome-wide molecular profiling of plasma…”
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Copy number alterations in plasma cell-free DNA from metastatic gastroenteropancreatic neuroendocrine neoplasms by Boons, Gitta, Vandamme, Timon, Lybaert, Willem, Roeyen, Geert, Rondou, Tim, Papadimitriou, Konstantinos, Janssens, Katrien, Demey, Wim, Dero, Isabel, Van Camp, Guy, Peeters, Marc, Op de Beeck, Ken

“…Abstract only 372 Background: Recent studies, including our proof-of-concept study, demonstrated the possibility to detect tumor-derived molecular alterations…”
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Prognostic and Predictive Biomarkers in Non-Small Cell Lung Cancer Patients on Immunotherapy-The Role of Liquid Biopsy in Unraveling the Puzzle by Augustus, Elien, Zwaenepoel, Karen, Siozopoulou, Vasiliki, Raskin, Jo, Jordaens, Stephanie, Baggerman, Geert, Sorber, Laure, Roeyen, Geert, Peeters, Marc, Pauwels, Patrick

“…In the last decade, immunotherapy has been one of the most important advances in the non-small cell lung cancer (NSCLC) treatment landscape. Nevertheless, only…”
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Natural killer cells and their therapeutic role in pancreatic cancer: A systematic review by Van Audenaerde, Jonas R.M., Roeyen, Geert, Darcy, Phillip K., Kershaw, Michael H., Peeters, M., Smits, Evelien L.J.

“…Pancreatic cancer is among the three deadliest cancers worldwide with the lowest 5-year survival of all cancers. Despite all efforts, therapeutic improvements…”
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Tailoring the Use of Central Pancreatectomy Through Prediction Models for Major Morbidity and Postoperative Diabetes: International Retrospective Multicenter Study by van Bodegraven, Eduard Antonie, Lof, Sanne, Jones, Leia, Aussilhou, Béatrice, Yong, Gao, Jishu, Wei, Klotz, Rosa, Rocha-Castellanos, Dario Missael, Matsumato, Ippei, de Ponthaud, Charles, Tanaka, Kimitaka, Biesel, Esther, Kauffmann, Emmanuele, Dumitrascu, Traian, Nagakawa, Yuichi, Martí-Cruchaga, Pablo, Roeyen, Geert, Zerbi, Alessandro, Goetz, Mara, de Meijer, Vincent, Pessaux, Patrick, Ignatavicius, Povilas, Demir, Ihsan, Giuffrida, Mario, Tingstedt, Bobby, Marino, Marco Vito, Mastoridis, Sotiris, Brunner, Maximilian, Mora-Oliver, Isabel, Bortolato, Cecilia, Gulla, Aisté, Apers, Thomas, Hermand, Hélène, Mitsuka, Yusuke, Popescu, Irinel, Boggi, Ugo, Wittel, Uwe, Hirano, Satoshi, Gaujoux, Sébastien, Kamei, Keiko, Fernández-Del Castillo, Carlos, Hackert, Thilo, Kuirong, Jiang, Yi, Miao, Sauvanet, Alain, Besselink, Marc, Abu Hilal, Mohammad, Dokmak, Safi

“…To develop a prediction model for major morbidity and endocrine dysfunction after CP which could help in tailoring the use of this procedure. Central…”
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