Search Results - "Roetschke, Hanna P."

Protein degradation by human 20S proteasomes elucidates the interplay between peptide hydrolysis and splicing by Soh, Wai Tuck, Roetschke, Hanna P., Cormican, John A., Teo, Bei Fang, Chiam, Nyet Cheng, Raabe, Monika, Pflanz, Ralf, Henneberg, Fabian, Becker, Stefan, Chari, Ashwin, Liu, Haiyan, Urlaub, Henning, Liepe, Juliane, Mishto, Michele

“…If and how proteasomes catalyze not only peptide hydrolysis but also peptide splicing is an open question that has divided the scientific community. The debate…”
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InvitroSPI and a large database of proteasome-generated spliced and non-spliced peptides by Roetschke, Hanna P., Rodriguez-Hernandez, Guillermo, Cormican, John A., Yang, Xiaoping, Lynham, Steven, Mishto, Michele, Liepe, Juliane

“…Noncanonical epitopes presented by Human Leucocyte Antigen class I (HLA-I) complexes to CD8 + T cells attracted the spotlight in the research of novel…”
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A roadmap for ribosome assembly in human mitochondria by Lavdovskaia, Elena, Hanitsch, Elisa, Linden, Andreas, Pašen, Martin, Challa, Venkatapathi, Horokhovskyi, Yehor, Roetschke, Hanna P, Nadler, Franziska, Welp, Luisa, Steube, Emely, Heinrichs, Marleen, Mai, Mandy Mong-Quyen, Urlaub, Henning, Liepe, Juliane, Richter-Dennerlein, Ricarda

“…Mitochondria contain dedicated ribosomes (mitoribosomes), which synthesize the mitochondrial-encoded core components of the oxidative phosphorylation…”
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Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes by Specht, Gerd, Roetschke, Hanna P., Mansurkhodzhaev, Artem, Henklein, Petra, Textoris-Taube, Kathrin, Urlaub, Henning, Mishto, Michele, Liepe, Juliane

“…Proteasomes are the main producers of antigenic peptides presented to CD8 + T cells. They can cut proteins and release their fragments or recombine…”
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