Search Results - "Roesel, Charles"

Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets by Vinayagam, Arunachalam, Gibson, Travis E., Lee, Ho-Joon, Yilmazel, Bahar, Roesel, Charles, Hu, Yanhui, Kwon, Young, Sharma, Amitabh, Liu, Yang-Yu, Perrimon, Norbert, Barabási, Albert-László

“…The protein–protein interaction (PPI) network is crucial for cellular information processing and decision-making. With suitable inputs, PPI networks drive the…”
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Genomic signatures of disease resistance in endangered staghorn corals by Vollmer, Steven V., Selwyn, Jason D., Despard, Brecia A., Roesel, Charles L.

“…White band disease (WBD) has caused unprecedented declines in the Caribbean Acropora corals, which are now listed as critically endangered species. Highly…”
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Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9 by Ren, Xingjie, Sun, Jin, Housden, Benjamin E., Hu, Yanhui, Roesel, Charles, Lin, Shuailiang, Liu, Lu-Ping, Yang, Zhihao, Mao, Decai, Sun, Lingzhu, Wu, Qujie, Jie, Jun-Yuan, Xi, Jianzhong, Mohr, Stephanie E., Xu, Jiang, Perrimon, Norbert, Ni, Jian-Quan

“…The ability to engineer genomes in a specific, systematic, and cost-effective way is critical for functional genomic studies. Recent advances using the…”
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Differential gene expression analysis of symbiotic and aposymbiotic Exaiptasia anemones under immune challenge with Vibrio coralliilyticus by Roesel, Charles L., Vollmer, Steven V.

“…Anthozoans are a class of Cnidarians that includes scleractinian corals, anemones, and their relatives. Despite a global rise in disease epizootics impacting…”
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Protein complex-based analysis framework for high-throughput data sets by Vinayagam, Arunachalam, Hu, Yanhui, Kulkarni, Meghana, Roesel, Charles, Sopko, Richelle, Mohr, Stephanie E, Perrimon, Norbert

“…Analysis of high-throughput data increasingly relies on pathway annotation and functional information derived from Gene Ontology. This approach has…”
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Transcriptomics reveals specific molecular mechanisms underlying transgenerational immunity in Manduca sexta by Roesel, Charles L., Rosengaus, Rebeca B., Smith, Wendy, Vollmer, Steven V.

“…The traditional view of innate immunity in insects is that every exposure to a pathogen triggers an identical and appropriate immune response and that prior…”
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UP-TORR: online tool for accurate and Up-to-Date annotation of RNAi Reagents by Hu, Yanhui, Roesel, Charles, Flockhart, Ian, Perkins, Lizabeth, Perrimon, Norbert, Mohr, Stephanie E

“…RNA interference (RNAi) is a widely adopted tool for loss-of-function studies but RNAi results only have biological relevance if the reagents are appropriately…”
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Integrating protein-protein interaction networks with phenotypes reveals signs of interactions by Vinayagam, Arunachalam, Zirin, Jonathan, Roesel, Charles, Hu, Yanhui, Yilmazel, Bahar, Samsonova, Anastasia A, Neumüller, Ralph A, Mohr, Stephanie E, Perrimon, Norbert

“…An approach is presented for predicting the nature of the relationship (activating or inhibiting) between interacting proteins via integration of phenotypic…”
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FlyRNAi.org-the database of the Drosophila RNAi screening center and transgenic RNAi project: 2017 update by Hu, Yanhui, Comjean, Aram, Roesel, Charles, Vinayagam, Arunachalam, Flockhart, Ian, Zirin, Jonathan, Perkins, Lizabeth, Perrimon, Norbert, Mohr, Stephanie E

“…The FlyRNAi database of the Drosophila RNAi Screening Center (DRSC) and Transgenic RNAi Project (TRiP) at Harvard Medical School and associated DRSC/TRiP…”
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Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi by Housden, Benjamin E, Valvezan, Alexander J, Kelley, Colleen, Sopko, Richelle, Hu, Yanhui, Roesel, Charles, Lin, Shuailiang, Buckner, Michael, Tao, Rong, Yilmazel, Bahar, Mohr, Stephanie E, Manning, Brendan D, Perrimon, Norbert

“…The tuberous sclerosis complex (TSC) family of tumor suppressors, TSC1 and TSC2, function together in an evolutionarily conserved protein complex that is a…”
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NGS Profiling of Invertebrate Immune Systems by Roesel, Charles

“…Much of what is known about invertebrate immunity has been discovered through genome-wide studies of organisms like Drosophila with well-annotated and curated…”
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Erratum: Integrating protein-protein interaction networks with phenotypes reveals signs of interactions by Vinayagam, Arunachalam, Zirin, Jonathan, Roesel, Charles, Hu, Yanhui, Yilmazel, Bahar, Samsonova, Anastasia A, Neumüller, Ralph A, Mohr, Stephanie E, Perrimon, Norbert

“…Nat. Methods 11, 94–99 (2014); published online 17 November 2013; corrected after print 17 March 2014 In the version of this article initially published, there…”
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Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets by Vinayagam, Arunachalam, Gibson, Travis E, Lee, Ho-Joon, Yilmazel, Bahar, Roesel, Charles, Hu, Yanhui, Kwon, Young, Sharma, Amitabh, Liu, Yang-Yu, Perrimon, Norbert, Barabási, Albert-László

“…The protein-protein interaction (PPI) network is crucial for cellular information processing and decision-making. With suitable inputs, PPI networks drive the…”
Get full text