Search Results - "Roes, CB"

Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: a multicentre, double-blind, placebo-controlled randomised trial by van Eijk, Maarten MJ, MD, Roes, Kit CB, Prof, Honing, Marina LH, MD, Kuiper, Michael A, MD, Karakus, Attila, MD, van der Jagt, Mathieu, MD, Spronk, Peter E, MD, van Gool, Willem A, Prof, van der Mast, Roos C, Prof, Kesecioglu, Jozef, Prof, Slooter, Arjen JC, Dr

“…Summary Background Delirium is frequently diagnosed in critically ill patients and is associated with adverse outcome. Impaired cholinergic neurotransmission…”
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Recommendations for the design of small population clinical trials by Day, Simon, Jonker, Anneliene Hechtelt, Lau, Lilian Pek Lian, Hilgers, Ralf-Dieter, Irony, Ilan, Larsson, Kristina, Roes, Kit Cb, Stallard, Nigel

“…Orphan drug development faces numerous challenges, including low disease prevalence, patient population heterogeneity, and strong presence of paediatric…”
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Sequential designs with small samples: Evaluation and recommendations for normal responses by Nikolakopoulos, Stavros, Roes, Kit CB, van der Tweel, Ingeborg

“…Sequential monitoring is a well-known methodology for the design and analysis of clinical trials. Driven by the lower expected sample size, recent guidelines…”
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Why was this transfusion given? Identifying clinical indications for blood transfusion in health care data by van Hoeven, Loan R, Kreuger, Aukje L, Roes, Kit Cb, Kemper, Peter F, Koffijberg, Hendrik, Kranenburg, Floris J, Rondeel, Jan Mm, Janssen, Mart P

“…To enhance the utility of transfusion data for research, ideally every transfusion should be linked to a primary clinical indication. In electronic patient…”
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Meta-analyses triggered by previous (false-)significant findings: problems and solutions by Schuit, Ewoud, Roes, Kit C B, Mol, Ben W J, Kwee, Anneke, Moons, Karel G M, Groenwold, Rolf H H

“…Meta-analyses are typically triggered by a (potentially false-significant) finding in one of the preceding primary studies. We studied consequences of…”
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Challenges of defining a non-inferiority margin: a case study of non-inferiority randomized controlled trials of oral anti-thrombolytic agents for prophylaxis of venous thromboembolic events after orthopedic surgery by Wangge, Grace, Klungel, Olaf H, Roes, Kit CB, de Boer, Antonius, Hoes, Arno W, Knol, Mirjam J

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Multimodal nocturnal seizure detection in a residential care setting: A long-term prospective trial by Arends, Johan, Thijs, Roland D, Gutter, Thea, Ungureanu, Constantin, Cluitmans, Pierre, Van Dijk, Johannes, van Andel, Judith, Tan, Francis, de Weerd, Al, Vledder, Ben, Hofstra, Wytske, Lazeron, Richard, van Thiel, Ghislaine, Roes, Kit C.B, Leijten, Frans

“…OBJECTIVETo develop and prospectively evaluate a method of epileptic seizure detection combining heart rate and movement. METHODSIn this multicenter, in-home,…”
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Dealing With Missing Outcome Data in Randomized Trials and Observational Studies by Groenwold, Rolf H. H., Donders, A. Rogier T., Roes, Kit C. B., Harrell, Frank E., Moons, Karel G. M.

“…Although missing outcome data are an important problem in randomized trials and observational studies, methods to address this issue can be difficult to apply…”
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Reporting of covariate selection and balance assessment in propensity score analysis is suboptimal: a systematic review by Ali, M. Sanni, Groenwold, Rolf H.H, Belitser, Svetlana V, Pestman, Wiebe R, Hoes, Arno W, Roes, Kit C.B, Boer, Anthonius de, Klungel, Olaf H

“…Abstract Objectives To assess the current practice of propensity score (PS) analysis in the medical literature, particularly the assessment and reporting of…”
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The Power of 1: Systematic Review of N-of-1 Studies in Rare Genetic Neurodevelopmental Disorders by Müller, Annelieke R, Brands, Marion MMG, van de Ven, Peter M, Roes, Kit CB, Cornel, Martina C, van Karnebeek, Clara DM, Wijburg, Frits A, Daams, Joost G, Boot, Erik, van Eeghen, Agnies M

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Methods to control for unmeasured confounding in pharmacoepidemiology: an overview by Uddin, Md. Jamal, Groenwold, Rolf H. H., Ali, Mohammed Sanni, de Boer, Anthonius, Roes, Kit C. B., Chowdhury, Muhammad A. B., Klungel, Olaf H.

“…Background Unmeasured confounding is one of the principal problems in pharmacoepidemiologic studies. Several methods have been proposed to detect or control…”
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Exploring interaction effects in small samples increases rates of false-positive and false-negative findings: results from a systematic review and simulation study by Schmidt, Amand F, Groenwold, Rolf H.H, Knol, Mirjam J, Hoes, Arno W, Nielen, Mirjam, Roes, Kit C.B, de Boer, Anthonius, Klungel, Olaf H

“…Abstract Objective To give a comprehensive comparison of the performance of commonly applied interaction tests. Methods A literature review and simulation…”
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Level of evidence for promising subgroup findings in an overall non-significant trial by Tanniou, Julien, Tweel, Ingeborg van der, Teerenstra, Steven, Roes, Kit CB

“…In drug development and drug licensing, it sometimes occurs that a new drug does not demonstrate effectiveness for the full study population, but there appears…”
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Rapid response to methylphenidate as an add-on therapy to mirtazapine in the treatment of major depressive disorder in terminally ill cancer patients: A four-week, randomized, double-blinded, placebo-controlled study by Ng, Chong Guan, Boks, Marco P.M, Roes, Kit C.B, Zainal, Nor Zuraida, Sulaiman, Ahmad Hatim, Tan, Seng Beng, de Wit, Niek J

“…Abstract This is a 4 week, randomized, double-blind, placebo-controlled study to examine the effects of methylphenidate as add-on therapy to mirtazapine…”
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Selecting a classification function for class prediction with gene expression data by Jong, Victor L, Novianti, Putri W, Roes, Kit C B, Eijkemans, Marinus J C

“…Class predicting with gene expression is widely used to generate diagnostic and/or prognostic models. The literature reveals that classification functions…”
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Justification of exclusion criteria was underreported in a review of cardiovascular trials by Schmidt, Amand F, Groenwold, Rolf H.H, van Delden, Johannes J.M, van der Does, Yuri, Klungel, Olaf H, Roes, Kit C.B, Hoes, Arno W, van der Graaf, Rieke

“…Abstract Objectives Ethical guidelines for human subject research require that the burdens and benefits of participation be equally distributed. This study…”
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Comparing HAMD17 and HAMD subscales on their ability to differentiate active treatment from placebo in randomized controlled trials by Boessen, Ruud, Groenwold, Rolf H.H, Knol, Mirjam J, Grobbee, Diederick E, Roes, Kit C.B

“…Abstract Background The 17-item Hamilton depression rating scale (HAMD17 ) is the standard efficacy outcome in antidepressant clinical trials. It is criticized…”
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The SNAP trial: a double blind multi-center randomized controlled trial of a silicon nitride versus a PEEK cage in transforaminal lumbar interbody fusion in patients with symptomatic degenerative lumbar disc disorders: study protocol by Kersten, Roel F M R, van Gaalen, Steven M, Arts, Mark P, Roes, Kit C B, de Gast, Arthur, Corbin, Terry P, Öner, F Cumhur

“…Polyetheretherketone (PEEK) cages have been widely used in the treatment of lumbar degenerative disc disorders, and show good clinical results. Still,…”
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Estimates of subgroup treatment effects in overall nonsignificant trials: To what extent should we believe in them? by Tanniou, Julien, Tweel, Ingeborg, Teerenstra, Steven, Roes, Kit C.B.

“…In drug development, it sometimes occurs that a new drug does not demonstrate effectiveness for the full study population but appears to be beneficial in a…”
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Effects of recruitment strategies and demographic factors on inclusion in a large scale vaccination trial in adults 65 years and older by Smorenburg, Andre J, Oosterman, Bas J, Grobbee, Diederick E, Bonten, Marc J.M, Roes, Kit C.B

“…Highlights • We determined associations between patient and study-related factors and inclusion. • Inclusion was associated with travel time and the number of…”
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