Search Results - "Roen, Diana R"

Comprehensive Evaluation of the Expressed CD8+ T Cell Epitope Space Using High-Throughput Epitope Mapping by Lehmann, Paul V, Suwansaard, Maneewan, Zhang, Ting, Roen, Diana R, Kirchenbaum, Greg A, Karulin, Alexey Y, Lehmann, Alexander, Reche, Pedro A

“…T cell immunity is traditionally assessed through functional recall assays, which detect the consequences of the T cells' antigen encounter, or via…”
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High-Throughput GLP-Capable Target Cell Visualization Assay for Measuring Cell-Mediated Cytotoxicity by Welter, Anna, Sundararaman, Srividya, Li, Ruliang, Zhang, Ting, Karulin, Alexey Y, Lehmann, Alexander, Naeem, Villian, Roen, Diana R, Kuerten, Stefanie, Lehmann, Paul V

“…One of the primary effector functions of immune cells is the killing of virus-infected or malignant cells in the body. Natural killer (NK) and CD8 effector T…”
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An Enhanced ELISPOT Assay for Sensitive Detection of Antigen-Specific T Cell Responses to Borrelia burgdorferi by Jin, Chenggang, Roen, Diana R, Lehmann, Paul V, Kellermann, Gottfried H

“…Lyme Borreliosis is an infectious disease caused by the spirochete Borrelia burgdorferi that is transmitted through the bite of infected ticks. Both B…”
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Unbiased, High-Throughput Identification of T Cell Epitopes by ELISPOT by Lehmann, Paul V, Roen, Diana R, Lehmann, Alexander A

“…Recent systematic immune monitoring efforts suggest that, in humans, epitope recognition by T cells is far more complex than has been assumed based on…”
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Natural T cell autoreactivity to melanoma antigens: clonally expanded melanoma-antigen specific CD8 + memory T cells can be detected in healthy humans by Przybyla, Anna, Zhang, Ting, Li, Ruliang, Roen, Diana R., Mackiewicz, Andrzej, Lehmann, Paul V.

“…We used four-color ImmunoSpot® assays, in conjunction with peptide pools that cover the sequence of tyrosinase (Tyr), melanoma-associated antigen A3 (MAGE-A3),…”
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Four Color ImmunoSpot ® Assays for Identification of Effector T-Cell Lineages by Hanson, Jodi, Roen, Diana R, Lehmann, Paul V

“…Single color IFN-γ ELISPOT assays have evolved as a highly sensitive T cell immune monitoring platform. By detecting individual T cells that secrete IFN-γ in…”
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Multiplex ImmunoSpot ® Assays for the Study of Functional B Cell Subpopulations by Roen, Diana R, Hanson, Jodi, Lehmann, Paul V

“…B cells mediate humoral immunity by producing antibody molecules, but they also participate in innate and acquired immune functions via the secretion of…”
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