Search Results - "Roemer, Sarah C."
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The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones
Published in eLife (30-09-2016)“…The histone chaperone Chromatin Assembly Factor 1 (CAF-1) deposits tetrameric (H3/H4) histones onto newly-synthesized DNA during DNA replication. To understand…”
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Structural and functional analysis of domains of the progesterone receptor
Published in Molecular and cellular endocrinology (30-01-2012)“…► This paper reviews the structural dynamics of steroid hormone receptors. ► The hinge region and amino-terminal domain (NTD) are intrinsically disordered…”
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A Progesterone Receptor Co-activator (JDP2) Mediates Activity through Interaction with Residues in the Carboxyl-terminal Extension of the DNA Binding Domain
Published in The Journal of biological chemistry (04-09-2009)“…Progesterone receptor (PR) belongs to the nuclear receptor family of ligand-dependent transcription factors and mediates the major biological effects of…”
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Mechanism of high-mobility group protein B enhancement of progesterone receptor sequence-specific DNA binding
Published in Nucleic acids research (01-06-2008)“…The DNA-binding domain (DBD) of progesterone receptor (PR) is bipartite containing a zinc module core that interacts with progesterone response elements (PRE),…”
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CAF-1-induced oligomerization of histones H3/H4 and mutually exclusive interactions with Asf1 guide H3/H4 transitions among histone chaperones and DNA
Published in Nucleic acids research (01-12-2012)“…Anti-silencing function 1 (Asf1) and Chromatin Assembly Factor 1 (CAF-1) chaperone histones H3/H4 during the assembly of nucleosomes on newly replicated DNA…”
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The C-terminal Extension (CTE) of the Nuclear Hormone Receptor DNA Binding Domain Determines Interactions and Functional Response to the HMGB-1/-2 Co-regulatory Proteins
Published in The Journal of biological chemistry (12-07-2002)“…Previously, we and others reported that the high mobility group proteins, HMGB-1/-2, enhance DNA binding in vitro and transactivation in situ by the steroid…”
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Reversed-phase ion-pair liquid chromatography method for purification of duplex DNA with single base pair resolution
Published in Nucleic acids research (01-11-2013)“…Obtaining quantities of highly pure duplex DNA is a bottleneck in the biophysical analysis of protein-DNA complexes. In traditional DNA purification methods,…”
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Structure of the Progesterone Receptor-Deoxyribonucleic Acid Complex: Novel Interactions Required for Binding to Half-Site Response Elements
Published in Molecular endocrinology (Baltimore, Md.) (01-12-2006)“…The DNA binding domain (DBD) of nuclear hormone receptors contains a highly conserved globular domain and a less conserved carboxyl-terminal extension (CTE)…”
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Thermodynamic insights into histone transfer among chaperones
Published in Epigenetics & chromatin (08-04-2013)“…Doc number: P111…”
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